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May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.

According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.

"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.

They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.

Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.

"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.

"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.

In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.

"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.

The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.

These children were then confirmed to have COVID-19.

While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.

Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.

According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.

"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.

Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.

While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.

However, he cautioned that more research is needed to confirm their findings.

"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.

Bengaluru, Jan 6: Students and teachers from various colleges in Bengaluru gathered at the Town Hall in the city to protest against the violence which broke out at the Jawaharlal Nehru University (JNU) campus in New Delhi on January 5.

The students raised slogans against Home Minister Amit Shah and Delhi Police.

Placards that read 'The more you attack, the stronger we become', 'Take off your masks terrorist', 'With JNU' were seen during the protest.

"We are here to protest against the incident that took place at JNU with our brothers and sisters. What Delhi Police did was shameful and they should have taken charge of the situation long before and not waited for three hours. We stand with JNU," Nisha, a protestor told ANI.

Professors present at the protest expressed regret over the incident and said attacks on the universities is a sick situation in the country.

"This is sick, where have we come to -- violence in the universities? I was so safe when I was studying in college; what we are giving to our students is horrible," said Sangeeta, a professor present at the protest.

Politicians, cutting across party lines, have condemned the attack on students in JNU and demanded strict action against those found guilty.

More than 18 students were taken to the AIIMS Trauma Centre after a masked mob entered the JNU campus and attacked them and some professors with sticks and rods.

Ahmedabad/New Delhi, Jan 22: Interpol has issued a Blue Corner Notice seeking information about controversial self-styled godman Nithyananda, who fled the country amid allegations of wrongful confinement of children, officials said on Wednesday.

A Blue Corner Notice is issued by the international police cooperation body to collect additional information from its member countries about a person's identity, location or activities in relation to a crime.

The Gujarat Police had sent a request to the CBI, the nodal body for Interpol matters in India, seeking a Blue Corner Notice against Nithyananda, the officials said.

"Interpol issued the Blue Corner Notice against the controversial godman this month," Deputy Superintendent of Police, Ahmedabad (rural), K T Kamariya, told PTI.

The police said they are now working to get Interpol to issue a Red Corner Notice, a global arrest warrant, against Nithyananda.

The Gujarat Police had registered an FIR against Nithyananda after two girls went missing from his ashram in Ahmedabad.

He was charged with kidnapping and wrongful confinement of children to make them collect donations from followers to run his ashram.

Nithyananda was earlier declared wanted by the Gujarat Police.

While police continue to look for him, reports emerged in December last year that he has created a Hindu nation, Kailaasa, with its own flag and political setup, on an island near Ecuador.