Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.
However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.
New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.
The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.
It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.
"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.
As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.
"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.
"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.
To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.
At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.
Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.
In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.
They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.
Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.
The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.
Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.
Comments
Hinduism is the religion of foolish people.
They worship Cow, Rat, Monkey, Pig etc.........
Drinks Cow urine as theertha, and throws milk on stones
But doesnt know how to treat humans.
Hinduism is in the declining stage, so they are trying to protect hinduism by attacking on others for no reasons. Because they are scared people.
Dear proud Hindu, if you have guts, please go to Kerala/ Bengal / Tamil Nadu and stop Hindus from eating beef. Hindus are eating beef in these states more than muslims do. If gow matha is so sacred for Hindus, why dont you go to Nepal and stop slaughtering hundreds of cows in the temple festival there. Why are you so jealous.
No need to explain anything just see below & comment.
Largest beef suppliers of India.............
1. Mr. Shatish - Mumbai
2. Mr. Sunil - Mumbai
3. Mr. Madan - Delhi
4. Mr. Bindra - Chandigarh
would see a developed India if these goons has guts to do it to a murderer or rapist who are free outside...........
By the way last noon at sullia i saw a bull mating a cow....any solution to give GO Maa a Bedroom than going to streets....
Suhag Raat for cows first. Sauchaalay comes next
Mr suresh one day ur mom or sister will suffer same humiliation then u will under stand ..shameless creature
If you have the guts go and stop slaughtering and exporting cattle to many foreign countries. Double standard idiots.
Do they respect their own real mata sitting at home....forget it do they put a little grass for cows which loiter around city streets...all these things happening around are bullshits... and election gimmick....UP Election...coming.....expect more and more dalits and women will be beaten everywhere....please be careful...
Muslims please do not eat beef at least until UP election.....after which hindutva group themselves will sell cows for muslims....
Proud Hindu............be proud on Good things......you are following what evil is taught to you
Mohan pajir
You must be sleeping these days or pretending to be slept. Do you know gowmatha slaughtering by your brothers in Goa and north east states. Do you who stands first in the world in beef exxport. Its your brothers and children of gowmatha.
i love eating beef !!!!! u guys really need to taste them its awesome...slrruuuuuppppppppp .... then u ll forget about this maatha pitha and all :)
the word is \napunsak\""
looks like guys like proud hindu, mohan & srikanth .doesnt mind when our hindu sisters getting raped and murdered and yet they dont want justice for them
rather they want to beat women in the name of holy meat
@ Mohan Pajir
U need to do surveillance in night time bec ur gomatha, ur mother sleeping in road and without food sometimes ...
take care about that first then u look for ur own mother
Screaming 'Gav Mathaa ki jai' 'Bharat Maatha ki jai' by beating a real alive maatha (women).
ISIS campaigning in US by killing and attacking people there and here Sangh campaigning for BJP by these activities.
Cowards.
mr mohan, pajir
first go and save your matha.[feed her.] shame on you man
Proud Hindu, Mohan Pajir, Suresh Mahajan........Why are you hiding in RAT HOLES when your Go mathas are killed in Gujrat for export..... India is the highest beef supplier to gulf countries..... They are all eating and enjoying your Go Matha provided by Gujrat..... Go and show your Mardangi in Gujrat ....
SAFFRON TERRORISTS, NOT ACTIVISTS,
its not a gau maatha its their pitha...(Buffalo not a cow)
Nothing to say about the Hijda Police..... Naren / Bopanna ,,,do have any comments..... This buffalo meat will become Cow meat in another 6 months..... Chamatkar of Modi Sarkar......shame..
India tu kya se kya hogaya!!!
Society should be ruthless towards those who mercilessly kill cows and eat its meet. Funny thing is that they can kill Gau maatha and eat its meet but we are not even supposed to touch their maatha!!!??? What kind of rules is this???
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