May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.
According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.
"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.
They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.
Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.
"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.
"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.
In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.
"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.
The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.
These children were then confirmed to have COVID-19.
While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.
Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.
According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.
"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.
Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.
While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.
However, he cautioned that more research is needed to confirm their findings.
"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.
Comments
Do you know who start the tippu jayanthi dear
This is the fact, a party built on corrupt ideology will not survive. The entire nation will know the truth.
What is their moral value of these guys who killed that person who sacrificed his whole life for the nation. What can we expect from these people. Until the past few years they were agreeing TIPU SULTAN as the best ruler, tiger of Mysore, and the man who taught to resist the invaders.
Just for the personal benefits, the same guys portray him negatively
People of such a mentality should be catalgorized as sick and mentally distorted group who should not be considered fit for election or make any policitical party.
The wise people should boycott such immoral party, Support the fair and the reliable party. If not available go for the least corrupt party.
Eddi is the only CM who spent his life in jail for corruption (not as a freedom fighter)
Think of our future geneations and our children,
God help our country from these corrupt group.
Dear Sandesh
if you want join with bjp policy no objecttion but don't involve Hindu religion. All Hindus are not as you wished.
During BJP govt all these communal leaders including cheddiyurappa was on the dias to celebrated Tipu Jayanthi so now what happen with different colour and tune.
Go with the history i/o rss book.
Jai Hind Jai Karnataka
Why all people blaming BJP. Why this govt cant avoid celebration
BJP leaders are mentally retarded people. Trouble makers
All Hindus should support BJP's decision
BJP openly said they will oppose. If they didnt say anything also they will do the same. They will make trouble as they did previous year
Govt should seek order from hc or sc for arresting all BJP goons
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