Nepal's death toll soars to 3,815

April 27, 2015

Kathmandu, Apr 27: The death toll from the 7.9 magnitude temblor that struck Nepal was on Monday placed at 3,815, with Kathmandu accounting for nearly 1,000 deaths.

The home ministry said in a statement another 6,515 people had been injured. The Saturday earthquake, the worst to hit Nepal after 1934, had its epicentre in Gorkha district.

The highest death toll of 1,021 among all districts was reported from Sindhupalchowk, about 65 km from here. Kathmandu, where damage to property was maximum, saw 920 fatalities.

Nuwakot district accounted for 422 deaths, Dhading 299, Bhaktapur 240, Gorkha 223, Kavre 193, Lalitpur 157 and Rasuwa district 150.

The other fatalities were reported from Dolakha (46), Makawanpur (33), Ramechap (26), Solu (21), Okhaldunga (16), Sindhuli (9), Sunsari (7), Chitwan and Bara (5 each), Lamjung (4), Parsa (3), Kaski, Bhojpur and Mornag (2 each) and Saptari, Dhanusha, Taplegunj, Sarhahi, Rauthat,

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Earlier

Nepal earthquake toll rises above 3,600

Kathmandu, Apr 27: Rescue workers today intensified efforts to locate survivors trapped under tonnes of rubble of flattened homes and buildings in earthquake-hit Nepal amid concerns that death toll could rise from more than 3,600 with rescue teams reaching remote mountainous areas.

Racing against time, multi-national rescue teams with sniffer dogs and advanced equipment are desperately trying to locate survivors as hundreds of people are still missing.

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More than 700 disaster relief experts drawn from the National Disaster Relief Force have been deployed by India.

In a statement, Nepalese police today said the death toll had risen to 3,617 people. That does not include the 22 people killed in the avalanche on Mount Everest.

Nepalese Home ministry's national disaster management division said more than 6,830 people were injured.

1,053 people are reported killed in the Kathmandu Valley alone and 875 in Sindhupalchowk, it said.

Officials and aid agencies have warned that the casualties could rise as rescue teams reach remote mountainous areas of western Nepal.

"Villages are routinely affected by landslides, and it's not uncommon for entire villages of 200, 300, up to 1,000 people to be completely buried by rock falls," aid agency World Vision spokesman Matt Darvas said.

The blocked roads, downed power lines and overcrowded hospitals along with fresh tremors are hampering rescue efforts to locate survivors of the Saturday's 7.8 magnitude quake that had its impact in several cities in Bihar, West Bengal and UP northeast India.

It was also felt in Southern and Western parts of India, China, Bhutan and as far as Pakistan and Bangladesh.

Officials said five Indians, including the daughter of an Indian embassy employee, were among those killed in the quake.

Tens of thousands of people were forced to spend the two consecutive nights sleeping in open in makeshift plastic tents barely shielding them from the pouring rain.

Earlier:

Nepal quake: Death toll crosses 3,200; sick and wounded lay out in the open

Kathmandu, Apr 27: Thousands of desperate Nepalese huddled under tents and sought scarce food and medical supplies on Monday, two days after a massive quake killed more than 3,200 people and overwhelmed authorities struggled to cope with the disaster.

The sick and wounded lay out in the open in the capital, Kathmandu, unable to find beds in the devastated city's hospitals. Surgeons set up an operating theater inside a tent in the grounds of Kathmandu Medical College.

"We are overwhelmed with rescue and assistance requests from all across the country," said Deepak Panda, a member of the country's disaster management.

Across Kathmandu and beyond, exhausted families whose homes were either flattened or at risk of collapse laid mattresses out on streets and erected tents to shelter from rain.

People queued for water dispensed from the back of trucks, while the few stores still open had next to nothing on their shelves. Crowds jostled for medicine at one pharmacy.

High in the Himalayas, hundreds of foreign and Nepalese climbers remained trapped after a huge avalanche ripped through the Mount Everest base camp, killing 17 people in the single worst disaster to hit the world's highest mountain.

A total of 3,218 people were confirmed killed in the 7.9 magnitude quake, a police official said on Monday, the worst in Nepal since 1934 when 8,500 died. More than 6,500 were injured.

Another 66 were killed across the border in India and at least another 20 in Tibet, China's state news agency said.

The toll is likely to climb as rescuers struggle to reach remote regions in the impoverished, mountainous country of 28 million people and as bodies buried under rubble are recovered.

"The rescue workers are in a really bad shape. We are all about to collapse. We have worked two straight nights," said home ministry official Laxmi Prasad Dhakal.

With so many people sleeping in the open with no power or water and downpours forecast, fears mounted of major food and water shortages. Across Nepal, hundreds of villages have been left to fend for themselves.

"There is no electricity, no water. Our main challenge and priority is to restore electricity and water," Dhakal said.

"The next big challenge is the supply of food. Shopkeepers are unable to go in and open their shops. So people are facing difficulty buying food."Several countries rushed to send aid and personnel.

India flew in medical supplies and members of its National Disaster Response Force. China sent a 60-strong emergency team. Pakistan's army said it was sending four C-130 aircraft with a 30-bed hospital, search and rescue teams and relief supplies.

A Pentagon spokesman said a U.S. military aircraft with 70 personnel left the United States on Sunday and was due in Kathmandu on Monday. Australia, Britain and New Zealand said they were sending specialist urban search-and-rescue teams to Kathmandu at Nepal's request.

Britain, which believes several hundred of its nationals are in Nepal, was also delivering supplies and medics.

However, there has been little sign of international assistance on the ground so far, with some aid flights prevented from landing by aftershocks that closed Kathmandu's main airport several times on Sunday.

AVALANCHE TERROR

In the Himalayas, hundreds of climbers felt tremors on Sunday powerful enough to send snow and boulders cascading towards them. Another was felt early on Monday.

The huge and deadly avalanche on Saturday triggered by the earthquake caused panic at the Everest base camp, a sprawling "city" of tents from where mountaineers set off for the world's highest peak.

"It was a monstrous sound, like the demons had descended on the mountain," Khile Sherpa, a Nepalese guide, told Reuters, recalling the moment the avalanche hit.

He was one of the lucky few airlifted to the relative safety of Kathmandu but the disaster has underlined the woeful state of Nepal's medical facilities.

Nepal has only 2.1 physicians and 50 hospital beds for every 10,000 people, according to a 2011 World Health Organization report.

"The earthquake has exposed that Nepal's best public hospital infrastructure has crumbled at a time when it should serve more people in a hurry," said Sarvendra Moongla, a senior surgeon at Bir Hospital's Trauma Center in Kathmandu, which opened in February.

At the Tribhuvan University Teaching Hospital, bodies, including that of a boy aged about seven, were heaped in a dark room. The stench of death was overpowering.

Rajiv Biswas, Asia Pacific chief economist at business research firm IHS, said long-term reconstruction costs in Nepal using proper building standards for an earthquake zone could be more than $5 billion, or around 20 percent of the country's GDP.

"With housing construction standards in Nepal being extremely low ... the impact of the earthquake has been devastating based on initial reports," he said in an early analysis of the likely damage.

In crowded Kathmandu, many buildings were flattened or badly damaged.

Among the capital's landmarks destroyed in the earthquake was the 60-metre (200-foot) Dharahara Tower, built in 1832 for the queen of Nepal.

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Earlier post:

Death toll crosses 2,000 in Nepal quake as fresh jolts felt

Kathmandu, Apr 26: Rescuers today dug with bare hands and heavy equipment through tonnes of rubble for survivors as toll from the devastating temblor crossed the 2,000-mark in Nepal's worst quake in over 80 years, with fresh aftershocks triggering panic and hampering relief efforts.

A strong 6.7-magnitude aftershock sent people running for open spaces as they struggled with the devastation caused by yesterday's massive 7.9-magnitude temblor that displaced and injured thousands besides causing a deadly avalanche on the Mount Everest claiming 17 lives.

"The latest figure says more than 2,000 people have died and several thousands have been wounded and more counts are coming," said Narayan Khatkar, Nepal's Urban Development Minister.

A police official told media here that 2,123 people were killed.Over 5,000 people were also injured in the earthquake and the dozen aftershocks that continued till today, with the strongest measuring 6.7 on the Richter Scale.Climbers on Mount Everest said they saw fresh series of avalanches and a big landslide in the base camp.

International teams, including from India, have touched down quake-hit Nepal that has declared a state of emergency in the wake of the disaster caused, the worst in over 80 years of Nepal's recorded history.

Rescuers have been hunting for survivors under heaps of debris with bare hands as well as heavy equipment though the efforts have been hampered due to fresh tremors and thunderstorms.

Locals and tourists sifted through mounds of debris for survivors. Cheers rose when people were found alive, thought mostly bodies were pulled out.

The earthquake and the aftershocks left behind a trail of death and destruction, flattening houses and buildings, including the iconic Dharhara tower and the landmark Darbar Square in the heart of the capital, trapping scores of people.

Thousands of people spent last night in the open in chilly weather, anticipating more aftershocks.

1,053 people are reported killed in the Kathmandu Valley alone. Officials fear the death toll could rise as desperate search for survivors continued.

According to initial reports related to today's aftershock, a tunnel caved in at the Trishuli Hydel Project and around 60 labourers are feared trapped.

MI-17 helicopters of the Indian Air Force (IAF) have carried out five casualty evacuation sorties and the injured have been moved to military hospitals.

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As many as 17 Mount Everest climbers, including foreigners, were reportedly killed in an avalanche triggered by the earthquake.

The latest aftershock hit at a shallow depth of 10 kilometres at 12:39 IST, according to the US Geological Survey.

The aftershock was registered 17 kilometres south of Kodari - 114 kilometres north of here - near the Tibet Autonomous Region of China.

The tremors - that were felt also in India including its national capital - sent people running for open spaces.

According to reports, the route to the base camp has been destroyed and the IAF choppers were trying to rescue the survivors, around 100 in number including foreigners who were said to be safe.

A climber Jim Davidson said he felt the aftershock at Camp One on Mount Everest.

"Just had our biggest aftershock yet here at C1 on Everest. Smaller than original quake but glacier shook & avalanches," he tweeted.

An Indian attempting to climb all the highest peaks in the seven continents, 54-year-old Ankur Bahl is also stuck at Camp II on Mount Everest along with 11 other fellow climbers.

Bahl had moved to Camp II from Camp I yesterday but is now stranded due to the earthquake, his friends in New Delhi said.

Two Indians, including the daughter of an Indian embassy employee, were among those killed in the powerful earthquake, an Indian embassy official said.

A house in the Indian Embassy complex collapsed, killing the daughter of a CPWD employee. Death of another Indian was reported at Bir Hospital here.

Over 550 Indians have been evacuated by the IAF from earthquake-hit Nepal even as India stepped up its relief and rescue mission with 10 flights and 12 helicopters scheduled to carry specialists and equipment to Kathmandu today.

The Tribhuvan International Airport, that was closed down yesterday following the quake, was opened briefly, only to be shut down again due to fresh tremors.

IndiGo, SpiceJet flights could not land here and were forced to return as Air Traffic Control personnel at the airport were evacuated following fresh aftershocks.

Many hospitals in Nepal are struggling to cope with the large number of injured.

Nepal Prime Minister Sushil Koirala, who was on a visit to Indonesia, had to cut short his trip in the wake of the disaster.

The Nepalese government has declared a national crisis and established a fund of Rs 500 million for the reconstruction of the damaged infrastructure.

Many areas in the country have no electricity for the past 24 hours and authorities say the situation is likely to continue for the next few days.

Offers of help poured in from around the world, with the US, the European Union as well the United States saying they were sending in disaster response teams.

"The United Nations is supporting the Government of Nepal in coordinating international search and rescue operations and is preparing to mount a major relief effort," UN Secretary- General Ban said in a statement today.

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Agencies
March 28,2020

Canadian researchers are developing a DNA vaccine for SARS-CoV-2, the coronavirus that causes COVID-19 and has currently infected nearly 5,00,000 people worldwide and crippled the global economy.

Entos Pharmaceuticals, a health-care biotechnology company headed by a University of Alberta researchers, develop new therapeutic compounds using the company's proprietary drug-delivery platform and has begun manufacturing vaccine candidates against the novel coronavirus.

"Given the urgency of the situation, we can have a lead candidate vaccine within two months. Once we have that it's a race to get it into clinical trials," said John Lewis, CEO of Entos and a Professor at the University of Alberta in Canada.

Lewis said in comparison to a traditional vaccine, DNA-based vaccines hold several advantages.

Nucleic acids are introduced directly into the patient's own cells, causing them to make pieces of the virus--tricking the immune system into mounting a response without the full virus actually being present, the researcher said.

According to the company, the approach is recognised as being easier to move into large-scale manufacturing, offers improved vaccine stability and works without needing an infectious agent.

In the current absence of a vaccine for COVID-19, several companies around the world are mounting efforts to begin similar work.

The first clinical trial using a DNA-based vaccine developed by Moderna Inc.in the US on March 13.

Their approach allows for antibodies to be made in the human trial volunteers against a specific protein on the surface of the coronavirus that lets the virus enter human cells.

The hope is that the antibodies will stop the interaction.

Though this approach is designed to be effective against COVID-19 specifically, Lewis said Entos is taking a different tack.

The company plans to use plasmid DNA to amplify the production of key coronavirus surface and structural proteins with each injection, with an eye to the bigger picture.

"Many of the structural proteins in the virus are pretty well conserved across all the coronaviruses, including SARS and MERS," said Lewis.

"We're hoping that if we express more of the structural proteins that are common to most coronaviruses, we can inhibit the current COVID-19, and also potentially protect against all coronaviruses both past and future," Lewis added.

To move the project forward quickly, the company is seeking financial support from both provincial and federal levels of government.

"We have the opportunity to save a lot of lives, and I think it's really upon us and governments to find solutions for that," Lewis said.

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News Network
May 19,2020

May 19: A Chinese laboratory has been developing a drug it believes has the power to bring the coronavirus pandemic to a halt.

The outbreak first emerged in China late last year before spreading across the world, prompting an international race to find treatments and vaccines.

A drug being tested by scientists at China's prestigious Peking University could not only shorten the recovery time for those infected, but even offer short-term immunity from the virus, researchers say.

Sunney Xie, director of the university's Beijing Advanced Innovation Center for Genomics, told AFP that the drug has been successful at the animal testing stage.

"When we injected neutralising antibodies into infected mice, after five days the viral load was reduced by a factor of 2,500," said Xie.

"That means this potential drug has (a) therapeutic effect."

The drug uses neutralising antibodies -- produced by the human immune system to prevent the virus infecting cells -- which Xie's team isolated from the blood of 60 recovered patients.

A study on the team's research, published Sunday in the scientific journal Cell, suggests that using the antibodies provides a potential "cure" for the disease and shortens recovery time.

Xie said his team had been working "day and night" searching for the antibody.

"Our expertise is single-cell genomics rather than immunology or virology. When we realised that the single-cell genomic approach can effectively find the neutralising antibody we were thrilled."

He added that the drug should be ready for use later this year and in time for any potential winter outbreak of the virus, which has infected 4.8 million people around the world and killed more than 315,000.

"Planning for the clinical trial is underway," said Xie, adding it will be carried out in Australia and other countries since cases have dwindled in China, offering fewer human guinea pigs for testing.

"The hope is these neutralised antibodies can become a specialised drug that would stop the pandemic," he said.

China already has five potential coronavirus vaccines at the human trial stage, a health official said last week.

But the World Health Organization has warned that developing a vaccine could take 12 to 18 months.

Scientists have also pointed to the potential benefits of plasma -- a blood fluid -- from recovered individuals who have developed antibodies to the virus enabling the body's defences to attack it.

More than 700 patients have received plasma therapy in China, a process which authorities said showed "very good therapeutic effects".

"However, it (plasma) is limited in supply," Xie said, noting that the 14 neutralising antibodies used in their drug could be put into mass production quickly.

Using antibodies in drug treatments is not a new approach, and it has been successful in treating several other viruses such as HIV, Ebola and Middle East Respiratory Syndrome (MERS).

Xie said his researchers had "an early start" since the outbreak started in China before spreading to other countries.

Ebola drug Remdesivir was considered a hopeful early treatment for COVID-19 -- clinical trials in the US showed it shortened the recovery time in some patients by a third -- but the difference in mortality rate was not significant.

The new drug could even offer short-term protection against the virus.

The study showed that if the neutralising antibody was injected before the mice were infected with the virus, the mice stayed free of infection and no virus was detected.

This may offer temporary protection for medical workers for a few weeks, which Xie said they are hoping to "extend to a few months".

More than 100 vaccines for COVID-19 are in the works globally, but as the process of vaccine development is more demanding, Xie is hoping that the new drug could be a faster and more efficient way to stop the global march of the coronavirus.

"We would be able to stop the pandemic with an effective drug, even without a vaccine," he said.

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News Network
March 25,2020

London, Mar 25: Prince Charles on Wednesday has tested positive for the novel coronavirus and is working from home with mild symptoms, according to UK media.
A Clarence House spokesperson said the Prince of Wales was "displaying mild symptoms but otherwise remains in good health and has been working from home throughout the last few days as usual", the Telegraph UK reported.
"He has been displaying mild symptoms but otherwise remains in good health and has been working from home throughout the last few days as usual," the spokesperson added.
In accordance with the government and medical advice, the 71-year old heir to the British throne and Camilla, the Duchess of Cornwall, are now self-isolating at their home in Scotland.
The Duchess of Cornwall has also been tested but does not have the virus.
The tests were carried out by the NHS in Aberdeenshire where they met the criteria required for testing.
"It is not possible to ascertain from whom the Prince caught the virus owing to the high number of engagements he carried out in his public role during recent weeks," the statement further said.

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