UN demands end to Israeli settlements after US abstains

Washington, May 17: The overall number of global coronavirus cases has increased to over 4.6 million, while the death toll has surpassed 311,000, according to the Johns Hopkins University.

As of Sunday morning, the total number of cases stood at 4,634,068, while the death toll increased to 311,781, the University's Center for Systems Science and Engineering (CSSE) revealed in its latest update.

The US currently accounts for the world's highest number of cases and deaths at 1,467,796 and 88,754, respectively.

In terms of cases, Russia has the second highest number of infections at 272,043, followed by the UK (241,461), Brazil (233,142), Spain (230,698), Italy (224,760), France (179,630), Germany (175,752), Turkey (148,067) and Iran (118,392), the CSSE figures showed.

Meanwhile, the UK accounted for the second highest COVID-19 deaths worldwide at 34,546.

The other countries with over 10,000 deaths are Italy (31,763), Spain (27,563), France (27,532), and Brazil (15,662).

Melbourne, Apr 10: Scientists have identified six drug candidates from more than 10,000 compounds that may help treat COVID-19.

The research, published in the journal Nature, tested the efficacy of approved drugs, drug candidates in clinical trials and other compounds.

"Currently there are no targeted therapeutics or effective treatment options for COVID-19," said Professor Luke Guddat from the University of Queensland in Australia.

"In order to rapidly discover lead compounds for clinical use, we initiated a programme of high-throughput drug screening, both in laboratories and also using the latest computer software to predict how different drugs bind to the virus," Guddat said.

The project targeted the main COVID-19 virus enzyme, known as the main protease or Mpro, which plays a pivotal role in mediating viral replication, the researchers said.

This makes it an attractive drug target for this virus, and as people don't naturally have this enzyme, compounds that target it are likely to have low toxicity, they said.

"We add the drugs directly to the enzyme or to cell cultures growing the virus and assess how much of each compound is required to stop the enzyme from working or to kill the virus. If the amount is small, then we have a promising compound for further studies," said Guddat.

After assaying thousands of drugs, researchers found of the six that appear to be effective in inhibiting the enzyme, one is of particular interest.

"We're particularly looking at several leads that have been subjected to clinical trials including for the prevention and treatment of various disorders such as cardiovascular diseases, arthritis, stroke, atherosclerosis and cancer," Guddat said.

Researchers said compounds that are already along the pipeline to drug discovery are preferred, as they can be further tested as antivirals at an accelerated rate compared to new drug leads that would have to go through this process from scratch.

"With continued and up-scaled efforts we are optimistic that new candidates can enter the COVID-19 drug discovery pipeline in the near future," Guddat said.

New Delhi, May 28: Twitter CEO Jack Dorsey today reinforced his stance on pointing out "incorrect or disputed information about elections globally", a day after US President Donald Trump threatened to shutter social media over Twitter's actions on his posts.

Mr Dorsey appealed to "leave our employees out of this" as the face-off with Mr Trump is likely to escalate.

"Fact check: there is someone ultimately accountable for our actions as a company, and that's me. Please leave our employees out of this. We'll continue to point out incorrect or disputed information about elections globally. And we will admit to and own any mistakes we make," Mr Dorsey tweeted.

"This does not make us an 'arbiter of truth.' Our intention is to connect the dots of conflicting statements and show the information in dispute so people can judge for themselves. More transparency from us is critical so folks can clearly see the why behind our actions," said the Twitter CEO.

Fact check: there is someone ultimately accountable for our actions as a company, and that's me. Please leave our employees out of this. We'll continue to point out incorrect or disputed information about elections globally. And we will admit to and own any mistakes we make.

— jack (@jack) May 28, 2020

"Per our Civic Integrity policy (https://help.twitter.com/en/rules-and-policies/election-integrity-policy), the tweets yesterday may mislead people into thinking they don't need to register to get a ballot (only registered voters receive ballots). We're updating the link on

@realDonaldTrump tweet to make this more clear," Mr Dorsey tweeted.

Twitter had tagged two of Mr Trump's tweets in which he claimed that more mail-in voting would lead to what he called a "rigged election" this November. There is no evidence that attempts are being made to rig the election, and under the tweets Twitter posted a link which read: "Get the facts about mail-in ballots."

Five states in the US already conduct elections primarily by mail-in vote: Utah, Colorado, Hawaii, Washington and Oregon.

For years, Twitter has been accused of ignoring the US President's violation of platform rules with his daily, often hourly barrages of personal insults and inaccurate information sent to more than 80 million followers, news agency AFP reported.

But Twitter's slap on the wrist was enough to drive Mr Trump into a tirade - on Twitter - in which "Republicans feel that Social Media Platforms totally silence conservatives voices. We will strongly regulate, or close them down, before we can ever allow this to happen," Mr Trump said.

He said that an increase in mail-in ballots - seen in some states as vital for allowing people to avoid crowds during the COVID-19 pandemic - will undermine the election.

"It would be a free for all on cheating, forgery and the theft of Ballots," wrote Mr Trump, whose re-election campaign has been knocked off track by the coronavirus crisis. His torrent of angry tweets earned a top-10 trending hashtag: #TrumpMeltdown.

Facebook chief Mark Zuckerberg also waded in to the row, telling Fox News that his social network - still the biggest in the world - has a different policy. "I just believe strongly that Facebook should not be the arbiter of truth of everything that people say online," Mr Zuckerberg said in a snippet of the interview posted online Wednesday by Fox.

"I think, in general, private companies, especially these platform companies, shouldn't be in the position of doing that," he said.

 he claimed that the political right in the US is being censored.

"Republicans feel that Social Media Platforms totally silence conservatives voices. We will strongly regulate, or close them down, before we can ever allow this to happen," Mr Trump said.

He said that an increase in mail-in ballots - seen in some states as vital for allowing people to avoid crowds during the COVID-19 pandemic - will undermine the election.

"It would be a free for all on cheating, forgery and the theft of Ballots," wrote Mr Trump, whose re-election campaign has been knocked off track by the coronavirus crisis. His torrent of angry tweets earned a top-10 trending hashtag: #TrumpMeltdown.

Facebook chief Mark Zuckerberg also waded in to the row, telling Fox News that his social network - still the biggest in the world - has a different policy. "I just believe strongly that Facebook should not be the arbiter of truth of everything that people say online," Mr Zuckerberg said in a snippet of the interview posted online Wednesday by Fox.

"I think, in general, private companies, especially these platform companies, shouldn't be in the position of doing that," he said.