Obesity, here’s one surprising everyday habit that puts you at great risk

Agencies
May 22, 2018

May 22: Removing your shoes when entering the house can help you stay slim as it prevents hormone-altering chemicals from accumulating indoors, a study suggests.

Obesity increasingly affects millions of people worldwide, with cases rising sharply in young children and babies - a trend which is not explained by evolving diets and lifestyles alone.

Chemicals that interfere with how our bodies store and process fat are referred to as ‘obesogens’, and have been suggested as a possible contributor to the increasing number of obesity cases.

Researchers from the University of Aveiro and University of Beira Interior in Portugal reviewed existing studies, and showed that the most important sources of exposure to obesogens indoors are diet, house dust, and everyday products such as cleaning chemicals, kitchenware or cosmetics.

Diet samples in some of the studies showed, for example, that obesogens such as tributyltin - a chemical in anti-fouling paint banned a decade ago, and cadmium - a metal widespread in the environment associated with certain cancers, can still be found in food products, in some cases at high concentrations.

“Obesogens can be found almost everywhere, and our diet is a main source of exposure, as some pesticides and artificial sweeteners are obesogens,” said said Ana Catarina Sousa, from University of Lisbon in Portugal.

“Equally, they are present in plastics and home products, so completely reducing exposure is extremely difficult - but to significantly reduce it is not only feasible, but also very simple,” said Sousa.

Based on the findings of the review, the researchers suggest removing shoes when entering the house to avoid bringing in contaminants in the sole of shoes, vacuuming often, and minimising carpets at home or work.

Researchers also recommend people to choose fresh food over processed products and buying organic fruit and vegetables produced without pesticides.

Further studies are needed in order to provide unequivocal evidence of how obesogens contribute to the obesity epidemic.

“These are baby steps to achieve an obesogen-free lifestyle but a really good start. Essentially, watch your diet and get rid of the dust at home,” Sousa said.

“Adults ingest about 50 milligrammes of dust every day, and children twice as much, so keeping the house clean is a very effective measure. And use a humid cloth to dust your furniture, rather than a cleaning product that may contain more of these chemicals,” she said.

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Agencies
February 23,2020

Los Angeles, Feb 23: According to researchers, if administered quickly, a common medication that reduces bleeding could be a treatment for bleeding stroke.

The Spot Sign and Tranexamic Acid on Preventing ICH Growth - Australasia Trial (STOP-AUST) was a multicenter, prospective, randomized, double-blind, placebo-controlled, phase 2 clinical trial using the antifibrinolytic agent tranexamic acid in people with intracerebral hemorrhage (ICH).

ICH is a severe form of acute stroke with few treatment options.

Tranexamic acid is currently used to treat or prevent excessive blood loss from trauma, surgery, tooth removal, nosebleeds and heavy menstruation. For this study, one hundred patients with active brain bleeding were given either intravenous tranexamic acid or placebo within 4.5 hours of symptom onset.

Researchers analyzed brain CT scans taken during the 24-hour period after treatment with tranexamic acid or placebo.

Researchers found a trend towards reduced hemorrhage expansion in the group treated with tranexamic acid, especially in those treated within 3 hours of the brain bleed. However, this trend was not statistically significant. The finding was consistent with previous research using the medication.

"Further trials using tranexamic acid are ongoing and focusing on ultra-early treatment - within 2 hours. 

This is where the greatest opportunity for intervention appears to be. Tranexamic acid is inexpensive, safe and widely available. Our results and others provide great impetus for further, focused research using this treatment," Nawaf Yassi said.

Larger trials focused on patient outcomes are required for this therapy to enter routine clinical practice.

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Agencies
May 2,2020

Clinician-scientists have found that Irish patients admitted to hospital with severe coronavirus (COVID-19) infection are experiencing abnormal blood clotting that contributes to death in some patients.

The research team from the Royal College of Surgeons in Ireland found that abnormal blood clotting occurs in Irish patients with severe COVID-19 infection, causing micro-clots within the lungs.

According to the study, they also found that Irish patients with higher levels of blood clotting activity had a significantly worse prognosis and were more likely to require ICU admission.

"Our novel findings demonstrate that COVID-19 is associated with a unique type of blood clotting disorder that is primarily focussed within the lungs and which undoubtedly contributes to the high levels of mortality being seen in patients with COVID-19," said Professor James O'Donnell from St James's Hospital in Ireland.

In addition to pneumonia affecting the small air sacs within the lungs, the research team has also hundreds of small blood clots throughout the lungs.

This scenario is not seen with other types of lung infection and explains why blood oxygen levels fall dramatically in severe COVID-19 infection, the study, published in the British Journal of Haematology said.

"Understanding how these micro-clots are being formed within the lung is critical so that we can develop more effective treatments for our patients, particularly those in high-risk groups," O'Donnell said.

"Further studies will be required to investigate whether different blood-thinning treatments may have a role in selected high-risk patients in order to reduce the risk of clot formation," Professor O'Donnell added.

According to the study, emerging evidence also shows that the abnormal blood-clotting problem in COVID-19 results in a significantly increased risk of heart attacks and strokes.

As of Friday morning, the cases increased to 20,612 cases in Ireland, with 1,232 deaths so far, according to the Johns Hopkins University.

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Agencies
February 6,2020

Researchers have found the rates of lung cancer are higher in young women than men.

The study, published in the journal Pediatrics, examined lung cancer rates in young adults in 40 countries across five continents and uncovered a trend of higher lung cancer rates in women compared with men in recent years.

The emerging trend was widespread, affecting countries across varied geographic locations and income levels.

The changes appeared to be driven by a rising rate of adenocarcinoma lung cancer among women, said the study researchers from University of Calgary in Canada.

Lung cancer rates have been higher among men than women because men started smoking in large numbers earlier and smoked at higher rates; however, recent studies have reported converging lung cancer incidence rates between sexes.

Among men, age specific lung cancer incidence rates generally decreased in all countries, while in women the rates varied across countries with the trends in most countries stable or declining, albeit at a slower pace compared to those in men.

For the findings, lung and bronchial cancer cases between 30-64 age group from 1993-2012 were extracted from cancer incidence in five continents.

The study found the higher emerging rates of lung cancer in young women compared to young men.

According to the researchers, future studies are needed to identify reasons for the elevated incidence of lung cancer among young women.

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