Boy or girl? Mother's BP may predict sex of baby

January 13, 2017

Toronto, Jan 13: The sex of a baby may be predicted by the mother's blood pressure, according to a new study which found that women with lower BP before pregnancy are more likely to give birth to a girl.

babyResearchers led by Dr Ravi Retnakaran, endocrinologist at Mount Sinai Hospital in Canada found that while higher blood pressure was an indication that a boy was more likely to be conceived, women with lower blood pressure tended to give birth to a girl.

This "suggests that a woman's blood pressure before pregnancy is a previously unrecognised factor that is associated with her likelihood of delivering a boy or a girl," said Retnakaran.

"This novel insight may hold implications for both reproductive planning and our understanding of the fundamental mechanisms underlying the sex ratio in humans," he said.

The possibility of predicting the sex of the baby in early pregnancy has long been a topic of public fascination, spawning numerous theories of maternal characteristics associated with the presence of a male or female foetus.

These observations raise the possibility that there may be underlying differences that relate to a woman's likelihood of sex-specific fetal loss and hence her likelihood of delivering a boy or girl. However, little is known about such factors in humans.

Researchers established a unique pre-conception cohort consisting of young women who were planning to have a pregnancy in the near future and used the model to evaluate the relationship between maternal pre-pregnancy health and the sex of the baby.

Participants underwent baseline medical assessment at recruitment and then, whenever they subsequently became pregnant, were followed across the pregnancy up to delivery through their clinical care.

Beginning in February 2009, researchers recruited 3375 women in Liuyang, China. Of these, 1,692 women were assessed for blood pressure, cholesterol, triglycerides, and glucose.

After the exclusion of 281 women who were potentially pregnant at their baseline assessment based on back-dating of the length of gestation at delivery, the study population for the analysis consisted of 1,411 women who were assessed at median 26.3 weeks before pregnancy.

Their pregnancies resulted in the delivery of 739 boys and 672 girls.

After adjustment for age, education, smoking, BMI, waist, LDL cholesterol, HDL cholesterol, triglycerides and glucose, mean adjusted systolic blood pressure before pregnancy was found to be higher in women who subsequently had a boy than in those who delivered a girl (106.0 vs 103.3 millimetres of mercury).

Higher maternal blood pressure before pregnancy emerged as an independent predictor of subsequently delivering a boy.

The research was published in the American Journal of Hypertension.

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Agencies
July 21,2020

New Delhi, Jul 21: The Centre has written to all states and union territories warning against the use of N-95 masks with valved respirators by people, saying these do not prevent the virus from spreading out and are "detrimental" to the measures adopted for its containment.

The Director General of Health Services (DGHS) in the Ministry of Health, in a letter to the Principal Secretaries of health and medical education of states, said it has been observed that there is "inappropriate use" of N-95 masks, particularly those with valved respirators, by the public other than designated health workers.

The DGHS referred to the advisory on the use of homemade protective cover for face and mouth available on the website of the Ministry of Health.

"It is to bring to your knowledge that the use of valved respirator N-95 masks is detrimental to the measures adopted for preventing the spread of coronavirus as it does not prevent the virus from escaping out of the mask. In view of the above, I request you to instruct all concerned to follow the use of face/mouth cover and prevent inappropriate use of N-95 masks," DGHS Rajiv Garg said in the letter.

The government had in April issued an advisory on the use of homemade protective cover for face and mouth, asking people to wear it, particularly when they step out of their residences.

The advisory stressed such face covers must be washed and cleaned each day, as instructed, and stated that any used cotton cloth can be used to make this face cover.

The colour of the fabric does not matter but one must ensure that the fabric is washed well in boiling water for five minutes and dried well before making the face cover. Adding salt to this water is recommended, it said.

It also listed the procedures of making such homemade masks, asking to ensure it fits the face well and there are no gaps on the sides.

It urges people to wash hands thoroughly before wearing the face cover, switching to another fresh one as the face cover becomes damp or humid, and never reusing it after single use without cleaning it.

"Never share the face cover with anyone. Every member in a family should have separate face cover," the advisory stated.

India's COVID-19 case tally crossed the 11-lakh mark on Monday, while the total number of recovered patients increased to over seven lakh, according to Union health ministry data.

The death toll due to the disease rose to 27,497 with 681 fatalities reported in one day.

The ministry data updated at 8 am on Monday showed that a record single-day jump of 40,425 COVID-19 cases had taken the total number of cases to 11,18,043.

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Agencies
February 27,2020

Washington D.C, Feb 27: New research shows that adults who have low fruit and vegetable intake are more likely to be diagnosed with an anxiety disorder.

"For those who consumed less than 3 sources of fruits and vegetables daily, there was at least at 24% higher odds of anxiety disorder diagnosis," says the lead author of the Canadian Longitudinal Study, Karen Davison, who is a health science faculty member, nutrition informatics lab director at Kwantlen Polytechnic University, (KPU) and North American Primary Care Research Group Fellow.

"This may also partly explain the findings associated with body composition measures. As levels of total body fat increased beyond 36%, the likelihood of anxiety disorder was increased by more than 70%," states co-author Jose Mora-Almanza, a Mitacs Globalink intern who worked with the study at KPU.

"Increased body fat may be linked to greater inflammation. Emerging research suggests that some anxiety disorders can be linked to inflammation," says Davison.

In addition to diet and body composition measures, the prevalence of anxiety disorders also differed by gender, marital status, income, immigrant status and several health issues.

An important limitation of the study was that the assessment of anxiety disorders was mostly based upon self-reporting of a medical diagnosis.

"It is estimated that 10% of the global population will suffer from anxiety disorders which are a leading cause of disability," says Karen Davison

"Our findings suggest that comprehensive approaches that target health behaviours, including diet, as well as social factors, such as economic status, may help to minimize the burden of anxiety disorders among middle-aged and older adults, including immigrants," she concluded.

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Agencies
April 14,2020

There is no evidence that the Bacille Calmette-Guerin (BCG) vaccine, which is primarily used against tuberculosis, protects people against infection with the novel coronavirus, the World Health Organization (WHO) said.

The WHO therefore didn't recommend BCG vaccination for the prevention of COVID-19 in the absence of evidence, according to its daily situation report on Monday, Xinhua news agency reported.

"There is experimental evidence from both animal and human studies that the BCG vaccine has non-specific effects on the immune system. These effects have not been well characterized and their clinical relevance remains unknown," WHO stated.

Two clinical trials addressing the question are underway, and WHO will evaluate the evidence when it is available, it noted.

BCG vaccination prevents severe forms of tuberculosis in children and diversion of local supplies may result in an increase of disease and deaths from the tuberculosis, it warned.

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