SACH A WONDERFUL JOURNEY

[email protected] (G Unnikrishnan, DHNS)
December 24, 2012

Sachin_wonderful

March 27, 1994. That day will always remain seminal in Indian cricket history. It was on that day India found their and world's finest opening batsman in 50-over cricket at Eden Park, Auckland.

Sachin Tendulkar smashed a 48-ball 82 on that day, beginning a long 18-year stint at the pole position after having made his debut five years earlier. Innumerable records have been set during that journey, and some of them will never be broken.

The glitz of those numbers, however, masks two elements that made Tendulkar the most efficient one-day batsman of all time — adaptability and ability to withstand pressure of expectations from a billion fans for whom failure -- of Tendulkar and the team -- was not an option.

From 1994 to 2000 Tendulkar was at his peak of fitness and abilities, and there were no bowlers in the world who didn't face the wrath of his willow; it was classy and eye-catching at the same time.

He scored 8220 runs from 198 matches at 45.66 with 27 hundreds in that seven years, and it was that period that really converted Tendulkar into a household name and a brand worth millions.

Tendulkar had contemporaries like Matthew Hayden, Adam Gilchrist, Sanath Jayasuriya and Saeed Anwar who opened the innings, but none of them controlled a team's fortunes like the Mumbaikar. None of them had to enter the field in the knowledge that a personal failure would more likely end up in team's failure. It might have been immense pressure for one individual to bare. But Tendulkar stayed calm all the while.

There never was an occasion when he shied away from the responsibility or complained about the perils of one-man efforts. Tendulkar had to remain in that high-pressure boiling container not for just one series or a few months, but for years together.

There was no relief point. There was no one to share his burden. He couldn't have been blamed for feeling like the loneliest man on the planet because few could understand his situation. He was India's sole hope. Perhaps, those two 'Desert Storm' innings (143 and 134) against Australia at Sharjah in 1998 was also a reflection of India's desperation and dependence on him.

But in the late 90s and early 2000s emerged a set of cricketers who finally set Tendulkar free from that lonley place. Sourav Ganguly evolved into a fine opener in his own right, giving long company to Tendulkar, Rahul Dravid overcame his limitations as a limited-over batsman to score more than 10000 runs, once Ganguly was done with his career Virender Sehwag, a malevolent force at top, came to partner Tendulkar, and then others like Yuvraj Singh and Mahendra Singh Dhoni emerged at different times as India finally became a one-day super power.

Along with it, Tendulkar's role has also changed. He was no longer the lone match-winner, he became one of the match-winners among a host of that breed. It needed a change of mindset as well by Tendulkar to accept that shared significance in the team set up, and he adapted quite beautifully.

As a batsman, he was no longer required to carry India alone and a couple of injuries, most noticeably a tennis elbow, made it mandatory for Tendulkar to revisit his approach to batting. Some great players like Viv Richards never changed their methods, but here Tendulkar eschewed the ego factor and transformed into a different batsman post 2000.

Those twinkling forays down the pitch, a common feature of a Tendulkar innings in the 90s, particularly against spinners, were curtailed and shots over the top of the infield too became a rarity, and percentage cricket took over. The Tendulkar Mark 2 wasn't adrenaline-rising, but he was clinical cold and only more effective. There wasn't a batsman who was more aware than Tendulkar of the gaps on the field and angles.

Still, the impish kid in him would awake at times, largely in the shape of that upper cuts and paddle sweeps, shots he developed into a major part of his arsenal in the later part of his career.

In the new millenium, he amassed 8527 runs from 200 one-dayers at 48.17 with 22 hundreds, reflecting his steady impact and relevance even while the one-dayers underwent structural changes in the last decade.

The 85 against Pakistan at Mohali in the 2011 World Cup semifinals underscored that. Saeed Ajmal tormented him with doosras, and Pakistan fielders dropped him five times on that evening, but he never gave the fight away. For sometime, the clock ticked back to the 90s, and Tendulkar became India's pressure carrier. And like in the 90s, he soaked in the pressure, and India won. It was an ugly scrap, but it was also a shining pointer to the secret of his success.




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News Network
May 30,2020

May 30: Patients undergoing surgery after contracting the novel coronavirus are at an increased risk of postoperative death, according to a new study published in The Lancet journal which may lead to better treatment guidelines for COVID-19.

In the study, the scientists, including those from the University of Birmingham in the UK, examined data from 1,128 patients from 235 hospitals from a total of 24 countries.

Among COVID-19 patients who underwent surgery, they said the death rates approach those of the sickest patients admitted to intensive care after contracting the virus.

The scientists noted that SARS-CoV-2 infected patients who undergo surgery, experience substantially worse postoperative outcomes than would be expected for similar patients who do not have the infection.

According to the study, the 30-day mortality among these patients was nearly 24 per cent.

The researchers noted that mortality was disproportionately high across all subgroups, including those who underwent elective surgery (18.9 per cent), and emergency surgery (25.6 per cent).

Those who underwent minor surgery, such as appendicectomy or hernia repair (16.3 per cent), and major surgery such as hip surgery or for colon cancer also had higher mortality rates (26.9 per cent), the study said.

According to the study, the mortality rates were higher in men versus women, and in patients aged 70 years or over versus those aged under 70 years.

The scientists said in addition to age and sex, risk factors for postoperative death also included having severe pre-existing medical problems, undergoing cancer surgery, undergoing major procedures, and undergoing emergency surgery.

"We would normally expect mortality for patients having minor or elective surgery to be under 1 per cent, but our study suggests that in SARS-CoV-2 patients these mortality rates are much higher in both minor surgery (16.3%) and elective surgery (18.9%)," said study co-author Aneel Bhangu from the University of Birmingham.

Bhangu said these mortality rates are greater than those reported for even the highest-risk patients before the pandemic.

Citing an example from the 2019 UK National Emergency Laparotomy Audit report, he said the 30-day mortality was 16.9 per cent in the highest-risk patients.

Based on an earlier study across 58 countries, Bhangu said the 30-day mortality was 14.9 per cent in patients undergoing high-risk emergency surgery.

"We recommend that thresholds for surgery during the SARS-CoV-2 pandemic should be raised compared to normal practice," he said.

"For example, men aged 70 years and over undergoing emergency surgery are at particularly high risk of mortality, so these patients may benefit from their procedures being postponed," Bhangu added.

The study also noted that patients undergoing surgery are a vulnerable group at risk of SARS-CoV-2 exposure in hospital.

It noted that the patients may also be particularly susceptible to subsequent pulmonary complications, due to inflammatory and immunosuppressive responses to surgery and mechanical ventilation.

The scientists found that overall in the 30 days following surgery 51 per cent of patients developed a pneumonia, acute respiratory distress syndrome, or required unexpected ventilation.

Nearly 82 per cent of the patients who died had experienced pulmonary complications, the researchers said.

"Worldwide an estimated 28.4 million elective operations were cancelled due to disruption caused by COVID-19," said co-author Dmitri Nepogodiev from the University of Birmingham.

"Our data suggests that it was the right decision to postpone operations at a time when patients were at risk of being infected with SARS-CoV-2 in hospital," Nepogodiev said.

According to the researchers, there's now an urgent need for investment by governments and health providers in to measures which ensure that as surgery restarts patient safety is prioritised.

They said this includes the provision of adequate personal protective equipment (PPE), establishment of pathways for rapid preoperative SARS-CoV-2 testing, and consideration of the role of dedicated 'cold' surgical centres.

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News Network
April 17,2020

Paris, Apr 17: Even as virologists zero in on the virus that causes COVID-19, a very basic question remains unanswered: do those who recover from the disease have immunity?

There is no clear answer to this question, experts say, even if many have assumed that contracting the potentially deadly disease confers immunity, at least for a while.

"Being immunised means that you have developed an immune response against a virus such that you can repulse it," explained Eric Vivier, a professor of immunology in the public hospital system in Marseilles.

"Our immune systems remember, which normally prevents you from being infected by the same virus later on."

For some viral diseases such a measles, overcoming the sickness confers immunity for life.

But for RNA-based viruses such as Sars-Cov-2 -- the scientific name for the bug that causes the COVID-19 disease -- it takes about three weeks to build up a sufficient quantity of antibodies, and even then they may provide protection for only a few months, Vivier told AFP.

At least that is the theory. In reality, the new coronavirus has thrown up one surprise after another, to the point where virologists and epidemiologists are sure of very little.

"We do not have the answers to that -- it's an unknown," Michael Ryan, executive director of the World Health Organization's Emergencies Programme said in a press conference this week when asked how long a recovered COVID-19 patient would have immunity.

"We would expect that to be a reasonable period of protection, but it is very difficult to say with a new virus -- we can only extrapolate from other coronaviruses, and even that data is quite limited."

For SARS, which killed about 800 people across the world in 2002 and 2003, recovered patients remained protected "for about three years, on average," Francois Balloux director of the Genetics Institute at University College London, said.

"One can certainly get reinfected, but after how much time? We'll only know retroactively."

A recent study from China that has not gone through peer review reported on rhesus monkeys that recovered from Sars-Cov-2 and did not get reinfected when exposed once again to the virus.

"But that doesn't really reveal anything," said Pasteur Institute researcher Frederic Tangy, noting that the experiment unfolded over only a month.

Indeed,several cases from South Korea -- one of the first countries hit by the new coronavirus -- found that patients who recovered from COVID-19 later tested positive for the virus.

But there are several ways to explain that outcome, scientists cautioned.

While it is not impossible that these individuals became infected a second time, there is little evidence this is what happened.

More likely, said Balloux, is that the virus never completely disappeared in the first place and remains -- dormant and asymptomatic -- as a "chronic infection", like herpes.

As tests for live virus and antibodies have not yet been perfected, it is also possible that these patients at some point tested "false negative" when in fact they had not rid themselves of the pathogen.

"That suggests that people remain infected for a long time -- several weeks," Balloux added. "That is not ideal."

Another pre-publication study that looked at 175 recovered patients in Shanghai showed different concentrations of protective antibodies 10 to 15 days after the onset of symptoms.

"But whether that antibody response actually means immunity is a separate question," commented Maria Van Kerhove, Technical Lead of the WHO Emergencies Programme.

"That's something we really need to better understand -- what does that antibody response look like in terms of immunity."

Indeed, a host of questions remain.

"We are at the stage of asking whether someone who has overcome COVID-19 is really that protected," said Jean-Francois Delfraissy, president of France's official science advisory board.

For Tangy, an even grimmer reality cannot be excluded.

"It is possible that the antibodies that someone develops against the virus could actually increase the risk of the disease becoming worse," he said, noting that the most serious symptoms come later, after the patient had formed antibodies.

For the moment, it is also unclear whose antibodies are more potent in beating back the disease: someone who nearly died, or someone with only light symptoms or even no symptoms at all. And does age make a difference?

Faced with all these uncertainties, some experts have doubts about the wisdom of persuing a "herd immunity" strategy such that the virus -- unable to find new victims -- peters out by itself when a majority of the population is immune.

"The only real solution for now is a vaccine," Archie Clements, a professor at Curtin University in Perth Australia, told AFP.

At the same time, laboratories are developing a slew of antibody tests to see what proportion of the population in different countries and regions have been contaminated.

Such an approach has been favoured in Britain and Finland, while in Germany some experts have floated the idea of an "immunity passport" that would allow people to go back to work.

"It's too premature at this point," said Saad Omer, a professor of infectious diseases at the Yale School of Medicine.

"We should be able to get clearer data very quickly -- in a couple of months -- when there will be reliable antibody tests with sensitivity and specificity."

One concern is "false positives" caused by the tests detecting antibodies unrelated to COVID-19.

The idea of immunity passports or certificates also raises ethical questions, researchers say.

"People who absolutely need to work -- to feed their families, for example -- could try to get infected," Balloux.

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Agencies
June 10,2020

US dictionary Merriam-Webster will update the meaning of the word "racism" after being contacted by a Missouri black woman, who claimed the current definition fell short of including the systematic oppression of people of colour, according to media reports.

"A revision to the entry for racism is now being drafted to be added to the dictionary soon, and we are also planning to revise the entries of other words that are related to racism or have racial connotations," according to a statement of the 189-year-old dictionary shared by Kennedy Mitchum, a recent graduate of Drake University in Iowa, on her Facebook.

Mitchum, 22, emailed the dictionary last month, following the death of African American George Floyd in the custody of four Minneapolis police officers, Xinhua news agency reported.

"I kept having to tell them that definition is not representative of what is actually happening in the world," Mitchum told CNN. "The way that racism occurs in real life is not just prejudice, it's the systemic racism that is happening for a lot of black Americans."

Merriam-Webster's first definition of racism is "a belief that race is the primary determinant of human traits and capacities and that racial differences produce an inherent superiority of a particular race."

"It's not just disliking someone because of their race," Mitchum wrote in a Facebook post on Friday. "This current fight we are in is evidence of that, lives are at stake because of the systems of oppression that go hand-in-hand with racism."

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