The tragedy occurred when the driver of the bus plying from Mangalore to Udupi tried to avoid hitting an oncoming car after overtaking another vehicle.
The accident led to road block for a few minutes on National Highway 66.
The ill-fated bus bearing registration number KA 19, C 8811 belonged to 'Maroli Travels'.
The injured, who have been admitted to different hospitals in Udupi and Manipal identified as Shameem Ahmed, Prajna, Suguna, Mohandas, Jagadish, Kiran, Sukanya, Lavita Kotian, Vishwanatha, Uma Subramanya, Rajesh, Ramachandra Prabhu, Sheshagiri, Jagadish Ballal and Kalavathi Bangera.
The condition of three of the injured passenger is said to be critical.
A case has been registered at jurisdictional Kaup police station.
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