Sleep Deprivation May Lead to Your Brain 'Eating Itself': New Study

Agencies
May 26, 2017

May 26: Sleep deprivation is a long-term condition where you’ve been suffering from lack of sleep persistently over a period of time. It is not one episode of a late-night party but continues over days where one may not be able to get adequate amount of rest every night.brain

This can lead to many health issues like high-stress levels, decreased metabolism, heart and kidney issues and a lack of general well-being. A new study, conducted by Michele Bellesi of the Marche Polytechnic University in Italy, adds to the list of harmful effects of sleep deprivation claiming that it can actually cause the brain to ‘eat itself’.

The experiments were carried out in a mice model and researchers analysed the brains of mice that had regular sleep, spontaneous wake, sleep deprivation and chronic sleep deprivation. With the help of block-face scanning software, scientists were able to measure the synapses and cell processes in the mouse's frontal cortex. They specifically looked at certain cells called astrocytes cells and found that the sleep-deprived mice showed more activity with these cells.

Researchers found that portions of the synapses were literally eaten up by astrocytes because of sleep loss. They were not able to find out the effects of this but they believe that it may not be a bad thing as it could just be a way of cleaning up old brain debris and therefore, more research is required to understand this phenomenon better. The study was published in the Journal of Neuroscience and hints that astrocytes may start breaking down more of the brain’s debris if you’re sleep deprived.

The study also looked at the effect of sleep deprivation on that microglial cells that account for around 15 per cent of cells found within the brain. It shows that chronic sleep restriction (for the mice it was five days of being kept awake) led to increased signs of microglial activation which may lead to serious brain disorders and thus, make these findings worrisome.

Adults should get at least 7 to 9 hours of sleep every night. Anxiety, low immunity, over emotional state and forgetfulness are some of the most common signs of sleep deprivation that you must watch out for and make sure you god good rest daily.

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Agencies
March 16,2020

New Delhi, Mar 16: A recent survey across 140 districts of the country shows that about 54 per cent of Indians are finding travelling to be unsafe as the deadly coronavirus (COVID-19) pandemic sweeps globally.

The big worry that people have is community transmission, something that researchers from around the world have approximated at 10 per cent of total infections and more common in places like Wuhan in China, South Korea, Iran and Italy.

The months of March to June have historically been high travel season for most Indians, largely due to the summer vacations in schools. "But it seems that Indians do not want to take a chance with this rather scary virus and are either cancelling or postponing their travel plans," concluded the survey by LocalCircles.

The survey gathered more than 22,000 responses from participants in tier one, two and three cities. It said 48 per cent Indians plan to cancel their international business travel for the next four months.

Besides, nearly 38 per cent of respondents said they had to pay cancellation fee to the website, travel agent, airline or railways.

"These are testing times for the entire travel and tourism industry -- airlines, hotels, travel agents as well as small tour and taxi operators. The best solution at this point is to adjust cost structures, stay flexible and work with a collective approach to minimise the period of impact to both citizens and business," said LocalCircles.

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Agencies
June 23,2020

The record levels of new daily COVID-19 cases are due to the fact that the pandemic is peaking in a number of big countries at the same time and reflect a change in the virus' global activity, the World Health Organisation said.

At a media briefing on Monday, WHO's emergencies chief Dr Michael Ryan said that the numbers are increasing because the epidemic is developing in a number of populous countries at the same time.

Some countries have attributed their increased caseload to more testing, including India and the US But Ryan dismissed that explanation.

We do not believe this is a testing phenomenon, he said, noting that numerous countries have also noted marked increases in hospital admissions and deaths neither of which cannot be explained by increased testing.

There definitely is a shift in that the virus is now very well established, Ryan said. The epidemic is now peaking or moving towards a peak in a number of large countries.

He added the situation was definitely accelerating in a number of countries, including the US and others in South Asia, the Middle East and Africa.

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Agencies
July 8,2020

Probiotics that broaden the mix of helpful bacteria in the gut may help to ease depression, say researchers.

Foods that broaden the profile of helpful bacteria in the gut are collectively known as probiotics. These "good bacteria" can be taken as supplements, or found naturally in yoghurts or fermented foods.

For the findings, the research team from the University of Brighton in the UK searched for relevant studies published in English between 2003 and 2019, which looked at the potential therapeutic contribution of pre-and probiotics in adults with depression and/or anxiety disorders.

Out of an initial haul of 71 studies, just seven met all the criteria for inclusion. All 7 investigated at least one probiotic strain; four looked at the effect of combinations of multiple strains.In all, 12 probiotic strains featured in the selected studies, primarily Lactobacillus acidophilus, Lactobacillus casei, and Bifidobacterium bifidium.

One study looked at combined pre-probiotic treatment, while one looked at prebiotic therapy by itself. The studies varied considerably in their design, methods used, and clinical considerations, but all of them concluded that probiotic supplements either alone or in combination with prebiotics may be linked to measurable reductions in depression.

And every study showed a significant fall or improvement in anxiety symptoms and clinically relevant changes in biochemical measures of anxiety or depression with probiotic or combined pre-probiotic use.

Of the 12 different probiotics investigated, 11 were potentially useful, the findings showed.'Probiotics may help reduce the production of inflammatory chemicals, such as cytokines, as is the case in inflammatory bowel disease, the researchers suggested.

"They may help direct the action of tryptophan, a chemical thought to be important in the gut-brain axis in psychiatric disorders," they added.

In this way, with a better understanding of the mechanisms, probiotics may prove to be a useful tool across a wide range of conditions," the authors wrote.

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