Those who killed Gauri, Kalburgi will be arrested shortly, says Home Minister

Bengaluru, Feb 18: A 26-year-old Kannada singer committed suicide over alleged dowry harassment on Monday. Sushmitha, a playback singer who got married to Sharath Kumar about one-and-a-half years ago, hung herself from the ceiling at her parent's home in Nagarabhavi, Bengaluru on Monday.

The singer sent a Whatsapp to her brother and mother before hanging herself early morning on Monday. She accused her husband and his relatives of dowry harassment in her death note.

According to Bengaluru Police, the singer has accused her husband, his sister and his aunt of harassing her for dowry in her death note. On Monday morning, Sushmitha's brother alerted the police after he found her dead body hanging from the ceiling. She used her dupatta to hang herself.

Sushmitha had lent her voice for Kannada songs in films like Haalu Thuppa and Srisamanya.

Police informed that Sushmitha sent a Whatsapp message to her brother, Sachin, at around 1 am on Sunday and explained that her husband Sharath and her relatives have been harassing her since the time she got married. Sachin read the message at around 5:30am and rushed to her room where he found her hanging from the ceiling.

In the text message, Sushmitha wrote that her husband, Sharath, his sister, Geetha, and his aunt, Vydehi, harassed her and they were the reason behind her ending her life. She also stated that she did not want to end her life in their house and hence came to her parents’ house.

The Annapoorneshwari Nagar police have registered a case of dowry death, charging her husband and his sister and aunt based on complaint filed by Sushmitha’s mother Meenakshi. The three accused are on run after hearing about her death and police said that efforts are on to trace them.

Sushmitha's husband Sharath Kumar is a manager in a car showroom and a resident of KS Nagar in Bengaluru.

Bengaluru, Mar 28: Sun Tsu, in 'The Art of War' speaks of a skilful general who can subdue his enemy without any fighting. This constitutes the ultimate triumph which is referred to as stratagem. Today, we would need one such when we are faced with the '21-day corona challenge' for India.
Nearly four weeks back, Dr Jyothsna Rao, Dr Gururaj Rao and I sat across the OPD in the afternoon at HCG Bengaluru discussing our ongoing cancer immunology research. While on this topic, we drifted into the discussion on the coronavirus. During this engaging discussion, we wondered the similarity of the enigma between the virus and cancer. I paused to ask Dr Jyothsna and Dr Guru - how we wish we could do something against this virus.
Dr Jyothsna is a PhD from NCBS and had worked under Dr Ralph Steinman, physician and researcher from Rockefeller University, who won the Nobel Prize for his discovery of the dendritic cell and its role in adaptive immunity in 2011. Dr Gururaj is a molecular and cell biologist who did his PhD at the Chapel Hill, University of North Carolina and is the Director of iCrest.
Jyothsna while hearing our perplexing conversation on the covid intervened, "Yes, surely. I think we should take a break from cancer and focus on the innate and adaptive immunity role in COVID-19."
Thus began this sincere attempt to relook the human immune system from the eyes of the COVID-19.
We have 10 types of immune cells at the least which are widely dispersed in millions across the body. When our body is invaded by a foreign organism (bacteria, fungi or virus), these cells work with each other to destroy the invader.
Now, the question is - how do the immune cells talk to each other? They use small-molecule substances called cytokines (cyto means cells; kine means movement). There are many cytokines that are involved in work on the immune system. The most relevant for viruses are interferons.
Interferons (IFN) as the name reflects have an ability to interfere with the viral activity and stop their multiplication. These specialised signal proteins are released by our cells in response to a viral attack to forewarn other cells. They help build the antiviral proteins within the cells to kill the virus as it tries to invade the new cells.
Historically, interferons are a group of cytokines known to be potent antiviral agents against viruses and a hallmark cytokine induced by the host upon viral infections. Interferons possess unique immunoregulatory activities and are signature cytokines released by (TH1) T immune cells, which are crucial in viral infections.
As the outbreak of COVID-19 grapples us, an urgent need for finding strategies to combat the virus is growing. Coronaviruses (CoVs) are a group of RNA viruses. In patients infected with coronavirus, it was indicated that the activation of the IFN does not occur until 48 hours post-infection. Thus the delayed IFN-related antiviral response by the healthy cells leads to coronavirus evade the immune response.
Numerous studies have presented the success in defeating CoVs by the direct administration of IFNs. In a combination as a concoction, it was shown to synergistically inhibit the virus replication in vitro.
Moreover, it is understood that the earlier induction of IFNs in children although they have a less developed immune system could be the reason behind the children being least affected.
The key to success in reducing the disease fatality might be the stimulation of the immune responses to trigger IFN production at the very early stages of the disease, which might be done through the administration of IFN. Despite the evidence for the efficacy of IFNs in treating CoV-induced infections, the proper dosing and ideal timing for such interventions needs to be verified in clinical trials.
For the later stages of the diseases in advance stages where patients are on ventilator and have developed respiratory distress, we propose to utilise the mesenchymal cells derived from donor bone marrow that have been known to treat acute respiratory syndrome. Mesenchymal cells are known to possess anti-inflammatory activity and thus used often in autoimmune diseases.
With this scientific background, we have activated T cells from healthy donors, in a cGMP facility at iCrest - HCG hospital with an enriched cocktail of cytokines rich in Interferons. Injections of this cocktail we believe will result in a surge of cytokines in the body of the infected person and will boost his ability to fight the virus in the early phases. We are in the initial phases of this study and hope to be ready in the coming weeks with meaningful data on its potential utility.
Currently, it awaits government approvals (Union and state) and we have applied to central drugs authority for their initial evaluation and further directions.
As my Guru often expounded the philosophy of 'Seva' - the goal of education is knowledge, the end goal of knowledge is service. In this attempt to serve our fellow humans at this brink of unprecedented crisis, medical fraternity stands with you and promises to do our best for your safety.
We assure to exhaust every bit of our spirit in this fight against coronavirus. We have lost the sight of shores and travelled thus far, but that is the mandatory first step to cross the ocean. Are we going to succeed in this battle, is something only time will answer. 

Mangaluru, Mar 7: Deputy Chief Minister Dr. Ashwatha Narayana said journalists are facing a challenging task of functioning with credibility while also upholding their professional ethics in this age of globalization where monetary aspects have gained great significance.

Inaugurating the 35th state-level Journalists’ Conference at the Kudmul Rangarao Town Hall on Saturday which was hosted by the DK District Working Journalists’ Union the Deputy CM also said that journalists should refrain from giving priority to political news as that does not serve any purpose for the common man.

Dharmadhikari of the Dharmasthala Temple Dr. D Veerendra Heggade was the chief guest at the event. The souvenir brought out to commemorate the occasion was released by Taranga Editor Sandhya Pai. The Deputy CM also inaugurated a cartoon exhibition organized on the occasion.