Injecting cytokines to reactivate immune system could be useful in treating COVID19 patients, says Bengaluru doctor

News Network
March 27, 2020

Bengaluru, Mar 27: Oncologist Dr. Vishal Rao, HCG Hospital Bengaluru on Friday said that human body cells release interferon chemical to kill viruses but it cannot be released by cells in the case of COVID-19 cases, leading to weak immune system. However, a therapy of specific concoction could be useful in treating COVID-19 patients.

"We got hold of some preprint suggesting that interferon is effective in COVID19," said Rao.

Speaking to news agency, he continued saying "When we withdraw blood for regular check-ups, we get buffy coat which can be used to take out cells and form interferon. These two chemicals and some other cytokines, in a specific concoction, could be potentially very useful in treating COVID-19 patients."

Rao said that they have built a concoction of cytokines which can be injected to reactivate immune system in COVID-19 patients.

"We are in a very initial stage and hope to be ready with its first set by this weekend. We have applied to the governement for an expedited review. We have also presented this before the state government" said Rao.

"We have a team of infection specialist, ICU team and other...all of us have worked together to build something that we believe. We want to serve the society at this hour of need," he added.

Dr Rao clarified that this is not a vaccine and this particular interferon therapy does not help to prevent the infection of COVID-19. However, this is focused and targeted towards COVID-19 positive patients or those who have just incubated the virus.

"We believe that in early stages as well as the patients who have just incubated, this particular therapy of interferon gama and other concoction of cytokines could be an effective method. In the late stages we are looking at specific dosage of the cells which are our own body cells which can actually be affective and could also be of use for the ventilator patients," he added.

Meanwhile, Dr Gururaj, Immunologist and Scientist told ANI that they are trying to cover two aspects, one is the early stage patients where they are trying to improve their immune systems.

"As Dr Vishal said, we are trying to see whether we can use the cytokines from our own immune cells which is a natural process but it is hampered in infected patients," said Dr Gururaj.

"In the last phase we are using cells which are used from the bone marrow of the patient or donors. We can use those cells to reduce the inflation and so called cytokines release syndrome which is basically the inflammatory response of the body," he added.

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News Network
March 24,2020

Bhatkal, Mar 24: Two people, who arrived from Dubai at Mangaluru International Airport on March 21, were tested positive for coronavirus.

A 40-year-old man has been tested positive for the dreaded killer disease Covid-19 while 65-year-old man, who arrived on same day from Dubai, has also been tested positive for the virus. The person reportedly took train from Mangaluru to Bhatkal after arriving at Mangaluru International Airport.

Both of them hailed from Bhatkal and are currently hospitalised and their direct contacts are being traced by the authorities.

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News Network
August 3,2020

Bengaluru, Aug 3: All those who met Karnataka Chief Minister B S Yediyurappa, who has tested positive for Covid-19, in the last three-four days will have to be quarantined, Medical Education Minister Sudhakar K said on Monday.

He also said those who came in contact with Yediyurappa in a couple of programmes in the past week are being traced.

Sudhakar, a medical doctor himself, said Yediyurappa has "very mild cough and his chest is clear."

"I think eight to ten days," he told news agency when asked how long the Chief Minister would have to remain in hospital.

Sudhakar said he is also getting himself tested as a few of his office staff had tested positive.

"All those who met the Chief Minister in the last 3-4 days...ideally they should be quarantined till they receive their results/report. Those who came in contact with him in a couple of programmes will have to isolate themselves and subject themselves for testing," the Minister said.

On the Chief Minister meeting Governor Vajubhai Vala, along with Home Minister Basavaraj Bommai last Friday, Sudhakar said as a result "They also become primary contacts. Ideally, they should also be quarantined and tested."

Yediyurappa who was hospitalised on Sunday night after testing positive for Covid-19 was "doing well" and is "clinically stable", the hospital treating him said.

The 77-year old leader is being monitored by a team of doctors at the Manipal hospital here.

"He is doing well, is clinically stable and will be monitored closely by our team," the hospital said in a statement late last night.

"I have tested positive for coronavirus. Whilst I am fine, I am being hospitalised as a precaution on the recommendation of doctors. I request those who have come in contact with me recently to be observant and exercise self-quarantine," Yediyurappa had said in his tweet.

Yediyurappa was in home quarantine a couple of weeks ago, after some staff members in his home office were found infected with the virus. Subsequently, he tested negative for Covid-19.

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News Network
April 29,2020

Bengaluru, Apr 29: As many as 11 more people have tested positive for the coronavirus in the last 24 hours in Karnataka, said the State's Health Department on Wednesday.

According to an official statement, 11 new COVID-19 positive cases were reported from 5 pm on April 28 to 5 pm on April 29.

"With this, the total number of positive coronavirus cases in the state has mounted to 534, of which 20 deaths have been reported and 215 people have recovered," added the statement.

Of 20 coronavirus patients who died, one death was due to the non-COVID cause, the statement further said.

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