Rs 28,000-cr power scam: Ready for narco test, says Shobha

Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.

However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.

New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.

The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.

It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.

"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.

As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.

"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.

"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.

To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.

At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.

Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.

In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.

They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.

Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.

The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.

Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.

Bengaluru, Apr 8: Heavy rain lashed Belthangady taluk in Dakshina Kannada district and parts of Udupi district on Tuesday providing much-needed relief to the people from the sultry heat.

Belthangady, Guruvayanakere, Madantyaru, Venoor, Naravi and surrounding areas received rain coupled with lightning and thunder. 

Rain also lashed Karkala, Kundapura, Kollur, Siddapura, Gangolli, Hemmady, Uppunda, Shiroor, Hebri and surrounding areas in Udupi district.

Parts of Malnad --- Koppa, Balehonnur and NR Pura taluks in the neighbouring Chikkamagaluru district --- received good rainfall coupled with lightning and thunder.

The rain has brought a smile on the face of coffee growers as it will help in the blossoming of the flowers in coffee plants.

In Kodagu district, heavy rain lashed Madikeri, Hudikeri, Ponnampet, Srimangala, Siddapura, Galiubeedu, Bapoklu, Talacauvery and Bhagamandala.

Parts of Mysuru city and district, Chamarajanagar, and Hassan received a good spell of rain on Monday night, bringing down the mercury levels.

Heavy rain lashed T Narasipur taluk in Mysuru district and the Kothegala Gram panchayat limits received 7 cm rainfall. Karya village in Nanjangud taluk received 5 cm rainfall.

Male Mahadeshwara Hills in Chamarajanagar district received good rain in the evening. 

Meanwhile, the Agriculture Research Station at Naganahalli has predicted thunderstorms, on April 7 and 8 in the region. The research centre recorded 12 mm rain on Sunday night and 22.5 mm on Monday midnight. 

Moderate to heavy rain, accompanied by strong wind and lightning, lashed some parts of Shivamogga district, including Ripponpet, Sorab, Bhadravathi, Thirthahalli, Sagar
and Shikariput. 

Bhatkal in Uttara Kannada district received heavy rain from 4 to 7 pm. The town had also received the rain for about half-an-hour in the morning.

Hosapete town and the surrounding villages also received the rain. At some places, the rain brought down the branches of the trees. The rain has cooled the mercury level at Hosur, Nagenahalli, Basavadurga, Kamalapur, Hampi and other villages in Hosapete taluk. 

Rain also lashed several places in Ballari district, including the Ballari city. Rain, accompanied by hailstones, brought cheers to the people at Kottur. 

Meanwhile, rain and hailstones have destroyed the standing paddy crop in hundreds of acres of land at Maraladinni, Katagal, Uskihal, Belladamaradi and other villages in Maski taluk of Raichur. The farmers are waiting to harvest the crop.

Bengaluru, Apr 30: Chief Minister B S Yediyurappa, has directed the Bengaluru City Police to return all the vehicles, which were seized during the Coronavirus Lockdown period, for having flouted rules.

The City Police Commissioner, Bhaskar Rao, informed that it was decided to return the seized vehicles to the owners, after verifying documents.

He said that the vehicles had been seized while enforcing strict guidelines, issued to prevent the spread of the COVID-19 virus, in the city.