Children drinking non-cow milk little shorter than peers

Agencies
June 25, 2017

Jun 25: A new study suggests drinking non-cow milk- soy, almond or rice milks - is linked to shorter kids.cowmilk

The study, published in the American Journal of Clinical Nutrition, found that each daily cup of non-cow's milk consumed was associated with 0.4 centimeters (0.15 inches) lower height than average for a child's age.

"We found that children who are consuming non-cow's milk like rice, almond and soy milk tended to be a little bit shorter than children who consumed cow's milk," said Dr. Jonathon Maguire, the study's lead author and a pediatrician and researchers at St. Michael's Hospital in Toronto.

"For example, a 3-year-old child consuming three cups of non-cow's milk relative to cow's milk was on average 1.5 centimeters shorter."

That's over half an inch difference, which Maguire said is "not a tiny difference when you're 3 years old."

The study was a cross-section involving 5,034 healthy Canadian children ranging in age from two to six years old. The subjects were on average 38 months of age, with 51% being male, and were recruited from nine family and pediatric health-care practices from December 2008 to September 2015.

Of those participating, about five percent drank exclusively non-cow's milks, and about 84% drank only cow's milk; about eight percent drank both and about three precent drank neither.

Maguire said the most surprising finding was "that the amount children were shorter depended on how much they were consuming."

"It's not like if you're not consuming cow's milk, you're a little shorter," he said. "It's more like if you are consuming non-cow's milk, with each cup that a child consumes, that child on average appears to be a little bit smaller, a little shorter. That's a bit surprising."

Does it matter if a kid is half an inch shorter at the age of three? Does it correlate to height in adulthood?

"That's one remaining question. We don't know if the kids consuming non-cow's milk, maybe they catch up over time, or maybe they don't. Time's going to have to tell," he said.

"We do know in general as pediatricians that children who are on a certain percentile line in terms of height tend to stay on that line for the rest of their childhood and into adulthood."

The findings are sure to add fire to the ongoing debate about the benefits of cow's milk versus dairy alternatives.

Amy Joy Lanou, a professor of health and wellness at the University of North Carolina-Asheville who was not involved in the research, said she had several issues with the study, most notably why only milk consumption was considered.

"It's just odd to me why we wouldn't be looking at the overall diets of the children," Lanou said. "If they're making the claim that it's because it's the difference in the types of milk the kids are drinking, well, what else are they eating?"

Lanou, whose research has led her to believe that cow's milk is "not a necessary food," said she believes the study makes an improper leap by implying that taller means healthier.

"Taller children and heavier children are not necessarily healthier adults, or even healthier children," she said. "I think they're using height as a marker for health, and I'm not sure that's appropriate."

Connie Weaver, a professor of nutrition science at Purdue University who was also not involved in the study, said she found it interesting.

"This is the first study that I recall directly comparing cow milk with plant-based beverages for a physiological benefit," she wrote in an email. "We know that some of the plant beverages, almond especially, have lower protein contents so I have speculated that calcium absorption may be lower. This would suggest that cow's milk is superior."

However, she says, "A wrong message would be if people who do not consume cow's milk would decide to avoid the plant-based milks also."

The study suggests that one reason for the difference in height might be that plant-based milks do not stimulate insulin-like growth factor, or IGF, production as well as cow's milk does. Studies have found that adults with higher levels of certain IGFs have increased risks of reproductive cancers.

"Having less IGF may compromise height but that may lower risk of fracture -- and some cancers, too," Weaver said.

Overall, she would advise parents that "cow's milk may be the best option, but plant-based beverages provide many needed nutrients like protein, calcium, magnesium, potassium," which is far better than what most kids might prefer to drink.

Lanou would tell parents who are already giving plant-based milks to their children not to worry -- but to make sure their kids are getting enough protein from other sources throughout the day.

Maguire said he'd like to see soy, almond and rice milks more tightly regulated to bring the industry, in line with cow's milk.

"As a consumer and as a parent, you have to be pretty savvy when going to the grocery store to choose a non-cow's milk beverage that has similar nutritional value as cow's milk," he said. "Many of those beverages are marketed as being equivalent to cow's milk when they're not."

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Agencies
May 25,2020

Singapore, May 25: COVID-19 patients are no longer infectious after 11 days of getting sick even though some may still test positive, according to a new study by infectious disease experts in Singapore.

A positive test "does not equate to infectiousness or viable virus," a joint research paper by Singapore's National Centre for Infectious Diseases and the Academy of Medicine, Singapore said. The virus "could not be isolated or cultured after day 11 of illness."

The paper was based on a study of 73 patents in the city-state.

The latest findings may have implications on the country's patient discharge policy. The discharge criteria is currently based on negative test results rather than infectiousness.

Singapore's strategy on managing COVID-19 patients is guided by the latest local and international clinical scientific evidence, and the Ministry of Health will evaluate if the latest evidence can be incorporated into its patient clinical management plan, according to a report by the Straits Times.

So far, 13,882, or about 45% of the total 31,068 Covid-19 patients in Singapore have been discharged from hospitals and community facilities. Singapore reported 642 new Covid-19 cases as of noon on Saturday.

The government has been actively screening pre-school staff as it prepares to reopen pre-schools from June 2. On Friday, two pre-school employees tested positive for the novel coronavirus, bringing the total number of confirmed cases among pre-school staff to seven, according to the Ministry of Health.

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Agencies
January 25,2020

Washington D.C., Jan 25: A new study conducted by a team of researchers reveals why individuals who have a history of early life adversity (ELA) are disproportionately prone to opioid addiction.

The study conducted examined how early adversities interact with factors such as increased access to opioids to directly influence brain development and function, causing a higher potential for opioid addiction.

The study was lead by UCI researchers and was published in Molecular Psychiatry.

Tallie Z. Baram, MD, PhD, the Danette Shepard Chair in Neurological Sciences at the UCI School of Medicine and one of the senior researchers for the study, was on the take that the widely known factor genetics that plays major role in addiction vulnerability, cannot be solely held responsible for the recent rise in opioid abuse.

To further clarify, the researchers simulated ELA in rats by limiting bedding and nesting materials during a short, postnatal period of time.

In female rats, this led to striking opioid addiction-like characteristics including an increased relapse- behaviour, for example.

As observed in addicted humans, the rats were willing to work very hard (pay a very high price) to obtain the drug.

Baram said: "Ultimately, we found that conditions during sensitive developmental periods can lead to vulnerability to the addictive effects of opioid drugs, especially in females, which is consistent with the prevalence of ELA in heroin-addicted women."

These findings can be used to highlight the importance given to sex differences in future ELA-related studies on opioid addiction, and in future prevention or intervention strategies being developed to address the growing opioid crisis.

The study conducted examined how early adversities interact with factors such as increased access to opioids to directly influence brain development and function, causing a higher potential for opioid addiction.

The study was lead by UCI researchers and was published in Molecular Psychiatry.

The study found that unpredictable, fragmented early life environments may lead to abnormal maturation of certain brain circuits, which profoundly impacts brain function and persists into adolescence and adulthood.

Tallie Z. Baram, MD, PhD, the Danette Shepard Chair in Neurological Sciences at the UCI School of Medicine and one of the senior researchers for the study, was on the take that the widely known factor genetics that plays major role in addiction vulnerability, cannot be solely held responsible for the recent rise in opioid abuse.

To further clarify, the researchers implanted ELA in rats by limiting bedding and nesting materials during a short, postnatal period of time.

In female rats, this led to striking opioid addiction-like characteristics including an increased relapse- behaviour, for example.

As observed in addicted humans, the rats were willing to work very hard (pay a very high price) to obtain the drug.

Baram said: "Ultimately, we found that conditions during sensitive developmental periods can lead to vulnerability to the addictive effects of opioid drugs, especially in females, which is consistent with the prevalence of ELA in heroin-addicted women."

These findings can be used to highlight the importance given to sex differences in future ELA-related studies on opioid addiction, and in future prevention or intervention strategies being developed to address the growing opioid crisis.

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Agencies
May 26,2020

Tedros Adhanom Ghebreyesus, the World Health Organisation's (WHO) Director-General, said that a clinical trial of hydroxychloroquine (HCQ) on COVID-19 patients has come to "a temporary pause", while the safety data of the the anti-malaria drug was being reviewed.

According to the WHO chief, The Lancet medical journal on May 22 had published an observational study on HCQ and chloroquine and its effects on COVID-19 patients that have been hospitalized, reports Xinhua news agency.

The authors of the study reported that among patients receiving the drug, when used alone or with a macrolide, they estimated a higher mortality rate.

"The Executive Group of the Solidarity Trial, representing 10 of the participating countries, met on Saturday (May 23) and has agreed to review a comprehensive analysis and critical appraisal of all evidence available globally," Tedros said in a virtual press conference on Monday.

The review will consider data collected so far in the Solidarity Trial and in particular robust randomized available data, to adequately evaluate the potential benefits and harms from this drug, he said.

"The Executive Group has implemented a temporary pause of the HCQ arm within the Solidarity Trial while the safety data is reviewed by the Data Safety Monitoring Board. The other arms of the trial are continuing," Tedros added.

WHO initiated the Solidarity Trial, a plan to evaluate the safety and efficacy of four drugs and drug combinations against COVID-19 more than two months ago, which include HCQ.

According to the WHO, over 400 hospitals in 35 countries are actively recruiting patients and nearly 3,500 patients have been enrolled from 17 countries under the Solidarity Trial.

Tedros added that the safety concern over the drug related only to the use of HCQ and chloroquine in COVID-19, and "these drugs are accepted as generally safe for use in patients with autoimmune diseases or malaria".

"WHO will provide further updates as we know more," he added.

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