Quadruplet babies born to Kasargod couple, one dies after month long battle

April 3, 2012

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Mangalore, April 3: A very rare case of four babies of same sex in a single birth (quadruplets) succeeded nearly a month of life by the team effort of highly qualified doctors and medical personals led by Dr Ali kumble in tertiary centre, lndiana Hospital, Mangalore.

However, one among the four babies died on Monday, April 2.

Dr Yusuf kumble Managing Director of the Hospital told media persons that with this Indiana Hospital and Heart Institute's medical team achieved a new milestone in Indian pediatric healthcare.

Aysha Tahira and Latheef hailing from kasargod were not blessed with offspring's for many years. After a prolonged period of waiting they were quite happy to come to know that Aysha has conceived. But the happiness did not last for long time as she delivered prematurely four babies in a single birth. Gynecologist Dr Veena Manjunath was surprised to see new babies one after the other.

The parents were informed that the chance of survival of these babies were extremely rare. Quadruplet incidences occur once in 70 lakh births. These babies survival for more than one week is extremely rare especially if they are very premature. Also it is very expensive and life saving support is required in a high tech care center to make them survive.

Dr Yousuf Kumble said that the four babies got admitted at Indiana hospital's NICU on March 11, this year. Team of doctors led by Dr Ali Kumble took it as a challenge and with their effort babies survived since their admission. Financial support was offered by the hospital management as the father was not in a position to support all the four babies.

“What makes our case still more fascinating is that babies being treated here are identical quadruplet which occurs once in every 13 million births. There are only 60 such cases on record worldwide and it is extremely challenging to ensure they survive into infancy especially if they are born premature at 26 weeks of pregnancy and weigh between 500 to 900 grams”, he said.

He said multiple pregnancies are high risk pregnancies and are associated with increased neonatal morbidity and mortality. The frequency of multiple pregnancies has increased in the past 2 decades, mostly as a result of assisted reproductive techniques for infertile couples.

The average period of gestation in quadruplet pregnancy is 31.2 weeks and the average weight is 1.362 kg as per the literature available. In this case the period of gestation was only 26 weeks and the weights being 900 grams for the first two and 580 grams for the other two offspring, the average weight being only 740 grams, perhaps the first such case of preterm identical quadruplets that goes on record in India, he said.

Dr Kumble said the babies pose serious challenges to both the pediatricians and the family, right from ensuring their survival to the many complications they may develop during their course of hospital stay. “We need to ensure they maintain a normal breathing pattern and tolerate the feed given ok them. Strict hygiene and sanitation to avoid sepsis is a benchmark for ensuring survival of such extremely low birth weight babies. That is why handling and care is undertaken by skilled and experienced nurses assigned specifically for this role”, he said.

“We have taken utmost caution in providing only the mother's milk to the newborns. They have now entered the fourth week of life when chances of intolerance to feeds are high. Survival of such babies beyond the first four weeks of life greatly improves the clinical outcome”, he said.

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Kusuma Kumari G
 - 
Monday, 14 Mar 2016

A VERY GOOD NEWS FOR PARENTS BECAUSE GOD HAS BLESSED THEM WITH FOUR WONDEFUL KIDS.

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News Network
May 12,2020

May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.

According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.

"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.

They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.

Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.

"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.

"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.

In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.

"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.

The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.

These children were then confirmed to have COVID-19.

While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.

Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.

According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.

"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.

Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.

While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.

However, he cautioned that more research is needed to confirm their findings.

"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.

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August 4,2020

Bengaluru, Aug 4: Karnataka on Tuesday reported its biggest single-day spike of 6,259 Covid-19 cases and 110 fresh deaths, taking the total infection count to 1,45,830 and the toll to 2,704, the health department said.

The day also saw a record 6,777 patients getting discharged after recovery, outnumbering the fresh cases. Out of 6,259 fresh cases, a total of 2,035 cases were from Bengaluru Urban district. The previous biggest single-day record was on July 30 when the state added 6,128 cases.

A bulletin from the department said cumulatively 1,45,830 Covid-19 positive cases have been confirmed in the state and it included 2,704 deaths and 69,272 discharges. Out of the 73,846 active cases, as many as 73,212 patients were stable in isolation at designated hospitals while 634 in the intensive care units.

Among the fresh deaths, Bengaluru Urban accounted for 30 followed by Dakshina Kannada (13) and Mysuru (9).

Most of the people who succumbed either had a history of Severe Acute Respiratory Infection (SARI) or Influenza-like illness (ILI), the bulletin said. Besides Bengaluru Urban, the other districts which reported higher fresh cases on Tuesday are Mysuru 662, Kalaburagi 285, Ballari 284, Belagavi 263, Dakshina Kannada 225, Davangere 191, Dharwad and Hassan 188. Bengaluru Urban district continued to top the list of positive cases with a total of 63,033 infections, followed by Ballari 7,638 and Dakshina Kannada 6,388.

Among discharges too Bengaluru Urban tops the districts with 27,877 discharges, followed by Ballari 3,724 and Kalaburagi 3,470. A total of 14,89,016 samples had been tested so far, out of which 42,458 on Tuesday with 29,488 being rapid antigen tests.

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News Network
April 28,2020

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