North Korea continues to develop nukes: UN report

Agencies
August 5, 2018

Washington D.C, Aug 5: Despite North Korean leader Kim Jong-un vowing to give up developing nuclear weapons and ballistic missiles, a confidential report by the United Nations revealed that the country is reportedly continuing to pursue its nuclear weapons programme.

CNN quoted a confidential UN report stating that North Korea has flouted all the sanctions put on the country and is pursuing the selling of conventional weapons to fuel violence.

The report underlined that Pyongyang continued to breach financial sanctions and arms embargo as well.

Last week, a US official also stated that North Korea is reportedly constructing new intercontinental ballistic missiles (ICBMs) and its missile programme is doing "business as usual."

On a related note, US Secretary to State Mike Pompeo who is currently attending the Association of Southeast Asian Nations (ASEAN) summit in Singapore said that he believed in pressurising Pyongyang as the country had still not made any strong efforts for the denuclearisation of the Korean Peninsula.

Another US official was quoted by Fox News as saying that there was "no evidence" that Pyongyang stopped its work of building missiles, despite dismantling a nuclear test site recently.

Last week Pompeo told a Senate panel that Pyongyang was continuing to produce fissile material required for building nuclear warheads.

The Washington Post first reported that Pyongyang was likely building two ICBMs at the same facility, where the country had made its first long-range missiles, including the Hwasong-15, having the capacity of striking the US East Coast, satellite images showed.

Pompeo, who visited North Korea for denuclearisation talks last month, had invited furore from Pyongyang, which later expressed its disappointment over the attitude of US officials on denuclearisation, calling it "regrettable and really disappointing."

In a statement by an unnamed foreign ministry spokesman, carried by North's Korean Central News Agency (KCNA), Pyongyang criticised Washington D.C. for "seeking unilateral and forced and "gangster-like demand for denuclearisation", Yonhap News Agency reported.

"The US just came out with such unilateral, robber-like denuclearisation demands as CVID (complete, verifiable and irreversible dismantlement), declaration and verification that go against the spirit of the North Korean-US summit meeting," the spokesperson said.

It is to be noted that North Korea has become a virtual pariah in the international community since the UN imposed tough sanctions on the country, after conducting nuclear tests and launching three ICBMs last year.

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News Network
May 7,2020

Islamabad, May 7: Pakistan's COVID-19 cases have crossed 24,000 after 1,523 new infections were detected, while the death toll has jumped to 564 with 38 more people succumbing to the coronavirus, health officials said on Thursday.

Even as the country is seeing an increase in the number of coronavirus cases and fatalities, Prime Minister Imran Khan will discuss the easing of lockdown restrictions with his top aides on Thursday.

The Ministry of National Health Services said that out of the 24,073 total cases, Punjab reported 9,077, Sindh 8,640, Khyber-Pakhtunkhwa 3,712, Balochistan 1,495, Islamabad 521, Gilgit-Baltistan 388 and Pakistan-occupied Kashmir 76 cases.

After 38 more deaths on Wednesday, the total coronavirus patient death toll jumped to 564. Another 6,464 have recovered. A total of 1,523 new patients were added in a single day, the ministry.

So far, 244,778 tests have been conducted, including 12,196 in the last 24 hours, it said.

Prime Minister Khan will chair the National Coordination Committee (NCC) meeting on easing the lockdown restrictions in the country. The meeting will be attended by all chief ministers.

The issue was debated in the National Command and Operation Centre (NCOC) on Wednesday and in the Cabinet on Tuesday.

Planning Minister Asad Umar said that different proposals to allow certain businesses to open were prepared and will be presented before the Prime Minister for a final decision.

Earlier, Khan, undeterred by the mounting number of deaths and the new cases, announced that he was against a lockdown as it hits the poor people badly.

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News Network
February 27,2020

Dubai, Feb 27: Twenty two people have died so far from the new coronavirus in Iran, the official Iranian news agency IRNA reported in a chart it published on Thursday.

The number of people diagnosed with the disease is 141, the chart showed. It did not specify whether those who have died were included in the tally of those infected.

Iranian officials on Wednesday reported a total of 139 cases of coronavirus and 19 deaths.

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News Network
April 10,2020

Melbourne, Apr 10: Scientists have identified six drug candidates from more than 10,000 compounds that may help treat COVID-19.

The research, published in the journal Nature, tested the efficacy of approved drugs, drug candidates in clinical trials and other compounds.

"Currently there are no targeted therapeutics or effective treatment options for COVID-19," said Professor Luke Guddat from the University of Queensland in Australia.

"In order to rapidly discover lead compounds for clinical use, we initiated a programme of high-throughput drug screening, both in laboratories and also using the latest computer software to predict how different drugs bind to the virus," Guddat said.

The project targeted the main COVID-19 virus enzyme, known as the main protease or Mpro, which plays a pivotal role in mediating viral replication, the researchers said.

This makes it an attractive drug target for this virus, and as people don't naturally have this enzyme, compounds that target it are likely to have low toxicity, they said.

"We add the drugs directly to the enzyme or to cell cultures growing the virus and assess how much of each compound is required to stop the enzyme from working or to kill the virus. If the amount is small, then we have a promising compound for further studies," said Guddat.

After assaying thousands of drugs, researchers found of the six that appear to be effective in inhibiting the enzyme, one is of particular interest.

"We're particularly looking at several leads that have been subjected to clinical trials including for the prevention and treatment of various disorders such as cardiovascular diseases, arthritis, stroke, atherosclerosis and cancer," Guddat said.

Researchers said compounds that are already along the pipeline to drug discovery are preferred, as they can be further tested as antivirals at an accelerated rate compared to new drug leads that would have to go through this process from scratch.

"With continued and up-scaled efforts we are optimistic that new candidates can enter the COVID-19 drug discovery pipeline in the near future," Guddat said.

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