Nobel 2017 season opens with medicine prize

Agencies
October 2, 2017

Stockholm, Oct 2: This year's Nobel season opens Monday with the announcement of the medicine prize, turning the page on Bob Dylan's literature prize stunner that stole the spotlight in last year's award season.

Like every year, speculation is rife about the possible winners, given the number of worthy laureates in the fields of medicine, physics, chemistry, literature, peace and economics.

The Nobel medicine prize committee at the Karolinska Institute is first out to announce its choice of laureates, on Monday at 11:30 am (0930 GMT) at the earliest.

Sweden's newspaper of reference, Dagens Nyheter, suggested American oncologist Dennis Slamon could be honoured for his research on breast cancer and the drug treatment Herceptin.

Or possibly American James Allison, a pioneer in the field of immunotherapy that combats cancer cells and the winner of the 2015 Lasker Prize -- often considered the US equivalent of a Nobel medicine prize. If this method were awarded, Allison could share the prize with Arlene Sharpe and Gordon Freeman.

Meanwhile Swedish public radio SR tipped the prize could go to researchers who worked on a cure for Hepatitis C, Ralf Bartenschlager of Germany and Americans Charles Rice and Michael Sofia -- a trio also awarded the Lasker Prize, in 2016.

Waves, scissors or batteries?

The medicine prize will be followed by the physics prize announcement on Tuesday, with the discovery of gravitational waves regularly mentioned as a possible winner.

Sending ripples through space and time, gravitational waves were first predicted by Albert Einstein a century ago as part of his theory of general relativity, but the first hard evidence of their existence came only in 2015, when two US detectors found the first such signal.

That discovery could however be considered too recent by the Nobel committee.

According to Dagens Nyheter, the jury could instead choose to honour the discovery of exoplanets by Swiss astrophysicians Michel Mayor and Didier Queloz.

On Wednesday, the chemistry prize committee could give the nod to a gene-editing technique known as the CRISPR-Cas9 DNA snipping tool, a type of genetic "scissors" used to cut out a mutated gene in a human embryo and replace it by a corrected version.

But that discovery could also be too early for a Nobel, as a legal dispute rages over who discovered the technique.

It has been claimed on the one hand by the French-American research duo of Emmanuelle Charpentier and Jennifer Doudna, and on the other by Chinese-born American Feng Zhang.

Another recurring favourite for the chemistry prize is John Goodenough, a 95-year old electrochemist whose pioneering work led to the invention of rechargeable lithium ion battery present in cell phones, computers and electric cars.

Anti-nuke buzz for peace prize

Perhaps the most watched Nobel is the peace prize, the only one to be announced in Oslo and due on Friday.

This year, anti-nuclear efforts could win, some have suggested. Tensions have escalated between Washington and Pyongyang after North Korea's sixth nuclear test, and there is growing uncertainty over the Iran deal, which US President Donald Trump has threatened to tear up.

Two key orchestrators of that accord, Iranian Foreign Minister Mohammad Javad Zarif and EU foreign policy chief Federica Mogherini, are seen as strong contenders by the head of the Peace Research Institute of Oslo (Prio), Henrik Urdal.

"With North Korea also at stake, it's very important to support initiatives that guard against the development and proliferation of nuclear weapons," he said.

The names of the candidates are kept secret for at least 50 years, but those eligible to nominate candidates — including former laureates, lawmakers and government ministers around the world, and some university professors — are allowed to disclose their choices.

Those believed to be on the list include Syria's White Helmets rescue service, Congolese doctor Denis Mukwege, jailed Saudi blogger Raif Badawi and Edward Snowden, who revealed the scope of America's NSA electronic surveillance programme.

Meanwhile, the Swedish Academy has yet to set the date for its literature prize announcement, but it traditionally falls on a Thursday so October 5 and 12 are seen as possible dates.

The Academy's choice of US singer songwriter Bob Dylan last year was so divisive that Stockholm's literary circles have predicted the Academy will go for a more conservative name this year, such as Italy's Claudio Magris, Kenya's Ngugi wa Thiong'o, Canadian author Margaret Atwood or Syrian poet Adonis.

The economics prize will be announced on October 9.

This year, each Nobel comes with a nine million kronor ($1.1-million, 940,500-euro) prize sum, to be shared if several laureates are honoured in the same discipline.

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News Network
March 25,2020

Beijing, Mar 25: Around 5,000 people have signed up for the phase I clinical trial of recombinant novel coronavirus vaccine in Chinese city Wuhan where the virus first emerged late last year.

The recruitment for participants ended this week with nearly 5,000 volunteers signing up for the trial, state-run Beijing News reported on Wednesday.

A single-centre, open and dose-escalation phase I clinical trial for recombinant novel coronavirus vaccine (adenoviral vector) will be tested in healthy adults aged between 18 and 60 years, according to the ChiCTR (China Clinical Trial Register).

The trial, led by experts from the Academy of Military Medical Sciences, gained its approval on March 16 and the research is expected to last half a year.

Requiring at least 108 participants, the trial will be conducted in Wuhan, capital of Hubei province, the region worst-affected by the virus in the country, state-run China Daily reported.

Participants will experience 14-day quarantine restrictions after being vaccinated and their health condition will be recorded every day.

Chinese scientists are hastening the development of COVID-19 vaccines through five approaches --- inactivated vaccines, genetic engineering subunit vaccines, adenovirus vector vaccines, nucleic acid vaccines and vaccines using attenuated influenza virus as vectors.

So far, most teams are expected to complete preclinical research in April and some are moving forward faster, Wang Junzhi, an academician with the Chinese Academy of Engineering said.

Wang noted that research and development of COVID-19 vaccines in China is not slower than foreign counterparts and has been carried out in a scientific, standardised and orderly way.

China has stepped up the process to finalise vaccines to counter COVID-19 after Kaiser Permanente research facility in Seattle and Washington stole the march and began human trials.

China lifted tough restrictions on the Hubei province on Wednesday after a months-long lockdown as the country reported no new domestic cases.

But there were another 47 imported infections from overseas, the National Health Commission said. In total, 474 imported infections have been diagnosed in China -- mostly Chinese nationals returning home.

Comments

Y UDAYA CHANDAR
 - 
Monday, 13 Apr 2020

Dear Sir,

 

I am 77 but a very healthy person with remarkable immunity. I contracted Malaria fever in 1994 because of mosquito biting and I have not been sick anytime there after, not even for ordinary fever in the last 26 years.

 

I am sure you would like to conduct the trials on persons of varying criteria. I am sure you don't want to carry out the trials on perfectly healthy young individuals only. 

 

I am certain that  you want to try the vaccine on a 'common man' from 'general public.' I am ready for the trial and you can take me. I will be delighted. 

 

If you are not handling this matter kindly forward this mail to the correct agency.

 

I look forward to hearing from you.

 

Best regards.

 

If you are not moving forward, you are really moving backward.

Y Udaya Chandar

 

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News Network
April 11,2020

Apr 11: The number of global coronavirus deaths has increased to 102,753, while the total number of cases worldwide has surpassed 1.6 million, according to the latest update by the Washington-based Johns Hopkins University.

As of Saturday morning, the overall number of infections increased to 1,698,416, while the tally of those who recovered from the deadly disease stood at 376,677, according to the varsity's Center for Systems Science and Engineering (CSSE).

In terms of cases, the US had the highest in the world at 501,301, followed by Spain 158,273, Italy 147,577 and France 125,931.

Italy accounted for the highest death toll at 18,849, with the US in the second place with 18,769 fatalities.

Other countries with more than 10,000 deaths include Spain (16,081) and France (13,197).

Although the pandemic originated in China last December, it now only accounts for 3,343 deaths with 83,003 confirmed cases.

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Agencies
June 10,2020

Houston, Jun 10: George Floyd was fondly remembered Tuesday as “Big Floyd” — a father and brother, athlete and neighborhood mentor, and now a catalyst for change — at a funeral for the black man whose death has sparked a global reckoning over police brutality and racial prejudice.

More than 500 mourners wearing masks against the coronavirus packed a Houston church a little more than two weeks after Floyd was pinned to the pavement by a white Minneapolis police officer who put a knee on his neck for what prosecutors said was 8 minutes and 46 seconds.

Cellphone video of the encounter, including Floyd’s pleas of “I can’t breathe,” ignited protests and scattered violence across the U.S. and around the world, turning the 46-year-old Floyd — a man who in life was little known beyond the public housing project where he was raised in Houston’s Third Ward — into a worldwide symbol of injustice.

“Third Ward, Cuney Homes, that’s where he was born at,” Floyd’s brother, Rodney, told mourners at the Fountain of Praise church. “But everybody is going to remember him around the world. He is going to change the world.”

The funeral capped six days of mourning for Floyd in three cities: Raeford, North Carolina, near where he was born; Houston, where he grew up; and Minneapolis, where he died. The memorials have drawn the families of other black victims whose names have become familiar in the debate over race and justice — among them, Eric Garner, Michael Brown, Ahmaud Arbery and Trayvon Martin.

After the service, Floyd’s golden casket was taken by hearse to the cemetery in the Houston suburb of Pearland to be entombed next to his mother, for whom he cried out as he lay dying. A mile from the graveyard, the casket was transferred to a glass-sided carriage drawn by a pair of white horses. A brass band played as his casket was taken inside the mausoleum.

Hundreds of people, some chanting, “Say his name, George Floyd,” gathered along the procession route and outside the cemetery entrance in the mid-90s heat.

“I don’t want to see any black man, any man, but most definitely not a black man sitting on the ground in the hands of bad police,” said Marcus Brooks, 47, who set up a tent with other graduates of Jack Yates High School, Floyd’s alma mater.

In the past two weeks, amid the furor over Floyd’s death, sweeping and previously unthinkable things have taken place: Confederate statues have been toppled, and many cities are debating overhauling, dismantling or cutting funding for police departments. Authorities in some places have barred police from using chokeholds or are otherwise rethinking policies on the use of force.

Dozens of Floyd’s family members, most dressed in white, took part in the four-hour service. Grammy-winning singer Ne-Yo was among those who sang.

The mourners included actors Jamie Foxx and Channing Tatum, J.J. Watt of the NFL’s Houston Texans, rapper Trae tha Truth, Rep. Sheila Jackson Lee, Houston Police Chief Art Acevedo and Houston Mayor Sylvester Turner, who brought the crowd to its feet when he announced he will sign an executive order banning chokeholds in the city.

“I know you have a lot of questions that no child should have to ask, questions that too many black children have had to ask for generations: Why? Why is Daddy gone?” former Vice President Joe Biden, the Democratic presidential candidate, said, addressing Floyd’s 6-year-old daughter in a video eulogy played at the service. “Now is the time for racial justice. That’s the answer we must give to our children when they ask why.”

Biden made no mention of his opponent in November. But other speakers took swipes at President Donald Trump, who has ignored demands to address racial bias and has called on authorities to crack down hard on lawlessness.

“The president talks about bringing in the military, but he did not say one word about 8 minutes and 46 seconds of police murder of George Floyd,” said the Rev. Al Sharpton, the civil rights activist. “He challenged China on human rights. But what about the human right of George Floyd?”

Most of the pews were full, with relatively little space between people.

“So much for social distancing today,” the Rev. Remus Wright told mourners, gently but firmly instructing those attending to wear face masks.

Texas has no limit on how many people can gather in places of worship during the pandemic, though Republican Gov. Greg Abbott has encouraged churches to follow federal health guidelines.

Although the church service was private, at least 50 people gathered outside to pay their respects.

“There’s a real big change going on, and everybody, especially black, right now should be a part of that,” said Kersey Biagase, who traveled more than three hours from Port Barre, Louisiana, with his girlfriend, Brandy Pickney. They wore T-shirts printed with Floyd’s name and “I Can’t Breathe.”

Floyd served nearly five years in prison for robbery with a deadly weapon before becoming a mentor and a church outreach volunteer in Houston. He moved to Minnesota several years ago through a program that tried to change men’s lives by helping them find work in new settings.

At the time of his death, Floyd was out of work as a bouncer at a Minneapolis club that had closed because of the coronavirus outbreak. He was seized by police after being accused of passing a counterfeit $20 bill at a convenience store.

Four Minneapolis officers were arrested in his death: Derek Chauvin, 44, was charged with second-degree murder. J. Alexander Kueng, Thomas Lane and Tou Thao were charged with aiding and abetting. All four could get up to 40 years in prison.

Some of the mostly peaceful demonstrations that erupted after Floyd’s death were marked by bursts of arson, assaults, vandalism and smash-and-grab raids on businesses, with more than 10,000 people arrested. But protests in recent days have been overwhelmingly peaceful.

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