Rain floods Mangaluru, 4 dead; schools in DK, Udupi shut

Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.

However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.

New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.

The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.

It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.

"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.

As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.

"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.

"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.

To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.

At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.

Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.

In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.

They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.

Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.

The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.

Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.

Bengaluru, Jul 5: Karnataka Chief Minister BS Yediyurappa has asked officials to ensure that all necessary arrangements for COVID-19 patients must be carried out efficiently and transparently, Medical Education Minister Dr K Sudhakar said.

"Karnataka is in a better position due to the efforts and hard work of ministers, doctors, officials and all staff. The cases have increased in Bengaluru and some other districts in last few days due to various reasons. We all have to work hard and contain the spread of virus," Dr Sudhakar told media on Saturday.

"Responsibilities related to policy formulation, preparation of guidelines, communication to media and management of war room have been assigned to me. Deputy Chief Minister Ashwath Narayan has been given the responsibility of managing COVID-19 care centres and Revenue Minister R Ashoka and Chief Minister's political secretary Vishvanath have been given the responsibility of managing private hospitals. The Chief Minister has instructed all of us to work in synergy," he said.

Dr Sudhakar said the matter of imposing lockdown in the state again was discussed in the task force meeting. "I and Deputy Chief Minister suggested that lockdown is not necessary at this stage. The Chief Minister will take a decision on this matter," he added.

Home Minister Basavar Bommai, Health Minister B Sriramulu, Revenue Minister R Ashoka and senior officials were present in the task force meeting.

Mangaluru, May 6: Amidst delay in repatriation of Kannadigas stuck in Gulf countries including UAE and Saudi Arabia, on behalf of the office bearers, the executive committee and members of the Bearys Chamber of Commerce & Industry, its president Mr S M Rasheed Haji and executive committee member U T Ifthikar Ali today (May 6) called on authorities concerned in Dakshina Kannada to persuade them to follow up with the State and Central level authorities.  

The duo met Nalin Kumar Kateel, Dakshina Kannada MP, who immediately contacted Pralhad Joshi, Minister of Parliamentary Affairs, over phone and urged him to take up the issue with the external affairs ministry. Mr Joshi told Mr Kateel that efforts are still underway to bring back Kannadigas stranded in Gulf countries. However flights schedules are yet to be finalised.

The duo then met Kota Srinivas Poojary, district in-charge minister, who said that the government is prepared to handle the repatriation flights and passengers. 

The duo also met IAS officer Rahul Shinde, who is in-charge of affairs related to international passengers coming to Dakshina Kannada amid covid-19 crisis. Meanwhile, Zakariya Jokatte, president of Jubail unit of BCCI, spoke to Mr Shindhe over phone.

The official explained that the govt has made elaborate arrangements to conduct medical test of passengers on arrival at the Mangaluru International Airport. 

The passengers will be categorised into A, B and C groups depending on their symptoms and co-morbid conditions. The category A passengers (symptomatic passengers) will be sent to isolation hospitals which may be Covid care centres. Category B passengers (asymptomatic but suffering from co-morbid conditions) will be quarantined at hotels, hostels, guest houses etc. Category C passengers (asymptomatic and healthy) will be home quarantined.

The minister and official also sought BCCI’s cooperation in handling the situation. 

Quarantine accommodation facility 

Yenepoya group has already offered two of their hotels as quarantine accommodation and promised to offer one more.  Entrepreneur U Kanachur Monu and many others too have offered their hotels as quarantine accommodation in Mangaluru. 

District administration has asked Treebo, a hotel aggregator to list such willing facilities on their website.