May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.
According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.
"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.
They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.
Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.
"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.
"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.
In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.
"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.
The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.
These children were then confirmed to have COVID-19.
While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.
Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.
According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.
"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.
Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.
While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.
However, he cautioned that more research is needed to confirm their findings.
"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.
The decision was taken by chief minister Siddaramiah, who was looking for a competent and active minister to handle the department of Food and Civil Supplies, after the departure of Dinesh Gundu Rao.
Comments
I am a APL card holder. When we get ration coupons, in coupons for APL 5 kg rice and 5 kg wheat. When we go to ration shop if we say i do not want wheat only 5 kg rice they do not give. They says if you want rice you should take wheat also. Other wise change in your coupon for rice only. But we can not change only rice.
Kindly tell what is the procedure for only rice and no wheat for me.
Sir,
There is shortage of Non subsidised Commercial L.P.Gas cylinder of 19 Kg capacity in the market as HPCL has stopped giving new cylinders to the dealers since past 6 months.
The reason stated is that the turnaround ratio is less than 1 per month.
It is very surprising stand in the open market regime and HPCL has no ground to take such decision in general. The new release is stopped to those dealers who has more than 1 turnaround per month.
Black marketing of commercial cylinders is now a reality.Thanks to HPCL !!!
You are requested to appraise our food minister to manage this issue and oblige.
Regards
Not a good move by CM....Let's see....
Good Move... UTK did better as health minister...
He should also improve the food and civil dept. too... Lets wait before we criticize
this siddu dont have any work to do, Ut khader has done very good job in the field of health all the best for your future work.
One of the biggest blunders of Siddu govt. Outsider Siddu is helping his cheddi dost Ramesh Kumar
New minister in health department has nothing to do. all works are completed my Mr Khader. new one has to just eat, sleep and pose for pics.
congrates. but sad that health dept will be corrupted from today.
congratulation UT Khader, we all NRI's know that u have the capabilty to work in any sector, keep up your good work, lets c what u can do in food and civil supply, being health minister u have given good service as we all know.
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