Ullal is hub of ganja mafia and communal gangs; govt doing nothing: SDPI

Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.

However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.

New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.

The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.

It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.

"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.

As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.

"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.

"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.

To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.

At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.

Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.

In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.

They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.

Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.

The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.

Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.

Mumbai, Jun 26: In a humanitarian gesture, a mosque in Bhiwandi town of adjoining Thane district has been converted by its administrators into a temporary COVID-19 facility, where oxygen is provided free of cost to patients.

The facility at Makkah Masjid in the Shanti Nagar area of the powerloom town has been set up by the local chapter of Jamaat-e-Islami Hind (JIH), Movement for Peace and Justice and the Shanti Nagar Trust, which runs the mosque.

Apart from putting up five beds equipped with oxygen cylinders, the JIH also delivers them for free to patients homes if required, an office-bearer of the JIH said, adding the makeshift facility is open to all communities.

So far, the Bhiwandi-Nizampur municipality has recorded over 1,332 COVID-19 cases and 88 casualties. It has a mortality rate of 5.26 per cent, a release stated.

"Bhiwandi-Nizampur has been hit hard by the pandemic as it is a congested city. It doesn't even have proper health infrastructure.

"The situation has only worsened during the pandemic as general medical practitioners have shut their clinics fearing the virus spread," said Ausaf Ahmed Falahi, president of the JIH's Bhiwandi chapter.

As a majority of people here lack awareness about the viral disease and are unable to afford treatment, a facility like this one was the need of the hour, he said.

Over 70 persons have benefited from this facility, which has two doctors, while 15 oxygen cylinders have been delivered to the homes of eight COVID-19 patients, Falahi said.

People irrespective of their religion have been availing treatment at the mosque, he added.

"Makkah Masjid has been shut for prayers since the lockdown. So, we decided to use a part of the premises to help those who can't avail treatment elsewhere," said Qaiser Mirza of the Shanti Nagar Trust. 

Mangaluru, Mar 25: The Indian Council of Medical Research (ICMR) has so far given nod to three private laboratories in Karnataka for testing COVID-19. The ICMR comes under the Department of Health, Government of India

The three labs are KMC Hospital Manipal, Shankar Research Centre's laboratory, and SRL laboratory on Bowring Hospital Road at Shivajinagar, Bengaluru.

Eight private labs from Maharashtra, two from Haryana, three from Tamil Nadu, four from Delhi, and three each from Karnataka and Gujarat have been given permission. 

These labs have over 15,000 collection centres all over the country. Blood samples and throat swabs of coronavirus suspects can be given at these centres.