No Hajj flights from Mangaluru Airport from 2018?

Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.

However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.

New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.

The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.

It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.

"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.

As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.

"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.

"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.

To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.

At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.

Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.

In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.

They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.

Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.

The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.

Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.

Tirupati, Feb 12: A middle-aged man committed suicide out of fear that he was infected with the dreaded Coronavirus (COVID-19), which has killed over 1000 in China. The deceased identified as Balakrishna (50) was suffering from hypertension. He killed self, after being discharged from hospital, fearing it would spread to his family.  The incident happened in Chittoor district on Monday but came to light only on Tuesday.

Balakrishna was treated in Tirupati last week and told that he had an infection. After two days in the hospital, he got better and returned to his village in Chittoor district on Sunday. But fearing that he was infected with COVID-19, Balakrishna isolated himself from his family. Before committing suicide, he surfed many videos about Coronavirus and also behaved weirdly with the family members by warning them against coming close to him.

“He remained aloof, saying he was infected with coronavirus and asked his family not to come near him. When they tried to approach him, he got agitated, threw stones at them and then locked himself in a room," district medical and health officer Dr M Penchalaiah said.

He was found hanging from a tree near his mother’s grave on the village outskirts. The tragic incident took place in Seshama Naidu Kandriga in Thottambedu block.

According to reports, he was suffering from cold and fever. He went to Tirupati hospital where doctors gave him medicines for viral infection and advised him to wear mask.  He wrongly thought he had coronavirus. However, doctors told Balakrishna he did not have coronavirus.

His son Balamurali said that his father panicked and started saying he needed to kill himself to keep other safe from him and coronavirus. “He began to pelt stones and things at us to keep us away from him,” Balamurali said.

“My father was all worried that the virus would spread to us. He hanged himself to save us,” Murali said.

Thottambedu police sub-inspector Venkata Subbaiah said no case was registered as the family refused to lodge a complaint. Till now, no Coronavirus case has been reported in Andhra Pradesh and Telangana.