May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.
According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.
"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.
They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.
Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.
"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.
"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.
In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.
"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.
The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.
These children were then confirmed to have COVID-19.
While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.
Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.
According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.
"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.
Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.
While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.
However, he cautioned that more research is needed to confirm their findings.
"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.
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It is pre-planned murder,,,tmrw musthafa is to be released from jail
Those who r congratulating for the murder, please go and do it by yourself and feel proud. No... you cant do and u will never do it bcoz it will spoil ur future and your family.
Yererna ammana mage jaild kuriyinda kuriyad nank daane atthe.
Be a human first
Some ppl r happy for the above news..Now kiran will meet d same fate by someone else.
Its easy to type and comment congratulating kiran, but saddna tho kiran ko hai.
Kiran wait for your turn...
This is expected.........Accused considered as culprit.......
In reality culprit ruling the nation...........
falsehood bound to persish.truth prevails.....
For a Mumin if die in the cause of Truth or win both same..... both considered as victory
Indeed great news ... tax payer money saved ,billawa youth prashanth pujari atmakke shanthi sikthu ... good job kiran ... terrorists and criminals must meet the same fate ...
Inna Lillahi wa inna ilaihi rajioon
God is great, he dispensed justice inside the jail.
60% Cops are to be considered as terrorist.
Strange, encounter in jail.......Muslims have to suffer everywhere in the name of terrorism.....
Strange, How the criminals get lethal weapons in the Jail????
why the jail is providing them entertainment channel, So, this is the reason people do not hesitate to commit crime. Because they are getting everything in the Jail and leading a lavish lives over there.
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