May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.
According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.
"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.
They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.
Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.
"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.
"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.
In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.
"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.
The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.
These children were then confirmed to have COVID-19.
While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.
Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.
According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.
"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.
Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.
While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.
However, he cautioned that more research is needed to confirm their findings.
"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.
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You people can check reports, SDPI people involved in many RSS workers' murder. They didnt get proper punishmnet
How BJP became communal..! BJP stands for patriotism. SDPI people working for conversion of people and making issues. That party should be banned fully.
Shame mr. rai. You only making the situation more complicated. By terming 'communal hub', you are injecting fear to common people.
BJP, SDPI both are communal they agreed. Should add more. BD, PFI etc
Dear Mr. Rai, with due respect, you and your party before flagging off the rally must answer the following questions to the general public!
1) you and your party won many times and even ruled undivided DK District but, why have you failed to controll the RSS and its hate campaign aginst a particular community???
2) During the last assemble election you have made public that once you got elected, you will send prabahkar bhat to jail! what action have you taken??
3) your own party worker late mr. Jaleel karopadi murdered by RSS Goons, what action and justice you have done to his father? who openly cried for justice and in anger he critisized you for failing to provide him justice!
4) under your constituency there were many muslim leaders and activists murder happend were were you that time?
5) the national tragedy of Babri masjid was demolished under congress rule and your national leadership maintained the soft hindutva, why have your party failed to protect it ..?
6) your national leadership had once said we will give justice to muslim community, and will rebuild babri masjid, being in a power for more than 10 years why your party couldnt provide the justice to the victims??? 7) your party have appointed the sri krishna commission! what action your party implimented against the hindutva brigade??
8) you and your party claims that, we are the protector of minority community! what protection you and your party provided for indian muslims?? since 70 years they have been looted, burnt alive, raped,tortured, made refugees, made scape-goat as terrors, etc etc ???
during all those time indian muslims dedicated their trust on all the so called secular partys, but all of them ditched to the community and maintained soft hindutva!
The anger, Disappointment, Frustration, and the Thawakkul on allah made to born SDPI on indian soil..!! that is the reality, that nobody cannot deny!!
Your Failure is SDPI's Stength, and SDPI's Success is indian oppressed community's success..!!
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