Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.
However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.
New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.
The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.
It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.
"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.
As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.
"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.
"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.
To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.
At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.
Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.
In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.
They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.
Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.
The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.
Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.
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Wow just in 9 mins the fire service reaches!!!
The biggest blunder of Modi Government....those who eat beef let them eat it....those who do not with all respect do not eat it....its their choice.....vote bank politics...that should be stopped for once and for all....
Muslims do not eat pig....but do not disturb Christians at all...
Masha allah our great leaders. may Allah give you long life.
incredible India.. The government, high commissioners getting a warning by RSS Terrorists but no action till date and if it is said by Muslim outfits they will name it as terrorism and file case against innocents.
Now impose case against these goondas and let's see how they will react..
If These terrorists warns means don't worry. If they strike and do any other terrorist acts, then shoot them. Automatically Dakshina kannada will become peaceful district like before.
NIA It is Narendra Interests adopting Agency.
They killed karkera, Good police inspectors everywhere Ex. Bathla house attack, etc.
They are arresting whomever opposing RSS and their Terrorist organizations.
and Why not BJP ????????
its unfortunate that ...he included SDPI as a communal group ....its a POLITICAL party ...just because fighting for the rights of minorities and dalits . and killed by RSS government is adding and considering as communal parties ????????????????
RAI , UT and LOBO are behind this to add SDPI too in this list ...
and one more thing is that ... victim of RSS are all including RSS members ( some times RSS kills their own members to shut the mouth) .....now when RSS started to kill civilians in DK and NK....and Popular front started to protest against the same ....now govt added victims in the list to target ...
all though the RSS is the main cause for all ....only RSS should be targeted not PFI or SDPI
All drama baazi...
assalam alikum wa rahmatullahi wabarkatuhu,
mai hajiyoki tahe dil se khidmath karna chahatahu,please muje ek moukha de allah meri dil ki muraad puri kare ..AMEEN...
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Asslumalikum waRahmatullahi Wabarkatuhu.
Sir
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Good move,book all anti social elements for peaceful atmosphere in DK and Udupi, Let normal people live peacefully
first Police is showing its presence .....who were dead while processions and stone pelting by BD and other third class organizations .....
in fact Muslims dont pelt the stones or cow heads ...we have seen this in Shimoga and other places and as well as Bantwal ..where a viral video shows the reality ....
if P.O.L.I.C.E over come from its % pressure , then we can see some light of peace in the district .....
Asslamoalykum
Sir I have Ready passport and I am very excited to do khidmaat e hujjaze Kiran but I want you to pay money but I promise to you when I earn some money I will return your money. Thank you
Please
Well done police. Should punish this gundaas.
When Muslims do their job taught by prophet Muhammad pbuh ... EXPECT ALLAHs help. Never lose trust in ALLAH..
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