May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.
According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.
"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.
They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.
Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.
"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.
"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.
In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.
"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.
The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.
These children were then confirmed to have COVID-19.
While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.
Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.
According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.
"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.
Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.
While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.
However, he cautioned that more research is needed to confirm their findings.
"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.
Comments
Dear unknown,
you are the only third grade person in the world who bring religion in all matter,
who is hitler ? kill is uncontable
who is bush ? kill is uncountable
who is modi? killer of gujrath genoicide
people with black suite sitting in parliment and who put bomb on innocient civilin are great & patroit people.
people who fight back are criminal and terror.
we are proud of our islamic religion and not like your assh*le religion who worship million god without address
replace your gobar brain to human brain!! life will enlight
Why these brainless people are killing each other for party.. That killers fate also will be same. But it will be by some other goons
Again political rivalry came into limelight
Shameless creature.. they all doing to defame Islam. True follower of Islam wont do such things
Arrest all goons. Police hesitate to arrest most of the goons because they are working for party as their goon
To where these youths heading.. Shocking
Interesting fact is while classifying terrorists and criminals on the basis of their religion, Most of them are Muslims. I dont know why, but still they will address them as peace lovers and their religion is peaceful one
Inna lillah. I could not understand why Muslim youths are following Shaitaan and making their way to Jahannum. Will they be able to return the life of the youth? Why are they blind? why cant live and let leave other peacefully. No political party will come to your help when you need it. Political party will use you for the benefit only. May Allah bless the deceased with magfirah and bless with right way of thinking to the youths who are running away from right path.
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