Mangaluru: Young poetess Mafazah Sharafuddin’s Labyrinths of Emotions released

Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.

However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.

New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.

The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.

It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.

"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.

As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.

"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.

"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.

To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.

At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.

Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.

In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.

They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.

Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.

The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.

Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.

Bareilly, Jun 22: The All India Tanzeem Ulama-e-Islam, a religious and social organisation headed by five senior clerics, has issued a fatwa to boycott Chinese products in the country.

The clerics said the community members should stand with the army and government in this hour.

Expressing concern over India-China face-off, National general secretary of All India Tanzeem Ulama-e-Islam, Maulana Shahbuddin Rizvi expressed concern over the India-China face-off and said, "A fatwa has been passed for boycotting Chinese products on a query posted by a Bareilly-based resident. The clerics in the fatwa have condemned the conspiracy of China to encroach upon Indian land and the killing of our brave soldiers."

The panel of five clerics include national president of All India Tanzeem Ulama-e-Islam Mufti Ashfaq Hussain Qadri, Mufti Iqbal Ahmad Misbahi, Mufti Tauqir Ahmad Qadri, Mufti Hashim Raza Khan and Qari Saghir Ahmad Rizvi.

Bengaluru, Jan 30: A kidnap case in Bengaluru has proved that crime-based series on TV channels can inspire youth to commit crimes. 21-year-old Chirag R Mehta, who kidnapped a schoolboy and got arrested within an hour after demanding Rs 5 lakh ransom, has told police that he thought of abducting the boy after watching Crime Patrol, a popular Hindi crime anthology series created by Subramanian S. lyer for Sony TV. The kidnapped schoolboy was rescued by the police and reunited with his parents. Son of a gift shop owner from Basavanagudi area in Bengaluru, Chirag has reportedly told police that decided to make some quick money to spend on cricket betting and gambling after learning kidnap tricks from the ‘Crime Patrol’. According to police, Chirag reached a private school around 3pm on Tuesday on a Bounce rental bike and zeroed in on a fourth standard student who was walking out of school. He told the boy he was his father's friend and that he required help to search for a relative who had gone missing. The boy believed Chirag and rode pillion on the bike. Chirag then engaged the boy in conversation and learnt about his father's business and got his mobile phone number. He then made a call to the boy's father, demanded Rs 5 lakh and warned him against approaching cops. However, the boy's father alerted Cottonpet police and special teams were formed to crack the case. While Cottonpet inspector Venkatesh TC's squad verified CCTV footage in and around the school, Chamarajpet inspector BG Kumaraswamy's team started tracking the suspect's mobile phone movements. An hour later, the suspect's location was traced to a hotel on the Lavelle Road-St Mark's Road stretch. Police rushed there, rescued the boy and arrested Chirag.