May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.
According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.
"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.
They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.
Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.
"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.
"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.
In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.
"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.
The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.
These children were then confirmed to have COVID-19.
While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.
Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.
According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.
"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.
Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.
While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.
However, he cautioned that more research is needed to confirm their findings.
"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.
Comments
Dear Rakesh.
We know how brain is working after cheddi media & teaching have affected U.. and 95% of the cases charged are still not proved and the cheddi authorities are playing with the dumb spectaters like U who support them without your own investigation on the cases which still did not give any proof..... anyway A day will come to judge such cases where innocents have been trapped and the one who gave us this life will judge and on that day no cheddis will come to your rescue for your blind support now. Which U will regret for not using your god given intellectual. Try to know the reality and study on cheddi deception.
Rakesh,
Jamate Islami Hind an institution have no connection with Simi. SIMI is a independent institution which banned now. Its a student movement like ABVP. Jamate Islami Hind have student wing is SIO. I don't know where you got the information that he was with SIMI. Can you furnish the details about the Syed Qasim was with SIMI, failing which you will have apologize in this forum for non authentic information.
SQR Ilyasi we are with you...A goonda coward who is sitting abroad is preaching Hindutva patriotism ..As a Muslim we are not scared of these death threats
this man was with SIMI ... what else we can expect from his son ? Mr Abdullah , clarification , not India , it is muslims only and some left mentally retards . May be he has support from pakistan .
No worry ... India With U. Jai Hind.
Dont worry guys.... for the threats
Allah gives life & death and we muslims believe that.. If you are firm in your belief.. Just pray to him and ask his protection ... Dont worry about the evil .. Unless ALLAH gives permission nothing on the earth will move... even the evil of ravi poojary..
TRUST ALLAH, U are on the safe hand unless ALLAH decreed on U. even if U are harmed. It is the matter is with ALLAH.
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