'Drunk' Delhi Woman Rams SUV Into Another Car; daughter Goes Blind in an Eye, Mother Killed

Jun 12: The global number of COVID-19 cases has increased to over 7.5 million, while the death toll was nearing 421,000, according to the Johns Hopkins University.

As of Friday morning, the overall number of cases stood at 7,500,777, while the deaths increased to 420,993, the University's Center for Systems Science and Engineering (CSSE) revealed in its latest update.

The US continues with the world's highest number of confirmed cases and deaths at 2,022,488 and 113,803, respectively, according to the CSSE.

In terms of cases, Brazil comes in the second place with 802,828 infections.

This was followed by Russia (501,800), the UK (292,860), India (286,605), Spain (242,707), Italy (236,142), Peru (214,788), France (192,493), Germany (186,691), Iran (180,156), Turkey (174,023), Chile (154,092), Mexico (133,974), Pakistan (125,933) and Saudi Arabia (116,021), the CSSE figures showed.

Regarding fatalities, the UK continues in the second position after the US with 41,364 COVID-19 deaths, which also accounts for the highest number of fatalities in Europe.

The other countries with over 10,000 deaths are Brazil (40,919), Italy (34,167), France (29,349), Spain (27,136) and Mexico (15,944).

Beijing/Zurich, Mar 4: China has approved the use of Swiss drugmaker Roche's anti-inflammation drug Actemra for patients who develop severe complications from the coronavirus as it urgently hunts for new ways to combat the deadly infection that is spreading worldwide.

China is hoping that some older drugs could stop severe cytokine release syndrome (CRS), or cytokine storms, an overreaction of the immune system which is considered a major factor behind catastrophic organ failure and death in some coronavirus patients.

Actemra, a biologic drug approved in 2010 in the United States for rheumatoid arthritis (RA), inhibits high Interleukin 6 (IL-6) protein levels that drive some inflammatory diseases.

China's National Health Commission said in treatment guidelines published online on Wednesday that Actemra can now be used to treat coronavirus patients with serious lung damage and high IL-6 levels.

Separately, researchers in the country are testing Actemra, known generically as tocilizumab, in a clinical trial expected to include 188 coronavirus patients and running until May 10.

Roche, which donated 14 million yuan ($2.02 million) worth of Actemra during February, said the trial was initiated independently by a third party with the aim of exploring the efficacy and safety of the drug in coronavirus patients with CRS.

It added that there was currently no published clinical trial data on the drug's safety or efficacy against the virus.

More than 3,000 people have died and 93,000 have been infected by the novel coronavirus thought to have originated in Wuhan, China, before spreading to around 90 countries including the United States, Italy, Switzerland, France and Germany.

The Swiss company, for which China is its No. 2 market behind the United States, also makes diagnostic gear to detect the coronavirus.

Since Actemra's approval a decade ago, it has become a go-to drug against other inflammatory conditions, including cytokine storms in cancer patients receiving cell therapies from Novartis and Gilead Sciences.

In 2012 it helped save the life of a young U.S. girl, the first child to be treated for leukaemia with Novatis' Kymriah, from a post-treatment rush of IL-6.

Priced at between $20-30,000 annually for RA according to SSR Health, Roche's medicine is also used for rare juvenile arthritis and giant cell arteritis, or inflammation of the blood vessels.

Thiruvananthapuram, Jun 5: One man has been arrested in connection with the death of a pregnant elephant in Palakkad district here, Kerala Forest Minister K Raju said on Friday.

"One accused identified as Wilson has been arrested in connection with the case. More people are involved. The process to arrest all the accused is underway. Strict action will be taken in the matter to ensure such incidents are not repeated in the future," Raju told reporters here.

The elephant had died in Palakkad district on May 27 after it ate a pineapple stuffed with crackers and forest officials said that it died standing in river Velliyar after it suffered an injury in its lower jaw.

Raju said that the forest department has appointed three teams to probe the matter, and added that police are also investigating the incident as explosives were used.

"There may be some type of crackers inside the fruit. In such cases, blast occurs and the animal can not even drink water. The primary post mortem reports said that this case is like that. Let it be investigated," he said.

"Man and animal conflict is natural in our state as people residing close to the forests. The government gives compensation for farmers, Rs 10 lakhs compensation if a person dies in an animal attack," the Minister added.

The death of the pregnant elephant has sparked a controversy, with Kerala Chief Minister Pinarayi Vijayan terming the unfortunate death as "a painful thing" and Union Environment Minister Prakash Javadekar saying that the Centre has taken a "serious note" of the incident.

According to the preliminary post-mortem report, the immediate cause of the death of the female elephant was drowning followed by inhalation of water leading to lung failure.

The elephant was seen standing in the river with its mouth and trunk in the water for some relief from the pain after the explosive-filled fruit exploded in its mouth.