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Thiruvanathapuram, Mar 27: The state is heading for its worst ever crisis with coronavirus cases increasing rapidly and Kasargod district the worst hit. On Friday alone 39 positive cases were reported in the state of which 34 are from Kasargod.

Chief minister Pinarayi Vijayan said the situation is grave and Kasargod has been the worst hit. More than the positive cases reported in the district, the worrying factor is that many people have come into contact with these positive cases.

The chief minister warned that the government will be forced to declare the names of the people who are defying the quarantine guidelines in the district. More people have been put under risk in the district and the district administration is much concerned since the results of 215 samples are yet to come.

There is no other way but to tighten the restrictions imposed in the district against the people coming out of their houses. The government has decided to provide more facilities to the hospitals in Kasargod and Kannur to meet an emergency.

The medical college hospital in Kannur will be converted into a coronavirus hospital with 200 bed strength. Steps have been taken to equip the medical college hospital with more facilities. The Central University at kasargood will be converted into as a temporary coronavirus treatment centre. 

The state has also requested permission from ICMR to begin the testing facility here, said the chief minister.

The total number of positive cases reported in the state have now become 176 of which 12 have been discharged after testing negative. At present 164 positive people are admitted in several hospitals of the state.

On Friday of the 39 positive cases, two are from Kannur and one each from Thrissur, Kollam and Kozhikode. With this all the districts in the state have been now affected with coronavirus.

May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.

According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.

"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.

They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.

Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.

"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.

"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.

In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.

"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.

The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.

These children were then confirmed to have COVID-19.

While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.

Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.

According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.

"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.

Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.

While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.

However, he cautioned that more research is needed to confirm their findings.

"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.

Madikeri, Mar 16: Three suspected cases of COVID-19, who returned from a foreign country recently have been admitted to the isolation ward of the district hospital here, the district administration said on Monday.

The samples of the suspected cases have been sent for lab tests and the reports are being awaited, sources said.

As many as 74 people have been placed under home quarantine in Kodagu (also known as Coorg) as a precautionary measure following their return from abroad, a press note from the Deputy Commissioner Annies Kanmani Joy said.