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Bengaluru, Mar 30: The total number of COVID-19 cases in Karnataka has climbed to 88 on Sunday after five more persons tested positive for the lethal infection.

"Five more COVID-19 cases reported in Karnataka taking positive cases in the state to 88," said the State health department.

Of the five, one is a close contact of an earlier confirmed patient and the others are workers of a pharmaceutical company in Mysuru, from where a person had tested positive, the department said.

The country is under a 21-day lockdown to prevent the spread of coronavirus, which according to the Ministry of Health and Family Welfare, has infected 1,071 people so far.

May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.

According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.

"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.

They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.

Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.

"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.

"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.

In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.

"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.

The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.

These children were then confirmed to have COVID-19.

While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.

Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.

According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.

"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.

Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.

While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.

However, he cautioned that more research is needed to confirm their findings.

"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.

Bengaluru, Jul 25: Kalmane Kamegowda, the lake man who was recently praised by Prime Minister Narendra Modi during a recent Mann Ki Baat, is in serious condition after he tested positive for COVID-19, former Karnataka Chief Minister HD Kumaraswamy said on Saturday.

"The health condition of Lake Kamegowda is serious. It is our responsibility to save him. I demand that the state government make appropriate arrangements for emergency treatment," Kumaraswamy tweeted.

"The Prime Minister also praised him in Mann Ki Baat. Chief Ministers expressed appreciation. Only praising doesn't help him at this point of time. The government needs to come forward to treat him in a good hospital when he's sick," he said in the following tweet.

Kamegowda of Dasanadoddi village in Malavalli taluk had drawn the attention of the Prime Minister in the 66th 'Mann Ki Baat' for constructing ponds to conserve rainwater during the summer.

Responding to Kumaraswamy's remark, State Medical Education Minister Dr Sudhakar K said that he has already called up the Mandya Medical College and directed the hospital to admit and treat Kamegowda.

"As soon as I noticed the seriousness of Kamagowad's health, I called the director of the Mandya Medical College and informed him that he should be admitted to the hospital and treated. I pray to the Lord that the Kamagowadas who inspire the whole country will heal soon," Sudhakar K tweeted.