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Bengaluru, June 23: A frustrated chartered accountant has committed suicide after killing his wife and mother-in-law in two different cities of India.

The murder-murder-suicide came amid acrimonious divorce proceedings that might have also involved a property dispute, police said.

Amit flew to Bengaluru last weekend to kill his estranged wife at her Whitefield residence before returning to Kolkata, where he shot dead his mother-in-law and then killed himself at an upscale residential complex in North Kolkata on Monday evening.

Amit and his wife Shilpi Agarwal, who is also a CA, had been living separately since last the two years after their marriage turned sour.

Amit took his 10-year-old son from Bengaluru with him on Monday and dropped him at his uncle’s house before heading to his in-laws’ place Phoolbagan, police said.

Neighbours told cops they heard arguments “appeared to be” over some property documents that Amit wanted his in-laws — 70-year-old Subhas and 62-year-old Lalita Dhandhania — to sign.

The first gunshot was heard a little before 6.30pm, following which Subhas ran out of his flat, bolted the door from outside and took refuge inside his next-door neighbour’s apartment. Police arrived a few minutes later to find Amit and his mother-in-law dead. Police found a suicide note from the flat.

Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.

However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.

New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.

The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.

It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.

"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.

As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.

"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.

"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.

To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.

At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.

Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.

In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.

They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.

Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.

The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.

Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.

Mangaluru, Jan 23: The Muslim Central Committee of Dakshina Kannada and Udupi and Humanity Forum of Mangaluru today handed over a cheque of Rs 10 lakh to the aggrieved family of Naushin, who was killed in arbitrary police firing on December 19 in the city.

A team of philanthropists led by Muslim Central Committee chairman K S Mohammad Masood visited Shaheed Nausheen’s house at Kudroli and handed over the cheque. Several philanthropists have contributed to this humanitarian aid.

Corporator Shamsuddin Kudroli, S M Rasheed Haji, Mansoor Ahmed Azad, Ibrahim Kodichal, Haneef Haji, Asif Deals and Ashraf Kinara were present among others.