May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.
According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.
"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.
They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.
Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.
"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.
"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.
In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.
"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.
The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.
These children were then confirmed to have COVID-19.
While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.
Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.
According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.
"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.
Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.
While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.
However, he cautioned that more research is needed to confirm their findings.
"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.
Comments
Jihadi MLAs of Mangalore are hell bent on supporting these muslim extremists. No action taken on people vandalising the property of innocents. What these fools are doing in the hospital?
Come on guys grow up, Let the people of city live with peace and love.
If some one is attacked, then don't take any revenge.
Let the police handle it. Why are you guys taking law on your side and breaking public properties.
why security now, whatever they wanted to they just did it.
Bajrangies dont have any work to do....why dont they take some brooms and clean the city so that they get good wishes from people as well God....by creating problems, they aren't gonna achieve anything in the world at all....
bajarangdal people are simply making nonsense and not letting us to leave peaceful life. please ban all the sangha parivars
kachadi saieeri
Until unless there is a strict law and no bail , this will not stop.
Please do not disturb peace lovers, punish whoever it is and do not give bail, no community supports this type of disturbances, please do not name any religion, just join to punish whoever the trouble makers.
And fight for the law and order to the long term imprisonment.
look at them they are sleeping simply in the hospital. simply making conspiracy.. all flowing because of congress support.
1week continues bundh needed :)
congress ruled mangalore, this s common to hear.
look at the property they damaged, they are shockingly watching.
shoot the bloody goons whoever damages public property.
some group of people want thr stick to handle, for that everyone should bare the loss of this bloody goons.
Faisalnagar, ullal ruled by PFI. beware
why simply damaging the public property, seriously what are they getting after doing like this.
this bajarangdal people will not allow normal people to leave happily everytime making noise in the society.
seriously how dare are they to damage public property
please not again.
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