Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.
However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.
New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.
The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.
It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.
"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.
As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.
"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.
"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.
To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.
At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.
Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.
In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.
They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.
Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.
The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.
Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.
Comments
RSS is the only enemy of India.
RSS should be allowed to wear pants. They look like mentally backward people.
Muslims will manage to get back RSS weapons.
Interesting to hear the jokes of kothi Ann...
Sanghi goon out of India.....staying in Buddha land and disrupting the unity of Indians.....soon should be behind bars....jai hind....
@Naren
Don't think that staying in singapore. And giving communal lines. Will get away from this. Ur each and every comment might be monitoring.
Once police catch u, then ur life will be behind the bars.
Think before u com
@Naren
Don't think that staying in singapore. And giving communal lines. Will get away from this. Ur each and every comment might be monitoring.
Once police catch u, then ur life will be behind the bars.
Think before u com
@Naren
WHY ??? THEY DONT HAVE GUN OF THEIR OWN. I THINK EVEN NAREN TOO WANTS THE GUN. HE ALSO DONT HAVE. POOR CHEDDY?
Donkey never disobedient to its master... whatever loaded on it, it will take...
Similarly there are few human beings despite lot of evidence of the cheddis involvement in deception... They never want to accept the REALITY of their deception and want to continue like the donkeys take their load.. with their mind filled with lies.
We say wake up guys.. look outside the cheddi installed software in your mind and use your God given intellect.
An intelligent human being will understand when shown with proof... and many times cheddis were caught of their dirty activities of doing their evil acts and blaming others...
Karkera exposed their evil acts...
Writers too exposed them
Bomb blast in their own cell
Saffron IT cell exposed with their fake display of nationalism
JNU video tampered
cheddi wearing burka caught red handed last week...
Cow business exposed too
Pakistan flag hositing too caught red handed
Fake FB account too caught red handed...
Only God knows how much bombs they keep in their own temples to create unrest in the society...
Naren, you must be Godse's elder brother....calm down guy....we all know what is RSS all about.....
No wonder. Over and again they openly admitted that they are the manufaturers of terror factories.
Jihadis are having honey moon period as it is khan grace govt as this govt licks their feet ....but everyday is not Sunday ....if jihadis are so powerful...they must directly fight ...not from behind ....if jihadis were so powerful they would have ruled whole world thru oic ...but looking at their mujra infront of Israel only we can make out hahaha....if sangh decides jihadist forces shud run for cover like how they ran in gujarath and muzzaffar Nagar ...we are showing maximum restraint becoz we honour our constitution and respect rule of land....bholo Bharath mata ki jai ..jai sangh parivar ....
We already carry it inside our jockeys......what about chaddeez...if they don't have then why they are wearing it..
.
@Brother Venki Cracked a good Joke.Joke of the Millennium.
Do we have another sample like VENKI in India.Please let us know.We need to send to the Kargil area to entertain our Soldiers.So that they can relax their mind by listening such Jokes.
G
What a funny guys they have with them. Mangana Kaiyalli Manikya...
Give them rights to allow Weapons as well allow them to Shoot who ever they wants.
Aur kya kya chayiye? Ek lambi list karo aur khadey hojao line mey.. Dharpok insaan.. LOL .
Some are getting Y guards, some are for Z guards.. Some need x guards.. Until when you chaddis will keep begging??
Hahaha. Saale Darrpok. No doubt they are criminals. Because they are always afraid of death. Noorukala iliyagi baalokkinta mooru kaala huliyagi baalode melu.
Someone was barking before that 60% of the police are from RRSS....
Where are they NOW ... why dont they Protect Your own men even after we citizens pay from our tax money for their jobs.... U cheddis are useless in taking responsibility to protect the society and now they dont even able to protect their own members..
Are the 60% turned their hearts and became good and thought of helping people rather than continuing supporting the cheddi evils... if it is, then it will be good for the people and the society...
Dear,
Please now itself list out your other demands, we will support for police commissioner permission.
Hope your request is to only for your so called brahmin community ?
Disaster, dont forget that they killed father of nation, Mahatma Gandhi, cant trust them at all....
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