Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.
However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.
New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.
The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.
It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.
"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.
As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.
"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.
"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.
To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.
At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.
Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.
In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.
They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.
Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.
The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.
Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.
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Ram Naik India is not belongs to you there is a COMMON constitution to
all INDIANS. The seat which you holding is a respective ONE. Don't misuse or try to pollute. If you people not respecting the constitution then your same policy will destroy you.
cheddis are missing here also....
O armed cheddis show u r stamina against most wanted BABA's..
Beliye Eddu Hola Meidanthe
Where are Mulla Mulayam, his son akilesh and their wazeer azam khan ?
and bargain king Shahi imam ? All are using minorities as vote Bank. AAP is best solution for all the problem in the current scenario.
hahahaha muah what a word rama naik ji ... saabis are burning ... obba thirdrated saying we have guts only when we have drinks .. ofcourse even their ummah gang that is ISIS , uses drugs to fight . one slum shaiekh saying one verse .. hahaha ... just 2 million millitarised jewish army , 56 muslim nations cannot do anything .. they are doing mujra infront of israel .. just imagive if hindus are millitarised ... pinkaan and gaddakke benki hatchiteevi rashtradrohi. galige .. jai sri ram ... even pakistan has 200 million muzzies and 200 nukes .. but they cannot stop drone attack from USA in their country .. pakistan claims they are the protectors of holy sights ... hahaha ... first to take weapons are jewish ,then christians now hindus along with buddhists . who wants these rogue irrtitating culture ... hara hara mahadev , arm hindus for the protection of bharath mata , which is under threat from jihadists and islamic mercnearies ...
narendra Modi govt compliments to hindu terrorist......
I request muslim organisations to provide same arm camps to all of their members...
It is the duty of Governor to maintain Law and order in co-ordination with state govt. instead it supports this kind of illegal activities.
If people are allowed to take Arms what will be the future of Inida..
It is shame to the democratic country like India and going back to the old age where there was no Law and order.
It is the Duty of the governor to maintain Law and order with co-ordination of State Govt. and instead supporting sangh parivar to violate Law and order in the name of self defense!!!
If the Ruler itself is supporting this kind of activities just imagine what will be the future of India....
terrorists are trained and government is defending it.
They only have guts to fight someone wen they drink alchohol....
Let them practice or get trained!! Remember one thing - \ Jo bhi hota hai, Manzure khuda hota hai!! Maarne wale se bachane wala bada hai wahi hamara Parwardigar hai!!"
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