Poojary offers 'urulu seve' seeking divine intervention in Cauvery dispute

Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.

However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.

New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.

The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.

It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.

"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.

As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.

"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.

"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.

To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.

At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.

Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.

In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.

They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.

Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.

The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.

Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.

Bantwal, Jan 11: Seven people were booked for organising protest without taking permission or intimation, police said on Saturday.

The alleged accused were identified as Nandavar Juma Masjid President Basheer, Khateeb of the Masjid Abdul Majeed Darimi, Gram Panchayath President Mohammed Shareef Nandavar, former President of Masjid Majeed, Arif Nandavar, Mustafa and Abubaker.

They have been booked for allegedly organising protest outside Nandavar Juma Masjid on Jan 10 afternoon without intimation to police or obtaining permission.

Bengaluru, Jun 6: Karnataka registered 378 Covid-19 cases in the past 24 hours, breaching the 5,000-mark to settle at 5,213, said an official, here on Saturday. "New cases reported from Friday 5 p.m. to Saturday 6 p.m. is 378," said a health official.

Of the new cases, 333 are local returnees, comprising 88 per cent of the new infections. Returnees from Maharashtra accounted for 99 per cent new cases at 329.

Majority infections in Karnataka nowadays are returnees, mostly from the state''s northern neighbour. Only 27 new infections were contacts of earlier cases.

On Saturday, cases spiked in Udupi, Kalaburagi, Yadgir, Bengaluru Urban, Belagavi, Vijayapura, Davangere and Dakshina Kannada.

Udupi witnessed the highest number of cases (121), followed by Yadgir (103), Kalaburagi (69), Dakshina Kannada (24), Bengaluru Urban (18), Vijayapura and Davangere (6 each), Belagavi (5), Gadag (4), Mandya, Hassan, Dharwad and Haveri (3 each), Raichur, Chikkaballapura and Uttara Kannada (2 each) and Bidar, Tumkur, Kolar and Koppal (1 each).

Among the new cases, three patients from Bengaluru Urban are suffering from Influenza Like Illness (ILI) and another from Severe Acute Respiratory Infection (SARI).

There were seven cases with international travel history to United Arab Emirates (UAE) and one to Turkey.

Meanwhile, 280 people were discharged in the past 24 hours and two persons succumbed to the virus, one from Bidar and another from Vijayapura. Of all the cases, 3,184 are active, 1,968 discharged, 59 dead and 11 in the ICU.

In the past 24 hours, Karnataka tested 11,862 people, of which 11,431 reports returned negative. In total, 3.72 lakh samples have been tested so far, of which 3.61 lakh have returned negative.

Currently, Udupi is leading the state''s Covid-19 burden with 785 active cases, followed by Kalaburagi (448), Yadgir (407), Raichur (320) and Mandya (163) among others.

Bengaluru Urban has accounted for 13 deaths, followed by Kalaburagi (7), Bidar, Vijayapura, Davangere and Dakshina Kannada (6 each) and Chikkaballapura (3 each), among others.