Cat owners may not have mental illness risk: study

February 22, 2017

London, Feb 22: Cat ownership during pregnancy or childhood may not pose a direct risk for psychotic symptoms, according to a new study that casts doubt over suggestions that people who grow up with felines are at higher risk of mental illness.

catsRecent research has suggested that cat ownership might contribute to some mental disorders, because cats are the primary host of the common parasite Toxoplasma Gondii (T Gondii), itself linked to mental health problems such as schizophrenia.

However, the new study by researchers at University College London (UCL) in the UK suggests that cat ownership in pregnancy and childhood does not play a role in developing psychotic symptoms during adolescence.

The study looked at nearly 5,000 people born in 1991 or 1992 who were followed-up until the age of 18. The researchers had data on whether the household had cats while the mother was pregnant and when the children were growing up.

"The message for cat owners is clear: there is no evidence that cats pose a risk to children's mental health," said lead author Francesca Solmi from UCL.

"In our study, initial unadjusted analyses suggested a small link between cat ownership and psychotic symptoms at age 13, but this turned out to be due to other factors.

"Once we controlled for factors such as household over-crowding and socioeconomic status, the data showed that cats were not to blame. Previous studies reporting links between cat ownership and psychosis simply failed to adequately control for other possible explanations," said Solmi.

The new study was significantly more reliable than previous research in this area since the team looked at families who were followed up regularly for almost 20 years.

This is much more reliable than methods used in previous studies, which asked people with and without mental health problems to remember details about their childhood.

Such accounts are more vulnerable to errors in recall which can lead to spurious findings.

Previous studies were also relatively small and had significant gaps in the data, whereas the new study looked at a large population and was able to account for missing data.

The study was not able to measure T Gondii exposure directly, but the results suggest that if the parasite does cause psychiatric problems then cat ownership does not significantly increase exposure.

"Our study suggests that cat ownership during pregnancy or in early childhood does not pose a direct risk for later psychotic symptoms," said senior author James Kirkbride from UCL.

"However, there is good evidence that T Gondii exposure during pregnancy can lead to serious birth defects and other health problems in children. As such, we recommend that pregnant women should continue to follow advice not to handle soiled cat litter in case it contains T Gondii," said Kirkbride.

The study was published in the journal Psychological Medicine.

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Agencies
June 23,2020

The record levels of new daily COVID-19 cases are due to the fact that the pandemic is peaking in a number of big countries at the same time and reflect a change in the virus' global activity, the World Health Organisation said.

At a media briefing on Monday, WHO's emergencies chief Dr Michael Ryan said that the numbers are increasing because the epidemic is developing in a number of populous countries at the same time.

Some countries have attributed their increased caseload to more testing, including India and the US But Ryan dismissed that explanation.

We do not believe this is a testing phenomenon, he said, noting that numerous countries have also noted marked increases in hospital admissions and deaths neither of which cannot be explained by increased testing.

There definitely is a shift in that the virus is now very well established, Ryan said. The epidemic is now peaking or moving towards a peak in a number of large countries.

He added the situation was definitely accelerating in a number of countries, including the US and others in South Asia, the Middle East and Africa.

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Agencies
June 22,2020

A team of scientists has produced first open source all-atom models of full-length COVID-19 Spike protein that facilitates viral entry into host cells – a discovery that can facilitate a faster vaccine and antiviral drug development.

The group from Seoul National University in South Korea, University of Cambridge in the UK and Lehigh University in the US produced the first open-source all-atom models of a full-length S protein.

The researchers say this is of particular importance because the S protein plays a central role in viral entry into cells, making it a main target for vaccine and antiviral drug development.

"Our models are the first full-length SARS-CoV-2 spike (S) protein models that are available to other scientists," said Wonpil Im, a professor in Lehigh University.

"Our team spent days and nights to build these models very carefully from the known cryo-EM structure portions. Modeling was very challenging because there were many regions where simple modeling failed to provide high-quality models," he wrote in a paper published in The Journal of Physical Chemistry B.

Scientists can use the models to conduct innovative and novel simulation research for the prevention and treatment of Covid-19.

Though the coronavirus uses many different proteins to replicate and invade cells, the Spike protein is the major surface protein that it uses to bind to a receptor.

The total number of global COVID-19 cases was nearing 9 million, while the deaths have increased to over 467,000, according to the Johns Hopkins University.

With 2,279,306 cases and 119,967 deaths, the US continues with the world's highest number of COVID-19 infections and fatalities, according to the CSSE.

Brazil comes in the second place with 1,083,341 infections and 50,591 deaths.

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Agencies
July 30,2020

New York, Jul 30: Can the coronavirus spread through the air? Yes, it's possible.

The World Health Organisation recently acknowledged the possibility that Covid-19 might be spread in the air under certain conditions.

Recent Covid-19 outbreaks in crowded indoor settings — restaurants, nightclubs and choir practices — suggest the virus can hang around in the air long enough to potentially infect others if social distancing measures are not strictly enforced.

Experts say the lack of ventilation in these situations is thought to have contributed to spread, and might have allowed the virus to linger in the air longer than normal.

In a report published in May, researchers found that talking produced respiratory droplets that could remain in the air in a closed environment for about eight to 14 minutes.

The WHO says those most at risk from airborne spread are doctors and nurses who perform specialized procedures such as inserting a breathing tube or putting patients on a ventilator.

Medical authorities recommend the use of protective masks and other equipment when doing such procedures.

Scientists maintain it's far less risky to be outside than indoors because virus droplets disperse in the fresh air, reducing the chances of Covid-19 transmission.

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