Ponzi scam: SIT arrests IMA auditor Iqbal Khan

Bengaluru, Mar 28: Sun Tsu, in 'The Art of War' speaks of a skilful general who can subdue his enemy without any fighting. This constitutes the ultimate triumph which is referred to as stratagem. Today, we would need one such when we are faced with the '21-day corona challenge' for India.
Nearly four weeks back, Dr Jyothsna Rao, Dr Gururaj Rao and I sat across the OPD in the afternoon at HCG Bengaluru discussing our ongoing cancer immunology research. While on this topic, we drifted into the discussion on the coronavirus. During this engaging discussion, we wondered the similarity of the enigma between the virus and cancer. I paused to ask Dr Jyothsna and Dr Guru - how we wish we could do something against this virus.
Dr Jyothsna is a PhD from NCBS and had worked under Dr Ralph Steinman, physician and researcher from Rockefeller University, who won the Nobel Prize for his discovery of the dendritic cell and its role in adaptive immunity in 2011. Dr Gururaj is a molecular and cell biologist who did his PhD at the Chapel Hill, University of North Carolina and is the Director of iCrest.
Jyothsna while hearing our perplexing conversation on the covid intervened, "Yes, surely. I think we should take a break from cancer and focus on the innate and adaptive immunity role in COVID-19."
Thus began this sincere attempt to relook the human immune system from the eyes of the COVID-19.
We have 10 types of immune cells at the least which are widely dispersed in millions across the body. When our body is invaded by a foreign organism (bacteria, fungi or virus), these cells work with each other to destroy the invader.
Now, the question is - how do the immune cells talk to each other? They use small-molecule substances called cytokines (cyto means cells; kine means movement). There are many cytokines that are involved in work on the immune system. The most relevant for viruses are interferons.
Interferons (IFN) as the name reflects have an ability to interfere with the viral activity and stop their multiplication. These specialised signal proteins are released by our cells in response to a viral attack to forewarn other cells. They help build the antiviral proteins within the cells to kill the virus as it tries to invade the new cells.
Historically, interferons are a group of cytokines known to be potent antiviral agents against viruses and a hallmark cytokine induced by the host upon viral infections. Interferons possess unique immunoregulatory activities and are signature cytokines released by (TH1) T immune cells, which are crucial in viral infections.
As the outbreak of COVID-19 grapples us, an urgent need for finding strategies to combat the virus is growing. Coronaviruses (CoVs) are a group of RNA viruses. In patients infected with coronavirus, it was indicated that the activation of the IFN does not occur until 48 hours post-infection. Thus the delayed IFN-related antiviral response by the healthy cells leads to coronavirus evade the immune response.
Numerous studies have presented the success in defeating CoVs by the direct administration of IFNs. In a combination as a concoction, it was shown to synergistically inhibit the virus replication in vitro.
Moreover, it is understood that the earlier induction of IFNs in children although they have a less developed immune system could be the reason behind the children being least affected.
The key to success in reducing the disease fatality might be the stimulation of the immune responses to trigger IFN production at the very early stages of the disease, which might be done through the administration of IFN. Despite the evidence for the efficacy of IFNs in treating CoV-induced infections, the proper dosing and ideal timing for such interventions needs to be verified in clinical trials.
For the later stages of the diseases in advance stages where patients are on ventilator and have developed respiratory distress, we propose to utilise the mesenchymal cells derived from donor bone marrow that have been known to treat acute respiratory syndrome. Mesenchymal cells are known to possess anti-inflammatory activity and thus used often in autoimmune diseases.
With this scientific background, we have activated T cells from healthy donors, in a cGMP facility at iCrest - HCG hospital with an enriched cocktail of cytokines rich in Interferons. Injections of this cocktail we believe will result in a surge of cytokines in the body of the infected person and will boost his ability to fight the virus in the early phases. We are in the initial phases of this study and hope to be ready in the coming weeks with meaningful data on its potential utility.
Currently, it awaits government approvals (Union and state) and we have applied to central drugs authority for their initial evaluation and further directions.
As my Guru often expounded the philosophy of 'Seva' - the goal of education is knowledge, the end goal of knowledge is service. In this attempt to serve our fellow humans at this brink of unprecedented crisis, medical fraternity stands with you and promises to do our best for your safety.
We assure to exhaust every bit of our spirit in this fight against coronavirus. We have lost the sight of shores and travelled thus far, but that is the mandatory first step to cross the ocean. Are we going to succeed in this battle, is something only time will answer. 

Belgaum, Mar 26: The police on Thursday thrashed people who had gone to offer prayers at a mosque despite the nationwide lockdown in force.
In a video, the police personnel can be seen thrashing the people with batons while they were leaving after offering prayers at a local mosque here.
In another incident in Rajasthan's Pratapgarh, the police made few youngsters hop along a road and even gave the 'murga,' punishment to a few of them for violating the restrictions.
Similarly in Uttar Pradesh's Budaun, the police made people hop along a road with their bags strapped on their backs as a punishment. The people were possibly going to their native places.
In the video of the Budaun incident, a few men can be seen being made to hop along the road with a stick-wielding policeman keeping a watch.
SSP Budaun told ANI that an investigation is being conducted into the incident and expressed an apology for the police's behaviour.
Prime Minister Narendra Modi had announced a 21-day countrywide lockdown to check the spread of coronavirus, saying that "social distancing" is the only option to deal with the highly contagious disease.

Mangaluru, Jan 9: Noted city based tax accountant and former Rotary District Governor Surya Prakash Bhat passed away late this evening following brief illness. He was 62 and is survived by his wife Srimathi and two daughters Shruthi and Shravya.

Surya Prakash Bhat suddenly fell ill and had been in coma for the last two weeks due to complications arising from acute diabetes. He was undergoing treatment in the ICU at Yenepoya Hospital, Kodialbail. However he failed to respond to treatment and passed away at 9.20 p.m on Wednesday, January 8th.

He was an active Rotarian. He was an active member of Rotaract Club of Mangalore Central during his youth and then joined Rotary Club of Mangalore in 1989. After holding various positions in club level and the district level including Rotary District Secretary during the year 1995-96, he became club President of Rotary Club of Mangalore during its Golden Jubilee year in 1999-2000. Then on he rose to the position of District Governor of RI Dist. 3180 during 2003-2004. He was presently a member of the Rotary District Advisory Council.

Popularly known as "SURI", Surya Prakash Bhat was born in Mangalore on 8th May 1957. He had his early education in Milagres High School and graduated from St. Aloysius College. He did his articleship under Kamath & Rao Chartered Accountants. He has been practicing as a Tax Consultant since 1980 specializing in the fields of Goods & Service Tax (GST).

He has earlier served as Treasurer and Secretary of Kanara Chamber of Commerce & Industry, Mangalore. He also has been a Member of Finance & Banking Committee of FICCI, New Delhi; Member of Advisory Board, Department of Commercial Taxes as well as of Customs & Central Excise. He was one of the founders of The Karavali Automotive Sports Club, Mangalore and a Trustee of Shri Somanatha Temple, Someshwar, Mangalore.

Had been regularly anchoring programme like “Janadhwani”, a programme which highlights problems of common man, Elections Special and Budget Analysis in the local TV Channel.

Funeral will be held tomorrow in Mangalore.

Rotary Connection

Surya Prakash Bhat Joined Rotaract Club in 1976-77 and had won record 14 out of 15 awards in the district (Comprising of 8 Revenue Districts) as the best President during 1984-85.  He served as Rotaract District Secretary during 1985-86. 

He has been addressing various institutions, organizations and service clubs on matters of general interest, personality and individual development and Rotary. Has addressed the prestigious Rotary Institutes at Colombo and was trainer for the DGN’S at Cochin Institute, Bangkok Institute & SINGAPORE Institute. He was the President during the "Golden Jubilee Year" of Rotary Club of Mangalore during 1999-2000 when the club had bagged a record 28 awards in all.

He attended Rotary International Conventions at Singapore in 1999, at Denmark/Sweden in 2006 and New Orleans, USA in 2011,and Sydney, Australia in 2014. He was District Secretary during 1995-96 and then was the Club President during 1999-2000. He had initiated unique District Projects like “Sanjeevini” – Students Parents Insurance Scheme, “Jeeva” Highway Ambulance Project, Mid Day Meal for students of 6th & 7th Std children, Mobility Training Centre for the Blind etc. 

During the Governorship, RI Dist.3180 topped the world in membership development with 15 new clubs and 852 new members.  He has represented the Dist.3180 to Council on Legislation (decision taking body of Rotary International) at Chicago, USA during 2006-07.  Has been awarded “The Citation for Meritorious Service” by THE ROTARY FOUNDATION of Rotary International in recognition of his devoted efforts for the furthering of better understanding and friendly relations of people’s of the world. Has also been awarded “The Service above Self” citation of the Rorary International for the year 2011. Was the coordinator for Zone 6A & 6B covering around 12 countries for Literacy Programme of R.I for the year 2006-07.

Was the Chairman of the Dist. Trainers Training Programme at the Rotary Institute 2017-18 at Kuala Lampur, Malaysia.