Herbal remedies may help kids with gastrointestinal issues

May 6, 2017

May 6: Many parents of children with debilitating gastrointestinal disorders may be frustrated by the lack of good treatment options and tempted to try herbal remedies at home, but a new study suggests they should proceed with caution.

medicineResearchers examined data from 14 previously published studies with a total of 1,927 children suffering from problems like diarrhea, dehydration, colic, constipation, abdominal pain and irritable bowel syndrome. They didn’t have enough data to combine results from multiple small studies to offer definitive proof that herbal remedies might work for any of these health problems.

But some of the small studies did suggest certain herbal medicines might help ease diarrhea, abdominal pain and colic. And the studies didn’t find serious side effects associated with herbal remedies.“The lack of conclusive research is unfortunately a general problem in pediatrics, but a special problem in herbal medicine is that for many herbal remedies no licensed and standardized products are available,” said lead study author Dr. Dennis Anheyer of the University of Duisburg-Essen in Germany.

In other words, even if evidence shows an herb may be safe and effective for a specific health problem, that doesn’t necessarily mean that every single version of that herb available for sale would work as well or be free of side effects.

When researchers looked at four studies with a total of 424 participants, they found some evidence suggesting that a variety of herbal remedies might help diarrhea: a plant in the rose family called potentilla erecta, carob bean juice, and an herbal compound preparation with chamomile.

One study with 120 participants also suggests that peppermint oil might help curb the duration, frequency and severity chronic abdominal pain that doesn’t have a clear medical explanation.And, fennel might help ease colic symptoms in babies according to a review of five small studies of herbal remedies for infant colic.

While it’s possible herbal remedies might be used in addition to traditional medications or to help reduce reliance on drug therapy, parents should still see a doctor before trying out herbal therapies on their own, Anheyer said by email.

Another reason for caution is that even the studies in the current analysis that found herbal remedies effective don’t show how large the effects are, noted Dr. Peter Lucassen, a researcher at Radboud University Medical Center in the Netherlands who wasn’t involved in the study.

These small studies might get results that find herbs are statistically better than no treatment or alternative therapies, but the difference still might not be big enough to have a meaningful clinical impact on patients’ symptoms, Lucassen said by email.“I would not advocate any of the herbal medicine because the article does not provide any data about how large the effects are,” Lucassen said.

Often, herbal remedies combine a variety of ingredients and use differing amounts of the main ingredients, which may alter how well they work and how safe they are for kids, Lucassen added. They might also contain chemicals not found in prescription medications that have dangerous side effects or a risk of overdose.

And there’s another reason parents shouldn’t try herbal remedies without seeing a doctor.“Delayed diagnosis might be the result of herbal medications because parents seek help too late because they try the herbs first,” Lucassen said.

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Agencies
July 8,2020

Probiotics that broaden the mix of helpful bacteria in the gut may help to ease depression, say researchers.

Foods that broaden the profile of helpful bacteria in the gut are collectively known as probiotics. These "good bacteria" can be taken as supplements, or found naturally in yoghurts or fermented foods.

For the findings, the research team from the University of Brighton in the UK searched for relevant studies published in English between 2003 and 2019, which looked at the potential therapeutic contribution of pre-and probiotics in adults with depression and/or anxiety disorders.

Out of an initial haul of 71 studies, just seven met all the criteria for inclusion. All 7 investigated at least one probiotic strain; four looked at the effect of combinations of multiple strains.In all, 12 probiotic strains featured in the selected studies, primarily Lactobacillus acidophilus, Lactobacillus casei, and Bifidobacterium bifidium.

One study looked at combined pre-probiotic treatment, while one looked at prebiotic therapy by itself. The studies varied considerably in their design, methods used, and clinical considerations, but all of them concluded that probiotic supplements either alone or in combination with prebiotics may be linked to measurable reductions in depression.

And every study showed a significant fall or improvement in anxiety symptoms and clinically relevant changes in biochemical measures of anxiety or depression with probiotic or combined pre-probiotic use.

Of the 12 different probiotics investigated, 11 were potentially useful, the findings showed.'Probiotics may help reduce the production of inflammatory chemicals, such as cytokines, as is the case in inflammatory bowel disease, the researchers suggested.

"They may help direct the action of tryptophan, a chemical thought to be important in the gut-brain axis in psychiatric disorders," they added.

In this way, with a better understanding of the mechanisms, probiotics may prove to be a useful tool across a wide range of conditions," the authors wrote.

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Agencies
March 16,2020

New Delhi, Mar 16: A recent survey across 140 districts of the country shows that about 54 per cent of Indians are finding travelling to be unsafe as the deadly coronavirus (COVID-19) pandemic sweeps globally.

The big worry that people have is community transmission, something that researchers from around the world have approximated at 10 per cent of total infections and more common in places like Wuhan in China, South Korea, Iran and Italy.

The months of March to June have historically been high travel season for most Indians, largely due to the summer vacations in schools. "But it seems that Indians do not want to take a chance with this rather scary virus and are either cancelling or postponing their travel plans," concluded the survey by LocalCircles.

The survey gathered more than 22,000 responses from participants in tier one, two and three cities. It said 48 per cent Indians plan to cancel their international business travel for the next four months.

Besides, nearly 38 per cent of respondents said they had to pay cancellation fee to the website, travel agent, airline or railways.

"These are testing times for the entire travel and tourism industry -- airlines, hotels, travel agents as well as small tour and taxi operators. The best solution at this point is to adjust cost structures, stay flexible and work with a collective approach to minimise the period of impact to both citizens and business," said LocalCircles.

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Agencies
July 4,2020

The Union health ministry on Friday revised the dosage of anti-viral drug remdesivir to be administered to coronavirus patients in the moderate stage of illness from the earlier six days to five days as it issued an updated 'Clinical Management Protocols for COVID-19'.

The drug, administered in the form of injection, should be given at a dose of 200 mg on day one followed by 100 mg daily for four days (total five days), the new treatment protocols stated.

The Health Ministry on June 13 had allowed the use of remdesivir for restricted emergency use in moderate cases under "investigational therapies".

"Under emergency use authorisation, remdesivir may be considered for patients in moderate stage requiring oxygen support," the document stated.

It is not recommended for those with severe renal impairment and high level of liver enzymes, pregnant and lactating women, and those below 12 years, it said.

The ministry also okayed off-label application of tocilizumab, a drug that modifies the immune system or its functioning, and convalescent plasma for treating COVID-19 patients in the moderate stage of illness as "investigational therapies".

It also recommended hydroxychloroquine for patients during the early course of the disease and not for critically-ill patients.

On June 27, the ministry had included an inexpensive, widely used steroid dexamethasone in treatment protocols for COVID-19 patients in the moderate to severe stages of their illness among other therapeutic measures.

The ministry advised use of dexamethasone, which is already used in a wide range of conditions for its anti-inflammatory and immunosuppressant effects, as an alternative choice to methylprednisolone for managing moderate to severe cases of coronavirus infection.

India's COVID-19 cases soared by over 20,000 in a day for the first time taking the country's total tally to 6,25,544 on Friday while the death toll climbed to 18,213 with 379 new fatalities, according to the Union Health Ministry data updated at 8 am.

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