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May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.

According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.

"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.

They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.

Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.

"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.

"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.

In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.

"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.

The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.

These children were then confirmed to have COVID-19.

While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.

Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.

According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.

"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.

Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.

While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.

However, he cautioned that more research is needed to confirm their findings.

"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.

Bengaluru, Jun 14: Karnataka Medical Education Minister K Sudhakar on Sunday said there was no question of reimposition of the lockdown amid speculation that it would be done.

"The question of lockdown is not in front of us. There is such speculation as the Prime Minister is holding a video conference with all Chief Ministers on June 16 and 17.

On June 17 our state will be taking part in it at around 3 pm," Mr Sudhakar said in response to a question.

Speaking to reporters at Kalaburagi, he said the current situation would be discussed in that meeting. Mr Sudhakar said the Prime Minister has repeatedly been holding such video conferencing exercises to take stock of the situation and plan for the future.

"There will not be a lockdown anymore according to me," he added.

There has been speculation that there would be another shutdown from this month owing to a rapid rise in the number of cases.

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Mr Sudhakar had on Friday said experts have indicated a surge in COVID-19 cases in the state in August and that the government was taking all precautionary measures in that direction.

As of June 13 evening, cumulatively 6,824 COVID-19 positive cases have been confirmed in the state, which includes 81 deaths and 3,648 discharges.

St. Agnes College (Autonomous), Mangaluru, which is celebrating its centenary year, celebrated 99th college day and merit programme of the academic year 2019-20 in P.U College Auditorium on February 11.

Ms. Philomina Lobo, Retired Director, Secondary Education department of public instructions, Government of India was the chief guest of the programme. The programme began by evoking the blessings of God. Sr Dr M Jeswina A.C, Principal, St Agnes College, Sr Dr M Maria Roopa A.C, the Joint Secretary, Mr. Ronald Pereira PTA Vice President, Mr Charles Pais the Controller of Examinations ,Dr Subha Rao were  present.

Ms. Seemanthini, Assistant Professor, Department of Computer Applications presented the annual college report digitally, highlighting the achievements of the institution, staff and students for the academic year.

Addressing the students, Ms Philomina Lobo advised, “You have knowledge and intelligence but you need to pray for wisdom. Use your talents in the right way.” She also mentioned that the companies today are looking forward for skilful youngsters and asked the students to “be skilful” in order to achieve success in life.

Students received Principal's role of honour, various scholarships and merit certificates for their excellence in academics. The cabinet members of the current academic year were also awarded on the occasion. The Principal gave a token of gratitude to Ms Philomena Lobo, who is also an alumna of the college. Mrs Meera, HOD, Department of History proposed the vote of thanks.