Poor diet linked to 1 in 5 deaths globally: study

Agencies
April 4, 2019

Paris, Apr 4: One in five deaths globally are linked to poor diet, experts said Thursday, warning that overconsumption of sugar, salt and meat was killing millions of people every year.

The United Nations estimates that nearly a billion people worldwide are malnourished, while nearly two billion are "overnourished".

But the latest study on global diet trends, published in The Lancet, showed that in nearly every one of the 195 countries surveyed, people were also eating too much of the wrong types of food -- and consuming worryingly low levels of healthier produce.

For example, the world on average consumes more than ten times the recommended amount of sugar-sweetened beverages, and 86 percent more sodium per person than is considered safe.

The study, which examined consumption and disease trends between 1990-2017, also cautioned that too many people were eating far too few whole grains, fruit, nuts and seeds to maintain a healthy lifestyle.

Of the 11 million deaths attributed to poor diet, by far the largest killer was cardiovascular disease, which is often caused or worsened by obesity.

"This study affirms what many have thought for several years -- that poor diet is responsible for more deaths than any other risk factor in the world," said study author Christopher Murray, director of the Institute for Health Metrics and Evaluation at the University of Washington.

"Our assessment suggests the leading dietary risk factors are high intake of sodium, or low intake of health foods."

The report highlighted large variation in diet-related deaths between nations, with the highest-risk country Uzbekistan having ten times the food-based mortality rate of the lowest-risk, Israel.

In January, a consortium of three dozen researchers called for a dramatic shift in the way the world eats.

The EAT-Lancet report said that the global population must eat roughly half as much red meat and sugar, and twice as many vegetables, fruits and nuts in order to avert a worldwide obesity epidemic and avoid "catastrophic" climate change.

Authors of Thursday's study noted that economic inequality was a factor in poor dietary choices in many countries.

It found that on average, reaching the "five-a-day" fruit and vegetable servings advocated by doctors cost just two percent of household income in rich nations, but more than a half of household income in poorer ones.

"This study gives us good evidence of what to target to improve diets, and therefore health, at the global and national level," said Oyinlola Oyebode, Associate Professor at Warwick Medical School, who was not involved in the research.

"The lack of fruit, vegetables and whole grains in diets across the world are very important -- but the other dietary factor highlighted by this study is the high intake of sodium."

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Agencies
May 2,2020

Clinician-scientists have found that Irish patients admitted to hospital with severe coronavirus (COVID-19) infection are experiencing abnormal blood clotting that contributes to death in some patients.

The research team from the Royal College of Surgeons in Ireland found that abnormal blood clotting occurs in Irish patients with severe COVID-19 infection, causing micro-clots within the lungs.

According to the study, they also found that Irish patients with higher levels of blood clotting activity had a significantly worse prognosis and were more likely to require ICU admission.

"Our novel findings demonstrate that COVID-19 is associated with a unique type of blood clotting disorder that is primarily focussed within the lungs and which undoubtedly contributes to the high levels of mortality being seen in patients with COVID-19," said Professor James O'Donnell from St James's Hospital in Ireland.

In addition to pneumonia affecting the small air sacs within the lungs, the research team has also hundreds of small blood clots throughout the lungs.

This scenario is not seen with other types of lung infection and explains why blood oxygen levels fall dramatically in severe COVID-19 infection, the study, published in the British Journal of Haematology said.

"Understanding how these micro-clots are being formed within the lung is critical so that we can develop more effective treatments for our patients, particularly those in high-risk groups," O'Donnell said.

"Further studies will be required to investigate whether different blood-thinning treatments may have a role in selected high-risk patients in order to reduce the risk of clot formation," Professor O'Donnell added.

According to the study, emerging evidence also shows that the abnormal blood-clotting problem in COVID-19 results in a significantly increased risk of heart attacks and strokes.

As of Friday morning, the cases increased to 20,612 cases in Ireland, with 1,232 deaths so far, according to the Johns Hopkins University.

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Agencies
July 4,2020

The Union health ministry on Friday revised the dosage of anti-viral drug remdesivir to be administered to coronavirus patients in the moderate stage of illness from the earlier six days to five days as it issued an updated 'Clinical Management Protocols for COVID-19'.

The drug, administered in the form of injection, should be given at a dose of 200 mg on day one followed by 100 mg daily for four days (total five days), the new treatment protocols stated.

The Health Ministry on June 13 had allowed the use of remdesivir for restricted emergency use in moderate cases under "investigational therapies".

"Under emergency use authorisation, remdesivir may be considered for patients in moderate stage requiring oxygen support," the document stated.

It is not recommended for those with severe renal impairment and high level of liver enzymes, pregnant and lactating women, and those below 12 years, it said.

The ministry also okayed off-label application of tocilizumab, a drug that modifies the immune system or its functioning, and convalescent plasma for treating COVID-19 patients in the moderate stage of illness as "investigational therapies".

It also recommended hydroxychloroquine for patients during the early course of the disease and not for critically-ill patients.

On June 27, the ministry had included an inexpensive, widely used steroid dexamethasone in treatment protocols for COVID-19 patients in the moderate to severe stages of their illness among other therapeutic measures.

The ministry advised use of dexamethasone, which is already used in a wide range of conditions for its anti-inflammatory and immunosuppressant effects, as an alternative choice to methylprednisolone for managing moderate to severe cases of coronavirus infection.

India's COVID-19 cases soared by over 20,000 in a day for the first time taking the country's total tally to 6,25,544 on Friday while the death toll climbed to 18,213 with 379 new fatalities, according to the Union Health Ministry data updated at 8 am.

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Agencies
May 30,2020

Drinking coffee may help reduce the risk of certain digestive disorders, including gallstone disease and pancreatitis, a new study has suggested.

The study from the Institute for Scientific Information on Coffee (ISIC) also highlighted other beneficial effects that coffee consumption may have on the process of digestion, including supporting gut microflora and promoting gut motility.

"Data indicates benefits against common digestive complaints such as constipation, as well as a potential reduction in the risk of more serious conditions like chronic liver diseases," said study author Carlo La Vecchia from the University of Milan in Italy.

Gallstone disease is a common digestive disorder, caused by the accumulation of gallstones in the gallbladder or bile duct, which affects approximately 10-15 per cent of the adult population.

While the mechanism by which coffee may protect against gallstone disease is not yet known, it has been observed that the risk for the condition declines with increasing daily consumption of coffee, the researchers said.

Caffeine is thought to play a role in these associations, as the same effect is not observed with decaffeinated coffee.

A common question among consumers and focus area for research is whether coffee is associated with heartburn or gastro-oesophageal reflux disease (GORD).

While a small number of studies have suggested an association between coffee drinking and GORD, the majority of studies reviewed suggest that coffee is not a major trigger of these conditions.

The report also reviewed a growing area of health and nutrition research, namely: the effect of coffee on the gut microflora (microorganism populations).

Recent studies suggest that populations of the beneficial gut bacteria Bifidobacterium spp, increase after drinking coffee.

The findings showed the dietary fibre and polyphenols found in coffee, support the healthy growth of microflora populations.

Additional research findings highlighted that coffee consumption is thought to stimulate digestion by encouraging the release of gastric acid, bile and pancreatic secretions.

Coffee is one of the most widely researched components of the diet, and its effect on digestion remains a growing area of research, the researchers noted.

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