Saudi Crown Prince labels Iran’s Khamenei 'new Hitler'

Beijing/Zurich, Mar 4: China has approved the use of Swiss drugmaker Roche's anti-inflammation drug Actemra for patients who develop severe complications from the coronavirus as it urgently hunts for new ways to combat the deadly infection that is spreading worldwide.

China is hoping that some older drugs could stop severe cytokine release syndrome (CRS), or cytokine storms, an overreaction of the immune system which is considered a major factor behind catastrophic organ failure and death in some coronavirus patients.

Actemra, a biologic drug approved in 2010 in the United States for rheumatoid arthritis (RA), inhibits high Interleukin 6 (IL-6) protein levels that drive some inflammatory diseases.

China's National Health Commission said in treatment guidelines published online on Wednesday that Actemra can now be used to treat coronavirus patients with serious lung damage and high IL-6 levels.

Separately, researchers in the country are testing Actemra, known generically as tocilizumab, in a clinical trial expected to include 188 coronavirus patients and running until May 10.

Roche, which donated 14 million yuan ($2.02 million) worth of Actemra during February, said the trial was initiated independently by a third party with the aim of exploring the efficacy and safety of the drug in coronavirus patients with CRS.

It added that there was currently no published clinical trial data on the drug's safety or efficacy against the virus.

More than 3,000 people have died and 93,000 have been infected by the novel coronavirus thought to have originated in Wuhan, China, before spreading to around 90 countries including the United States, Italy, Switzerland, France and Germany.

The Swiss company, for which China is its No. 2 market behind the United States, also makes diagnostic gear to detect the coronavirus.

Since Actemra's approval a decade ago, it has become a go-to drug against other inflammatory conditions, including cytokine storms in cancer patients receiving cell therapies from Novartis and Gilead Sciences.

In 2012 it helped save the life of a young U.S. girl, the first child to be treated for leukaemia with Novatis' Kymriah, from a post-treatment rush of IL-6.

Priced at between $20-30,000 annually for RA according to SSR Health, Roche's medicine is also used for rare juvenile arthritis and giant cell arteritis, or inflammation of the blood vessels.

Davos, Jan 20: India's richest 1 per cent hold more than four-times the wealth held by 953 million people who make up for the bottom 70 per cent of the country's population, while the total wealth of all Indian billionaires is more than the full-year budget, a new study said on Monday.

Releasing the study 'Time to Care' here ahead of the 50th annual meeting of the World Economic Forum (WEF), rights group Oxfam also said the world's 2,153 billionaires have more wealth than the 4.6 billion people who make up 60 per cent of the planet's population.

The report flagged that global inequality is shockingly entrenched and vast and the number of billionaires has doubled in the last decade, despite their combined wealth having declined in the last year.

"The gap between rich and poor can't be resolved without deliberate inequality-busting policies, and too few governments are committed to these," said Oxfam India CEO Amitabh Behar, who is here to represent the Oxfam confederation this year.

The issues of income and gender inequality are expected to figure prominently in discussions at the five-day summit of the WEF, starting Monday. The WEF's annual global risks Report has also warned that the downward pressure on the global economy from macroeconomic fragilities and financial inequality continued to intensify in 2019.

Concern about inequality underlies recent social unrest in almost every continent, although it may be sparked by different tipping points such as corruption, constitutional breaches, or the rise in prices for basic goods and services, as per the WEF report.

Although global inequality has declined over the past three decades, domestic income inequality has risen in many countries, particularly in advanced economies and reached historic highs in some, the Global Risks Report flagged last week.

The Oxfam report further said "sexist" economies are fuelling the inequality crisis by enabling a wealthy elite to accumulate vast fortunes at the expense of ordinary people and particularly poor women and girls.

Regarding India, Oxfam said the combined total wealth of 63 Indian billionaires is higher than the total Union Budget of India for the fiscal year 2018-19 which was at Rs 24,42,200 crore.

"Our broken economies are lining the pockets of billionaires and big business at the expense of ordinary men and women. No wonder people are starting to question whether billionaires should even exist," Behar said.

As per the report, it would take a female domestic worker 22,277 years to earn what a top CEO of a technology company makes in one year.

With earnings pegged at Rs 106 per second, a tech CEO would make more in 10 minutes than what a domestic worker would make in one year.

It further said women and girls put in 3.26 billion hours of unpaid care work each and every day -- a contribution to the Indian economy of at least Rs 19 lakh crore a year, which is 20 times the entire education budget of India in 2019 (Rs 93,000 crore).

Besides, direct public investments in the care economy of 2 per cent of GDP would potentially create 11 million new jobs and make up for the 11 million jobs lost in 2018, the report said.

Behar said the gap between rich and poor cannot be resolved without deliberate inequality-busting policies, and too few governments are committed to these.

He said women and girls are among those who benefit the least from today's economic system.

"They spend billions of hours cooking, cleaning and caring for children and the elderly. Unpaid care work is the 'hidden engine' that keeps the wheels of our economies, businesses and societies moving.

"It is driven by women who often have little time to get an education, earn a decent living or have a say in how our societies are run, and who are therefore trapped at the bottom of the economy,” Behar added.

Oxfam said governments are massively under-taxing the wealthiest individuals and corporations and failing to collect revenues that could help lift the responsibility of care from women and tackle poverty and inequality.

Besides, the governments are also underfunding vital public services and infrastructure that could help reduce women and girls' workload, the report said.

As per the global survey, the 22 richest men in the world have more wealth than all the women in Africa.

Besides, women and girls put in 12.5 billion hours of unpaid care work each and every day -- a contribution to the global economy of at least USD 10.8 trillion a year, more than three times the size of the global tech industry.

Getting the richest one per cent to pay just 0.5 per cent extra tax on their wealth over the next 10 years would equal the investment needed to create 117 million jobs in sectors such as elderly and childcare, education and health.

Governments must prioritise care as being as important as all other sectors in order to build more human economies that work for everyone, not just a fortunate few, Behar said.

Oxfam said its calculations are based on the latest data sources available, including from the Credit Suisse Research Institute's Global Wealth Databook 2019 and Forbes' 2019 billionaires list.

Feb 5: US President Donald Trump delivered his third State of the Union address on Tuesday, the eve of his expected impeachment acquittal in the United States Senate.

The mood in the House of Representatives reflected the divisions running across the country. Republicans cheered as Trump was introduced, with some chanting "four more years" while Democrats stood silently.

On the foreign policy front, Trump said the US is "working to end America's wars in the Middle East".

He boasted about his decision to order the killing of top Iranian Commander Qassem Soliemani. That decision escalated tensions between the US and Iran, with many fearing an outright war.

Iran retaliated by attacking two Iraqi military bases housing US troops. After Trump initially said no troops were injured, the Defense Department announced dozens of US soldiers had been diagnosed with traumatic brain injuries.

Trump also reiterated his vow to withdraw US troops from Afghanistan. When he plans to do that, however, remains unclear.

US special envoy Zalmay Khalilzad told Afghan President Ashraf Ghani earlier this week that there has not been any significant progress in his talks with the Taliban. Khalilzad said he was hopeful of reaching an understanding with the group on reduction of hostilities, but did not offer any timeframe.

Trump also touted his newly-unveiled Middle East plan, which has been vehemently rejected by Palestinians.

And he received loud applause after reminding the country that ISIL (ISIS) leader Abu Bakr al-Baghdadi was killed last year in a US military operation in Syria.

"Today, the ISIS territorial caliphate has been 100 percent destroyed, and the founder and leader of ISIS - the bloodthirsty killer Al Baghdadi - is dead!" Trump said.

Economy

Trump spent much of his speech highlighting the economy's strength, including low unemployment, stressing how it has helped blue-collar workers and the middle class, though the period of growth began under his predecessor, Barack Obama.

"In just three short years, we have shattered the mentality of American decline and we have rejected the downsizing of America's destiny. We are moving forward at a pace that was unimaginable just a short time ago, and we are never going back!" Trump declared.

And what Trump calls an unprecedented boom is, by many measures, not all that different from the solid economy he inherited from Obama. Economic growth was 2.3 percent in 2019, matching the average pace since the Great Recession ended a decade ago in the first year of Obama's eight-year presidency.

Trump stressed the new trade agreements he has negotiated, including his phase-one deal with China and the United States-Mexico-Canada agreement he signed last month.

Throughout his presidency, Trump has frequently touted his stewardship of the US economy. As recently as two weeks ago, he claimed it was in "a rather dismal state" until he and his administration turned it into a "roaring geyser of opportunity".

But the numbers do not support the "geyser" narrative. There are signs the record US economic expansion - now in its 11th year - is getting long in the tooth.

Job creation is slowing. And the US economy's modest 2.3 percent growth was well short of the 3 percent growth Trump had predicted following a $1.5 trillion tax cut package he and his fellow Republicans pushed through Congress in 2017.

Trump's trade war with China weighed on US manufacturing last year as businesses held back on investment. And while factory activity bounced back in January amid the signing of a phase-one trade deal between Washington and Beijing, US tariffs still remain in place on some $360bn of Chinese goods.

The coronavirus outbreak and the ongoing troubles for Boeing surrounding the 737 MAX could also present headwinds to growth, analysts say.

Awkward moment at awkward time

One of the big questions of the night was whether Trump would directly mention impeachment. He chose to stay away. The House impeached the president at the end of last year for abuse of power related to his dealings with Ukraine and obstruction of Congress for refusing to participate in the impeachment inquiry.

The Senate started its trial more than two weeks ago, and a final vote is scheduled for 4pm local time (21GMT) on Wednesday.

Trump shared an awkward moment with House Speaker Nancy Pelosi, who kicked off the House's impeachment inquiry in September following a whistle-blower complaint that centred on Trump's efforts to get Ukraine to launch investigations into the president's political rival.

At the start of Trump's speech on Tuesday night, it appeared Pelosi went to shake the president's hand, a gesture amid the impeachment proceedings.

The president was presenting folios to Pelosi and Vice President Mike Pence as he arrived for the evening speech when it appears she reached for the shake. At the same time, Trump turned away from her to face the audience of lawmakers gathered for the annual address.

Pelosi gave a look.

Later on Twitter, Pelosi tweeted that "Democrats will never stop extending the hand of friendship to get the job done #ForThePeople. We will work to find common ground where we can, but will stand our ground where we cannot".

After the address was over, Pelosi ripped up her copy of the speech - a move the White House criticised.

Trump is only the third president to be impeached. He has denied any wrongdoing.

While some Republicans have acknowledged Trump did something wrong, they've argued that it didn't amount to an impeachable offence. Trump is headed towards an all but certain acquittal on Wednesday in the Republican-led Senate.

Trump appeals to base

As expected, Trump also dedicated a section to "American values", discussing efforts to protect "religious liberties" and limit access to abortion as he continues to court the evangelical and conservative Christian voters who form a crucial part of his base.

He attacked the Democrats over their healthcare plans, labelling them "socialist".

He brought up his signature campaign issue - immigration, at times making untrue or misleading statements.

"Before I came into office, if you showed up illegally on our southern border and were arrested, you were simply released and allowed into our country, never to be seen again," Trump falsely. "My administration has ended catch-and-release. If you come illegally, you will now be promptly removed."

But under previous administrations, Mexicans were quickly returned back over the US-Mexico border, while others were held in detention until they were deported. Some migrants from other countries were released into the interior of the US to wait out their immigration cases.

And despite Trump's claims that all irregular migrants are now "promptly" removed, there is a one million immigration court case backlog, which means many migrants wait up to three years before a court hearing before a judge who will determine whether someone is deported. After a judge rules a migrant deported, travel papers must be obtained, which often leads to further delays.

As for ending the so-called "catch and release" policy, Trump actually expanded that policy last year during a surge in migrants, releasing thousands of migrants who flooded shelters along the border. The surge has since passed, so fewer people are being held and fewer would need to be released. But an effort by immigration officials to detain children indefinitely was blocked by a judge, so children are still released into the country.

In a gesture that left nearly everyone - including its recipient - looking dumbfounded, Trump announced he was giving right-wing radio host Rush Limbaugh the nation's highest civilian honour.

Limbaugh, who announced this week that he had advanced lung cancer, appeared stunned, his jaw visibly dropping as Trump made the announcement. Others sat in silence as first lady Melania Trump draped the medal around his neck on the spot.

"Thank you for your decades of tireless devotion to our country," Trump told Limbaugh, who often promotes conspiracy theories on his radio show.

Boycott, walkouts

At least 10 Democratic lawmakers, including some who have been attacked by the president, boycotted the address in a sign of protests.

"After much deliberation, I have decided that I will not use my presence at a state ceremony to normalise Trump's lawless conduct & subversion of the Constitution," Representative Alexandria Ocasio-Cortez said in a series of tweets announcing her decision.

Ocasio-Cortez, as well as Representative Ayanna Pressley, who also boycotted, were the subjects of racist attacks by the president last year that resulted in the House voting to condemned his comments, telling the pair and two other congresswoman of colour - Ilhan Omar and Rashida Tlaib - to "go back" to their countries. All four are US citizens.

Omar and Rashida Tlaib, the first two Muslim women in Congress, attended the address, wearing traditional Palestinian and Somali clothing.

"This is what America looks like," Omar tweeted.

Tlaib, along with some other Democratic representatives said they walked out of Trump's speech, calling it "shameless".

Dozens of other congresswomen wore white, representing the colour of women suffragettes.

Other Democrats wore red, white and blue-striped lapel pins to highlight climate change, saying Trump has rolled back environmental safeguards and given free rein to polluters.

Michigan Democratic Governor Gretchen Whitmer delivered her party's official response and drew a contrast between actions taken by Democrats and the president's rhetoric.

"It doesn't matter what the president says about the stock market," Whitmer said. "What matters is that millions of people struggle to get by or don't have enough money at the end of the month after paying for transportation, student loans, or prescription drugs."