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San Diego, Apr 15: Several people lost their sense of smell or taste weeks ago globally and are still waiting for it to come back and now, researchers have identified an association between sensory loss and novel coronavirus 2019 (COVID-19) infection, indicating that loss of smell and taste may be considered as early symptoms of the deadly disease.

Interestingly, the study also found that persons who reported experiencing a sore throat more often tested negative for COVID-19.

The team from University of California-San Diego found high prevalence and unique presentation of certain sensory impairments in patients positive with COVID-19.

Of those who reported a loss of smell and taste, the loss was typically profound, not mild.

"Based on our study, if you have smell and taste loss, you are more than 10 times more likely to have COVID-19 infection than other causes of infection. The most common first sign of a COVID-19 infection remains fever, but fatigue and loss of smell and taste follow as other very common initial symptoms," explained study researcher Carol Yan from UC San Diego.

"We know COVID-19 is an extremely contagious virus. This study supports the need to be aware of smell and taste loss as early signs of COVID-19," Yan added.

For the findings, published in the journal International Forum of Allergy and Rhinology, the research team surveyed 1,480 patients with flu-like symptoms and concerns regarding potential COVID-19 infection who underwent testing at UC San Diego Health from March 3 through March 29, 2020.

Within that total, 102 patients tested positive for the virus and 1,378 tested negatives. The study included responses from 59 COVID-19-positive patients and 203 COVID-19-negative patients.

Encouragingly, the rate of recovery of smell and taste was high and occurred usually within two to four weeks of infection.

"Our study not only showed that the high incidence of smell and taste is specific to COVID-19 infection but we fortunately also found that for the majority of people sensory recovery was generally rapid," said Yan.

"Among the COVID-19 patients with smell loss, more than 70 per cent had reported improvement of smell at the time of the survey and of those who hadn't reported improvement, many had only been diagnosed recently," she added.

Sensory return typically matched the timing of disease recovery.

In an effort to decrease the risk of virus transmission, UC San Diego Health now includes loss of smell and taste as a screening requirement for visitors and staff, as well as a marker for testing patients who may be positive for the virus.

"It is our hope that with these findings other institutions will follow suit and not only list smell and taste loss as a symptom of COVID-19, but use it as a screening measure for the virus across the world," Yan said.

Apr 21: An 80-year-old COVID-19 patient has died in Karnataka's Kalaburagi district, taking the death toll in the state to 17, Medical Education Minister K Sudhakar said on Tuesday.

The elderly person was suffering from Parkinson's disease for the last three years and died at a hospital on Monday, the minister said in a tweet.

"The person had developed fever on Sunday and was admitted to the hospital. The patient passed away yesterday at 9 am. Last night at 9 pm the death report came, which confirmed that the person was COVID-19 positive," Sudhakar tweeted.

The total number of COVID-19 infections in the state has crossed the 400-mark, according to last evening's bulletin by the Karnataka health department.

Bengaluru, Mar 13: Amid coronavirus outbreak, all universities, malls, and clubs will remain closed for a week in Karnataka. Karnataka CM Yediyurappa has said no one should travel unless it's an emergency. "All malls, cinema halls, pubs, wedding ceremonies and other large gatherings in the Karnataka have been banned for another one week," Chief Minister Yediyurappa said. This comes hours after the Uttar Pradesh government had decided that all schools, colleges situated in the state will be closed till 31st March 2020.

Following the decision, the Karnataka government on Friday asked doctors and other health staff to work on public holidays also till the spread of coronavirus is contained. Leaves and all week off of state health ministry workers have also been canceled. The government issued a circular stating that certain emergency measures are being taken to control the spread of coronavirus is some parts of the State.

"To manage things in a result-oriented manner, doctors, office personnel, paramedical staff and other permanent and contract employees in hospitals coming under the Health Department have been instructed to work on all public holidays." the government order read.

The decision comes after 76-year-old man in Karnataka's Kalaburagi died of coronavirus and became India's first COVID-19 victim. 46 people in Kalaburagui have been kept under coronavirus quarantine since then. Out of 46, 31 have been put under the "high risk" category. The high-risk persons were shifted to ESIC hospital. Officials said four family members of the man have displayed flu symptoms and their swab samples have been sent for testing in Bengaluru.

Earlier on Friday, an employee of Google's Bengaluru office tested positive for n-coronavirus, taking the total COVID-19 positive cases in Bengaluru to 5. India's total coronavirus positive count rose to 75. Several other states including capital Delhi, Madhya Pradesh, Odisha, Bihar, and Uttar Pradesh invoked various sections of the epidemic disease act. Meanwhile, the Indian Army has also called off all recruitment drive in wake of coronavirus outbreak.