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May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.

According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.

"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.

They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.

Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.

"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.

"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.

In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.

"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.

The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.

These children were then confirmed to have COVID-19.

While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.

Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.

According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.

"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.

Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.

While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.

However, he cautioned that more research is needed to confirm their findings.

"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.

Bengaluru, Jul 2: As many as 3,363 students from Covid-19 containment zones have appeared for SSLC examinations in different parts of Karnataka till yesterday. On the first day of exam, i.e., on June 25, only 998 students these zones had written the exam.

In the past few days the number of containment zones has increased across the state in general and Bengaluru in particular. In all, 32 students could not appear for the exam as they turned positive.

While on June 25, the number of students who were found unwell during the check up at exam centre was 201, it was 613 on Wednesday. Students who are sick and those from the containment zones take the exam in a different room.

The social science exam on Wednesday saw an attendance percentage of 97.96 (7.68 lakh). This was against 98.78% last year. There were 7.45 lakh fresh candidates, 20,000 private candidates and 593 from outside the state.

Five students in Yadgir district were given question papers based on the old syllabus for maths exam on June 27. Their answerscripts will be evaluated separately and action will be taken against the officials.

Malpractices assisted by schools by switching off CCTV cameras were reported in Ballari and Koppal. “We’ve completed all the core subjects. Now only languages are left. We’ll complete them too in a safe environment,” said S Suresh Kumar, primary and secondary education minister.

Bengaluru, Apr 15: Karnataka government will explore Ayurveda for fighting the deadly COVID-19, Ayurveda practitioner Dr Giridhar Kaje said here on Wednesday.

After meeting the Chief Minister, Dr Kaje informed media that on a trial basis, ten Coronavirus patients will be administered Ayurvedic treatment in a designated hospital.

Chief Minister B S Yediyurappa has consulted senior doctors on the issue, he said.