Veerendra Heggade, Pejawar seer should start projects in North-East: Governor

Mangaluru, Apr 25: The Mangalore Refinery and Petrochemicals Limited (MRPL) has extended vital assistance to hundreds of migrant workers, destitute and needy families during the COVID-19 crisis through its CSR fund.

The lockdown has left thousands of people including migrant workers and destitute in the district, in the lurch. MRPL, using its corporate social responsibility fund through the Dakshina Kannada district administration, has sponsored 50,000 kg rice for the benefit of these needy citizens, a company release here said.

MRPL also donated grocery kits comprising boiled rice, dal, rava, sugar and tea to the needy families in the district, it said.

Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.

However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.

New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.

The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.

It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.

"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.

As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.

"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.

"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.

To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.

At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.

Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.

In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.

They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.

Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.

The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.

Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.

Bengaluru, Apr 11: Former prime minister H D Deve Gowda claimed the lockdown decision was taken in 'haste' without forethought because of which farmers and the working class were 'suffering' and suggested measures to mitigate the impact. The state government should have consulted experienced citizens, officials, progressive farmers, farmer organisations and wholesale traders about the pros and cons before lockdown, he said in a letter to Chief Minister B S Yediyurappa, while highlighting that 61 per cent of the state's population depended on agriculture.

Because of the "hasty decision taken without any preparations", farmers of the country and the state are facing financial distress," he said in the April 9 letter, a copy of which was released to media here on Friday. The JD(S) patriarch suggested taking up some measures, including ensuring no restrictions on agriculture activities, procurement of horticulture produce at a fair price, relaxing export curbs on it, to provide relief to farmers, agriculture labourers, and daily wage workers.

On Sunday, Gowda had said he has assured Prime Minister Narendra Modi of his support in the nation's battle against COVID-19 pandemic when the latter called him to discuss the situation. In his letter to the chief minister, Gowda said: "...the lockdown implemented to control the spread of coronavirus has led our farmers into despair and put their lives into a burning fire.

This lockdown looks like a decision taken at haste without proper thinking and forethought for our farmers, agriculture labourers, and daily wage workers." He said the lockdown decision was taken after remaining 'quite' for about two months since the first corona infection was reported in the country on January 30. Among the suggestions made by the former prime minister include, procurement of horticulture produce at a fair price like in the case of milk from villages by the government through related organisations like Karnataka Horticulture Federation, HOPCOMS among others.

As horticulture produce was perishable, there should be no restriction on its procurement, transportation and marketing; all processing related activities of horticulture produce should be given relaxation from the lockdown, he said. Gowda also called for relaxation on exports for horticulture produce and its processed items. There should be no restriction on agriculture activities; a national grid has to be set up for marketing of horticulture produce, he said.

If such measures were not taken up immediately, the government will have to pay compensation to farmers for losses. Lack of remedial measures would lead to a shortage of supply, leading to rebellion from the people and may result in farmers' suicides and bringing about a situation that might be more grave than coroanvirus, he said.