Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.
However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.
New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.
The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.
It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.
"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.
As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.
"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.
"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.
To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.
At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.
Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.
In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.
They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.
Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.
The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.
Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.
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My dear Venki...I say that both are not same as u said.. Do u know why?
1. Sadhivi Prachi always gives her hate speech. Like kill them kick them out of India.. Salman khan amir khan.. oh khan yeh khan.. many more as u know...
2. Zakir naik says Islam is pure rest others are not a true.. He doesnt says throw, kick, kill etc etc.. If you have any doubts you check from google bhayya and make it clear.. so dont compare lion and dogs! Lion is lion and dogs are always dogs it will never become lion :D
Zakeer Naik has more Fans - Hindus, Christians than Muslims.
His Fans are mostly highly educated, intellectuals.
He never advocates hatreds, animosities. He says truth which are wrongly practiced not following their own respective scripts like Veda, Geethas.
His knowledge in Hindu scripts are more than any common Swamees, pandiths.
Dear venki,
Your statement shows how much innocent you are. How you can compare prachi with Zakir? Did Zakir hate any religion? he is comapring the religions. He is showing what is in hindu scripts mentioned and what you are practising. Example, in vedas it clearly mention that idol worship should not be done. How many of us worshipping Idol? Did Prachi talk about Veda any time? If you listen her speeches it is spitting venom.
He has working, serving the people even with his all wealth, without seeking any personnel benefit. He has been doing it at least last 30-35years as I know it.
It would have not taken this much time to find any irregular activity if he has been committing such.
If does not need much time to know any anti social activity.
He is very much openly operating his activities obeying all the norms.
He is more popular in Europe and US, other countries than in India.
For some people it is very much difficult to digest his popularity and his fair activities.
Unfortunately those Sanghi brothern or Sanghi sympathizers can understand that he is rescuing them from their unknown mistakes.
Whatever he is doing he is not seeking any worldly benefit.
He has a strong faith in God, his sincere efforts will be rewarded in the other permanent life (which will be after death).
Really every Indian should thank God Almighty for bestowing such sincere person.
May God help us to understand truth and Guide us.
Modi's U turn....
TRUTH PREVAILS AND FALSE WILL PERISH...ALHAMDULILLAH
ZAKIR NAIK BECOMES MORE POPULAR....IN'SHA ALLAH
CHADDIGALIGE BURNOOL BAGYA
It is UNIVERSAL truth that he is innocent and just focusing on ISLAM. May almighty bless with you good always.
It is really good news for Zakir Naik and his followers, I was sure he will come up clean as I follow him last 20 years he always support teaching of Allah and Hadees and prophet's teaching. He never criticize other religion but compares to Islam whenever there was Q&A session anybody asks the question. He respect other religion.
Best of luck ZN and continue your good work.
Where are the saffron mfs who were barking and somebody please shit in mouth......
what is the fate of that Lunatic and his associates who have been shouting from the rooftop 24x7.? Is his Time Now come to an END?
Whenever a genuine Muslim targeted almighty Allah saved them, this is enough to realize a mankind that Allah is only a creator of everything nothing else. So everybody should say in one word that \Allah Hu Akbar, La ilaha Illalah\""
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