May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.
According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.
"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.
They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.
Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.
"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.
"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.
In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.
"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.
The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.
These children were then confirmed to have COVID-19.
While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.
Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.
According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.
"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.
Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.
While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.
However, he cautioned that more research is needed to confirm their findings.
"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.
Comments
Tipu is one of the few freedom fighter who didnt bow his head to British and fought bravely and died in the battlefield. unlike RSS, VHP who bowed their head to be their slave. Now these little puppies have grown up to speak against Tiger of Mysore forgetting his contribution to the indian freedom struggle. Secondly if Tipu had converted hindus into islam by force then there would have been not a single Hindu left in the country now while Hindus make up 80% of Indian population. Foolish people talk without any logic.
Hindu jaya Gosh (gosh of beef)
who is tippu. he is a crimnal. why shold we celebrate his birthday?
If these goons kill Gandhi the person who gave freedom and did ultimate sacrifice for the nation, then how can we expect these goons will talk fairly.
Now Mr. Jain himself is a Jain and not Hindu. He should set an example by denouncing his religion and should join Hinduism.
About Muslims joining Hinduism,
Mr. Jain come for a healthy debate.
If Hinduism proved to be true, all Muslims will join Hinduism.
Like wise if Hinduism proved to be untrue, you first join Islam and ask your people to accept Islam.
They only calls... but no body listen to them.
Wah Re Wah... What a meaningful statements by Mr Jain, the member of non violent community! Thooo nin janmakkishtu
Jihadist and Bajrangi's mentality are same. Both are terrorist. Please just ignore them.
instead of this time waste, do good to the country, help poor family to come up in life.
Tiger-Tippu is being remembered for his bravery.... and entire country is appreciating for his hard work....he is the only king stood against british rule at that time....these chaddies were supporting british....nobody from chaddies fought for our country for our freedom....they should be ashamed of themselves.....
Creating violence in the peaceful society is their birth right!!
Bap Ray Bap what's going on here and there, Mallu
We need thorough research to unearth the historical truth.
Tipu was never a freedom fighter and was fighting only to save himself and like mentioned to convert to islam. It cannot be condoned that others did so can he. What kind of logic is this to support tyranny. So by default we are agreeing to BJP's ghar vapsi. What wrong VHP is doing if Tipu was right in his actions.
None of the royalty was \freedom fighter\".They were fighting for their own glory and power. The poor faceless people who died for the country after 1857 were \"freedom fighters\""
none of these castes and religions belongs to India. Hindu, Christian, Muslim. All this people are developing wide spread hatred among people. In India we were having Dravida origin people. They may have converted to Buddism or jainism but not on any compulsions from out side Indians but due to the intuitions from the times GURUS like mahavir or buddha. Even before that we had aadi dravida culture. With out having the detailed study or finding on the back history, we are spreading hatred on starting from edges of the last point.It is mere nonsense. Tipu sulthan the great may have committed crime as a king. the christians preachers may have converted people to their religion by force or else. At this point of time study and analysis may favour some historical revelations but creating hatred in the name of religion and causing poor people to lead violance is a ploy that every religion at every time played in and around the world. Israel, Arab countries, US, UK, Australia and even in Africa these game plan works and the loosers are always the down troden common public and the profit makers are always the top leaders of the religion as well the politicians. This is the corrupt intolerance
Nobody is with clean hands. Something or the other is done by everybody in general for their survival. If everybody's history is revealed the person will be caught in somewhere in the middle of his life. There is no any such great person who did all good things for others. So stop this hatredness and let's see how to move forward with the country where there are types of religion, race, community, caste, creed and culture. If this comment goes on with UCA then they are also poking their nose in the issue which is not related to them. Kindly if you are not able to do goodness please do not agitate the country. The seed sowing job is done by the communal parties in the year 2002 by demolishing Babri Masjid and massacring thousands of people from a particular religion. Remember. Don't blame the religion. and UCA and BJP/ VHP/ BAJRANG DAL or so called sangh parivars is going against the Karnataka government and the INDIAN Government decision. We would like to thank to the HONORABLE CM OF KARNATAKA and the Congress leaders who has taken rigid decision to commemorate Tippu Sulthan. Tippu never opposed. In fact he used to work with secularism where in his court he was giving equal position to all. Like Poornaiah, and the list goes on. He fought with the British rulers bravely. They only awarded him as THE TIGER OF MYSORE for his bravery. Even English mothers tried to make the child sleep by saying his bravery. So stop blaming UCA. This UCA should not come into picture. They also joined. Ha ha ha ha ha !!!!!!!
Thanks to our Historians. These historians were patronized by ruling elite, to give us wrong history. We were fooled. Ms.Danya Rajendran had tweeted that she knows a family by name 70s. That is, they are descendants of 70 families, in Mysore, whose males were killed by this Great Tipu. During his period, there were JUST TWO temples in his kingdom. This fact is also known after this Tipu Jayanthi celebrations by Govt.
Instead we should celebrate GODSE jayanthi,
pathetic people, need to revise History again to these people!!!!
We never want to celebrate anybody's birthday. Only God knows what is Tippu's situation now as every soul shall die and will be asked with what he did with the life that God has given us...
Aren't they all have any intellect?
If Tippu did not started the War with the British, we would still be the slaves of the British and their chamchas , the cheddis.
Why the stupids want us to believe what they say without learning the history...
Cheddi leaders have tricked very easily many ignorants...Wow there are so many, who doenst use their God given intellect... and they stand with the LIARS... for petty gains...
Dont worry God is with those who are truthful... As a whole evils will perish one day
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