Obesity and mental health woes go hand-in-hand: Study

Agencies
April 28, 2019

Apr28: Obesity and emotional problems, such as feelings of low mood and anxiety, tend to develop hand-in-hand from as young as age 7 years, according to new research.

The study was presented in the meeting, the European Congress on Obesity.

The nationwide study comparing over 12,000 Swedish children who had undergone obesity treatment with more than 60,000 matched controls found that girls with obesity were 43 per cent more likely to develop anxiety or depression compared to their peers in the general population. Similarly, boys with obesity faced a 33 per cent increased risk for anxiety and depression compared to their counterparts.

"We see a clear increased risk of anxiety and depressive disorders in children and adolescents with obesity compared with a population-based comparison group that cannot be explained by other known risk factors such as socioeconomic status and neuropsychiatric disorders", said Louise Lindberg, who led the research.

"These results suggest that children and adolescents with obesity also have an increased risk of anxiety and depression, something that healthcare professionals need to be vigilant about," added Lindberg.

Anxiety and depression are reported to be more common in children with obesity than in children of normal weight, but it is unclear whether the association is independent of other known risk factors.

To provide more evidence, researchers conducted a nationwide population-based study to investigate whether obesity is an independent risk factor for anxiety or depression.

About 12,507 children aged between 6-17 years from the Swedish Childhood Obesity Treatment Register between 2005 and 2015 were compared to 60,063 controls from the general population matched for sex, year of birth, and living area.

The research team adjusted for a range of factors known to affect anxiety and depression including migration background, neuropsychiatric disorders, parental psychiatric illness, and socioeconomic status.

A total of 4,230 children and adolescents developed anxiety or depression over an average of 4.5 years.

Obesity was clearly linked with a higher risk of anxiety and depression in childhood and adolescence. Girls (11.6 per cent vs 6.0 per cent) and boys (8.0 per cent vs 4.1per cent) with obesity were more likely to be diagnosed with anxiety and depression than those in the general population over the study period.

In further analyses, excluding children with neuropsychiatric disorders or a family history of anxiety or depression, the risks were even higher. In particular, boys with obesity were twice as likely to experience anxiety or depression as their normal-weight peers- whilst girls with obesity were 1.5 times more likely to experience anxiety and depression.

"Given the rise of obesity and impaired mental health in young people, understanding the links between childhood obesity, depression and anxiety is vital", said Lindberg.

"Further studies are needed to explain the mechanisms behind the association between obesity and anxiety/depression," Lindberg added.

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News Network
February 12,2020

Washington, Feb 12: People who are optimistic may contribute to the health of their partners, staving off the risk factors leading to Alzheimer's disease, dementia and cognitive decline as they grow old together, according to a study.

The research, published in the Journal of Personality, followed nearly 4,500 heterosexual couples from the US Health and Retirement Study for up to eight years.

The researchers found a potential link between being married to an optimistic person and preventing the onset of cognitive decline, due to a healthier environment at home.

"We spend a lot of time with our partners.They might encourage us to exercise, eat healthier or remind us to take our medicine," said William Chopik, an assistant professor at the Michigan State University in the US.

"When your partner is optimistic and healthy, it can translate to similar outcomes in your own life. You actually do experience a rosier future by living longer and staving off cognitive illnesses," Chopik said.

An optimistic partner may encourage eating healthy foods, or working out together to develop healthier lifestyles, the researchers said.

For example, if a person quits smoking or starts exercising, their partner is close to following suit, they said.

"We found that when you look at the risk factors for what predicts things like Alzheimer's disease or dementia, a lot of them are things like living a healthy lifestyle," Chopik said.

"Maintaining a healthy weight and physical activity are large predictors.There are some physiological markers as well. It looks like people who are married to optimists tend to score better on all of those metrics," he said.

The researchers said there is a sense where optimists lead by example, and their partners follow their lead.

They also suggest that when couples recall shared experiences together, richer details from the memories emerge.

Chopik noted while there is a heritable component to optimism, there is some evidence to suggest that it's a trainable quality.

"There are studies that show people have the power to change their personalities, as long as they engage in things that make them change," Chopik said.

"Part of it is wanting to change. There are also intervention programs that suggest you can build up optimism," he added.

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Agencies
May 26,2020

Tedros Adhanom Ghebreyesus, the World Health Organisation's (WHO) Director-General, said that a clinical trial of hydroxychloroquine (HCQ) on COVID-19 patients has come to "a temporary pause", while the safety data of the the anti-malaria drug was being reviewed.

According to the WHO chief, The Lancet medical journal on May 22 had published an observational study on HCQ and chloroquine and its effects on COVID-19 patients that have been hospitalized, reports Xinhua news agency.

The authors of the study reported that among patients receiving the drug, when used alone or with a macrolide, they estimated a higher mortality rate.

"The Executive Group of the Solidarity Trial, representing 10 of the participating countries, met on Saturday (May 23) and has agreed to review a comprehensive analysis and critical appraisal of all evidence available globally," Tedros said in a virtual press conference on Monday.

The review will consider data collected so far in the Solidarity Trial and in particular robust randomized available data, to adequately evaluate the potential benefits and harms from this drug, he said.

"The Executive Group has implemented a temporary pause of the HCQ arm within the Solidarity Trial while the safety data is reviewed by the Data Safety Monitoring Board. The other arms of the trial are continuing," Tedros added.

WHO initiated the Solidarity Trial, a plan to evaluate the safety and efficacy of four drugs and drug combinations against COVID-19 more than two months ago, which include HCQ.

According to the WHO, over 400 hospitals in 35 countries are actively recruiting patients and nearly 3,500 patients have been enrolled from 17 countries under the Solidarity Trial.

Tedros added that the safety concern over the drug related only to the use of HCQ and chloroquine in COVID-19, and "these drugs are accepted as generally safe for use in patients with autoimmune diseases or malaria".

"WHO will provide further updates as we know more," he added.

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