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May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.

According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.

"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.

They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.

Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.

"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.

"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.

In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.

"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.

The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.

These children were then confirmed to have COVID-19.

While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.

Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.

According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.

"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.

Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.

While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.

However, he cautioned that more research is needed to confirm their findings.

"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.

Bengaluru, Jan 6: A delegation of Christians, led by Peter Machado, archbishop of Bengaluru, met chief minister BS Yediyurappa on Sunday and sought an amicable solution to the issue of installing a statue of Jesus Christ atop Kapalibetta in Harobele village, Kanakapura taluk.

Yediyurappa is learnt to have assured the delegation of doing the needful and said he would take a decision after the revenue department submits its report. The department is looking into various aspects of the issue, including the sanction of 10 acres of land for the purpose.

“The meeting was cordial and the chief minister lent us a patient hearing. Our only request was to settle the issue in a way that is acceptable to all sections of society,” Machado said. Congress functionary and Kanakapura legislator DK Shivakumar had laid the foundation stone for the 114-foot statue of Christ on Kapalibetta on Christmas Day at an event organised by the Harobele Kapalibetta Development Trust, which plans to install the statue.

The issue took a political hue when BJP functionaries objected, saying the land sanctioned to the trust is part of gomala (reserved for cattle grazing) land and any religious activity there would be illegal. Revenue minister R Ashoka sought a report and department officials said they would submit it in a week’s time.

Bengaluru, Mar 6: The Karnataka government has directed school authorities to grant leave to students and staff suffering from cold or fever in the light of renewed coronavirus (COVID -19) fears.

"If any student, teacher of staff is suffering from respiratory infections, they should be granted leave. They should be allowed to come back to school only after confirming from the doctor that they are cured. In case of a student or staff staying at hostels developing any symptoms, they should be kept in a separate room," said the government circular.

Aiming at containing the spread of coronavirus, Sriramulu said, "We have formed 1,680 isolation wards in private hospitals. Chief Minister B.S. Yediyurappa has apprised Prime Minister Narendra Modi and Union Health Minister of the situation."

However, the Health Minister said no positive case has been recorded till now in the state.

"Tests are also being conducting on passengers arriving in Karnataka and all precautionary measures are being taken," said Sriramulu about the 40,000 people thermal screened at the Kempegowda International Airport (KIA) in the city. Major private hospitals in the city have geared up to treat suspected cases.

Five Karnataka districts bordering Kerala -- Dakshina Kannada, Kodagu, Udupi, Chamarajanagar and Mysuru -- continue to be under surveillance after three positive coronavirus cases were reported in Kerala

The deadly virus has killed a total of 2,912 people in mainland China till Saturday, bringing the global death toll to more than 3,000, authorities said on Monday.

The Karnataka Health and Family Welfare Department is observing 461 people under home quarantine even as no positive coronavirus case has been reported from the state, an official said on Thursday.

"We are observing 461 people for Coronavirus symptoms at their residences, however, no positive case has emerged from Karnataka," said state Health Department's Joint Director, Communicable Diseases, Prakash Kumar.

The five people under isolated observation at Rajiv Gandhi Institute of Chest Diseases continue to be so on Thursday as well. As many as 273 samples sent from the state for coronavirus testing reported negative.

In Karnataka, 68,717 passengers have been thermal-screened for the virus until now at Kempegowda International Airport in the city and Mangluru International Airport.

Another 5,103 passengers were also checked for the virus at Karwar and Mangluru seaports.

On Thursday, 16 people completed the mandatory 28-day observation period while a total of 225 people also underwent the same.

Karnataka is screening all international passengers and the state health department met the private sector hospitals to take stock of recent developments.