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Mumbai, Apr 29: Irrfan Khan, one of India's finest and most versatile actors, lost his battle with a rare form of cancer and died in a Mumbai hospital on Wednesday, a statement from his family said. He was 54

Irrfan, who was diagnosed with neuroendocrine tumour in 2018, is survived by his wife Sutapa and his sons Babil and Ayaan.

It is the second tragedy for the family in less than a week. The ?Maqbool? actor lost his mother, 95-year-old Saeeda Begum, in Jaipur just four days ago and could not attend the funeral because of the nationwide lockdown.

Irrfan, that rare actor who straddled multiple worlds, making his mark in both international and Indian cinema in roles intense and light-hearted, was admitted to the intensive care unit of the Kokilaben Dhirubhai Ambani Hospital with a colon infection

?It's saddening that this day, we have to bring forward the news of him passing away. Irrfan was a strong soul, someone who fought till the very end and always inspired everyone who came close to him. After having been struck by lightning in 2018 with the news of a rare cancer, he took life soon after as it came and he fought the many battles that came with it,? the statement from his family said

?Surrounded by his love, his family for whom he most cared about, he left for heavenly abode, leaving behind truly a legacy of his own. We all pray and hope that he is at peace. And to resonate and part with his words he had said, 'As if I was tasting life for the first time, the magical side of it',? it added.

The news of his death was first confirmed by his "Piku" director Shoojit Sircar who sent his condolences to the family and doffed his hat to the actor's fighting spirit

"My dear friend Irfaan. You fought and fought and fought. I will always be proud of you.. we shall meet again.. condolences to Sutapa and Babil.. you too fought, Sutapa you gave everything possible in this fight. Peace and Om shanti. Irfaan Khan salute," the director said on Twitter.

Irrfan's death came the morning after news that he had been admitted to the ICU with a colon infection.

The self-effacing National Award winner, who acted in films as diverse as ?Life of Pi?, ?The Namesake? and ?Haasil?, had stayed away from the public eye after his diagnosis in 2018 when he went to the UK for treatment.

He returned home in 2019 and shot for "Angrezi Medium", the sequel to his 2017 hit "Hindi Medium". However, his health condition prevented him from promoting the movie, which hit the theatres in March just before the lockdown that began on March 25.

Hollywood star Joaquin Phoenix finally ended his dry run at the Oscars as he picked up the best actor trophy for his performance in and as "Joker" at the 92nd Academy Awards.

The 45-year-old actor had earlier bagged a BAFTA, a Golden Globe and a Screen Actors Guild Award for his turn as a failed, unhinged stand-up comedian who descends into chaos.

In a lengthy and rambling speech, Phoenix touched upon racism, climate change and gender inequality. He also remembered his brother River Phoenix, who died of a drug overdose at the age of 23 in 1993.

"When he was 17, my brother wrote this lyric. He said, 'run to the rescue with love and peace will follow'," Phoenix said. At the Academy Awards and the entire Hollywood award season, Phoenix had emerged as an undisputed frontrunner even though he was up against the likes of Leonardo DiCaprio ("Once Upon a Time in Hollywood"), Adam Driver ("Marriage Story"), "Antonio Banderas ("Pain & Glory") and Jonathan Pryce ("The Two Popes").

An Oscar had eluded Phoenix for the most part of his career, despite his successful collaborations with Ridley Scott ("Gladiator"), James Mangold ("Walk The Line") and Paul Thomas Anderson ("The Master"), all of which had earned him nominations.

But as Arthur Fleck aka The Joker, Phoenix finally managed to break that jinx and became the second actor to win an Oscar for playing the DC comic book villain after the posthumous best supporting actor win to Heath Ledger in 2008.

As Joker, Phoenix took a deep dive into character, capturing its essence as well as maniacal spirit in both body and soul.

He lost 52 pounds to get into the physicality of Fleck and turned to a pathological disorder to get his distinct laughter right.

Phillips wrote the part keeping Phoenix in mind though the actor took some convincing to play the role.

Phoenix started the film's festival circuit tour on a positive note at Cannes last year that followed by stops at Venice and Toronto.

The film had also courted controversies, owing to its theme of gun violence in the movie as well as Phoenix's temperamental press tour that saw him walking out of an interview midway.

But critics and the fans loved the actor's riveting turn in the movie and his pointed speeches.

At the Golden Globes, he called out the industry for its insensitivity towards climate change and pulled up his peers for using private jets for travel, while at the SAGs, he joked how he would always lose a role to DiCaprio and asked Christian Bale to deliver a bad performance for once in his career.

In his acceptance speech at the BAFTAs, Phoenix acknowledged the lack of diversity in the nominations, calling himself a part of the problem. Phoenix's career most praised performances include "Signs ", "We Own the Night", "Two Lovers", "The Immigrant", "Her", "You Were Never Really Here" and "Inherent Vice".