Dinosaurs shrank to birds in order to survive

May 7, 2014

Dinosaurs_shrankLondon, May 7: Dinosaurs are alive and here! Although most dinosaurs went extinct 65 million years ago, one dinosaur lineage survived and lives on today as a major evolutionary success story - the birds, according to a new Oxford study.

The study that'weighed' hundreds of dinosaurs suggests shrinking their bodies may have helped the group that became birds to continue exploiting new ecological niches throughout their evolution, and become hugely successful today.

An international team, led by scientists at Oxford University and the Royal Ontario Museum, estimated the body mass of 426 dinosaur species based on the thickness of their leg bones.

The team found that dinosaurs showed rapid rates of body size evolution shortly after their origins, around 220 million years ago.

However, these soon slowed: only the evolutionary line leading to birds continued to change size at this rate, and continued to do so for 170 million years, producing new ecological diversity not seen in other dinosaurs.

"Dinosaurs aren't extinct; there are about 10,000 species alive today in the form of birds. We wanted to understand the evolutionary links between this exceptional living group, and their Mesozoic relatives, including well-known extinct species like T rex, Triceratops, and Stegosaurus," said Dr Roger Benson of Oxford's Department of Earth Sciences.

"We found exceptional body mass variation in the dinosaur line leading to birds, especially in the feathered dinosaurs called maniraptorans. These include Jurassic Park's Velociraptor, birds, and a huge range of other forms, weighing anything from 15 grams to 3 tonnes, and eating meat, plants, and more omnivorous diets," said Benson, who led the study.

The team believes that small body size might have been key to maintaining evolutionary potential in birds, which broke the lower body size limit of around 1 kilogramme seen in other dinosaurs.

They examined rates of body size evolution on the entire family tree of dinosaurs, sampled throughout their first 160 million years on Earth.

"What we found was striking. Dinosaur body size evolved very rapidly in early forms, likely associated with the invasion of new ecological niches. In general, rates slowed down as these lineages continued to diversify," said Dr David Evans at the Royal Ontario Museum, who co-devised the project.

"But it's the sustained high rates of evolution in the feathered maniraptoran dinosaur lineage that led to birds - second great evolutionary radiation of dinosaurs," said Evans.

The evolutionary line leading to birds kept experimenting with different, often radically smaller, body sizes - enabling new body 'designs' and adaptations to arise more rapidly than among larger dinosaurs.

Other dinosaur groups failed to do this, got locked in to narrow ecological niches, and ultimately went extinct.

The research was published in the journal PLOS Biology.

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News Network
May 7,2020

Toronto, May 7: Scientists have uncovered how bats can carry the MERS coronavirus without getting sick, shedding light on what triggers coronaviruses, including the one behind the COVID-19 pandemic, to jump to humans.

According to the study, published in the journal Scientific Reports, coronaviruses like the Middle East respiratory syndrome (MERS) virus, and the COVID19-causing SARS-CoV-2 virus, are thought to have originated in bats.

While these viruses can cause serious, and often fatal disease in people, bats seem unharmed, the researchers, including those from the University of Saskatchewan (USask) in Canada, said.

"The bats don't get rid of the virus and yet don't get sick. We wanted to understand why the MERS virus doesn't shut down the bat immune responses as it does in humans," said USask microbiologist Vikram Misra.

In the study, the scientists demonstrated that cells from an insect-eating brown bat can be persistently infected with MERS coronavirus for months, due to important adaptations from both the bat and the virus working together.

"Instead of killing bat cells as the virus does with human cells, the MERS coronavirus enters a long-term relationship with the host, maintained by the bat's unique 'super' immune system," said Misra, one of the study's co-authors.

"SARS-CoV-2 is thought to operate in the same way," he added.

Stresses on bats, such as wet markets, other diseases, and habitat loss, may have a role in coronavirus spilling over to other species, the study noted.

"When a bat experiences stress to their immune system, it disrupts this immune system-virus balance and allows the virus to multiply," Misra said.

The scientists, involved in the study, had earlier developed a potential treatment for MERS-CoV, and are currently working towards a vaccine against COVID-19.

While camels are the known intermediate hosts of MERS-CoV, they said bats are suspected to be the ancestral host.

There is no vaccine for either SARS-CoV-2 or MERS, the researchers noted.

Follow latest updates on the COVID-19 pandemic here

"We see that the MERS coronavirus can very quickly adapt itself to a particular niche, and although we do not completely understand what is going on, this demonstrates how coronaviruses are able to jump from species to species so effortlessly," said USask scientist Darryl Falzarano, who co-led the study.

According to Misra, coronaviruses rapidly adapt to the species they infect, but little is known on the molecular interactions of these viruses with their natural bat hosts.

An earlier study had shown that bat coronaviruses can persist in their natural bat host for at least four months of hibernation.

When exposed to the MERS virus, the researchers said, bat cells adapt, not by producing inflammation-causing proteins that are hallmarks of getting sick, but instead by maintaining a natural antiviral response.

On the contrary, they said this function shuts down in other species, including humans.

The MERS virus, the researchers said, also adapts to the bat host cells by very rapidly mutating one specific gene.

These adaptations, according to the study, result in the virus remaining long-term in the bat, but being rendered harmless until something like a disease, or other stressors, upsets this balance.

In future experiments, the scientists hope to understand how the bat-borne MERS virus adapts to infection and replication in human cells.

"This information may be critical for predicting the next bat virus that will cause a pandemic," Misra said.

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Agencies
April 4,2020

Kozhikode, Apr 4: In a bid to maintain the lockdown amid COVID-19 outbreak, Police in Kozhikode is monitoring the situation using drone cameras and making sure that people are not breaking the law.

The police have so far arrested 41 persons who were out on a morning walk on Saturday during the lockdown in the backdrop of coronavirus outbreak.

The SHO of Town South Police Station informed that the accused were later released on bail.
At least 295 cases have been reported in the state so far.

Talking about COVID-19 testing, State Health Minister KK Shailaja told media: "Nine labs are conducting polymerase chain reaction (PCR) tests in Kerala. We've received 2000 rapid test kits and will start rapid tests from tomorrow. If a person tests positive in rapid test, we need to confirm it with PCR test."

The total number of COVID-19 positive cases in India climbed to 3072 on Saturday, according to Ministry of Health and Family Welfare.

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Agencies
March 7,2020

New Delhi, Mar 7: The Union government has issued a Global Invite for Expression of Interest for disinvestment in Bharat Petroleum Corporation Limited (BPCL) from prospective bidders with a minimum net worth of $10 billion as of Saturday.

The EoI submissions can be made till May 2, whereas investor queries will be entertained till April 4.

Another condition pertains to a maximum of four members are permitted in a consortium, and the lead member must hold 40 per cent in proportion. Other members of the consortium must have a minimum $1 billion net worth.

The EOI allows changes in the consortium within 45 days, though the lead member cannot be changed.

The GoI proposes to disinvest its entire shareholding in BPCL comprising 1,14,91,83,592 equity shares held through the Ministry of Petroleum and Natural Gas, which constitutes 52.98 per cent of BPCL's equity share capital, along with the transfer of management control to the strategic buyer (except BPCL's equity shareholding of 61.65 per cent in Numaligarh Refinery Limited (NRL) and management control thereon).

The shareholding of BPCL in NRL will be transferred to a Central Public Sector Enterprise operating in the oil and gas sector under the Ministry and accordingly is not a part of the proposed transaction.

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